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Conducting ChIP-Seq with Low Cell Numbers

An interview with Dr. Kathyrn Cunningham at SfN 2018, providing advice on carrying out Chromatin Immunoprecipitation Sequencing (ChIP-seq) with low cell numbers.

From Active Motif 14 Jan 2019

Study raises hopes for new approaches to treat osteoporosis

A handful of brain cells deep in the brain may play a surprising role in controlling women's bone density, according to new research by UC San Francisco and UCLA scientists.

11 Jan 2019

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

UCLA researchers led by Dr. Donald Kohn have created a method for modifying blood stem cells to reverse the genetic mutation that causes a life-threatening autoimmune syndrome called IPEX.

11 Jan 2019

Drug combination has added benefit for patients with melanoma

The German Institute for Quality and Efficiency in Health Care investigated whether the drug combinations of dabrafenib plus trametinib and of encorafenib plus binimetinib have an added benefit in comparison with the appropriate comparator therapies for patients with melanoma.

9 Jan 2019

Researchers develop new method of analysis to map cellular locations of proteins

Researchers at Karolinska Institutet and SciLifeLab have developed a new method of analysis that maps the location of proteins in the cell. The information has been compiled in a database that is accessible to researchers around the world.

3 Jan 2019

Researchers reveal cause of possible genetic problems in mitochondria

A group of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine has revealed the importance of eliminating any excess of defective products that might have accumulated in the mitochondria, as its presence generates mitochondrial instability and information loss on the mitochondrial genome.

3 Jan 2019

New mechanism may explain neurons shrinking in Huntington's disease

A hallmark of neurodegenerative diseases like Huntington's is the progressive death of nerve cells in the brain. The cells don't die quickly, though. They first start to disconnect from each other because their neurites -- long finger-like extensions that make connections all through the brain -- become smaller.

25 Dec 2018

The role of galanin-like peptide in regulating feeding behavior and energy metabolism

Galanin-like peptide is a short peptide made up of 60 amino acid residues. This sequence is homologous across several species. The hypothalamic arcuate nucleus is the place where GALP is produced. GALP has diverse physiological effects such as the regulation of feeding, energy metabolism, and reproductive behavior.

25 Dec 2018

Scientists discover host of new and unexpected nanoparticles

Scientists from Russia and China discovered a host of new and unexpected nanoparticles and found a way to control their composition and properties the findings that break fresh ground in the use of nanoparticles.

21 Dec 2018

Calorie-labeling may change the way your brain responds to food

Seeing pictures of food with calorie information not only makes food less appetizing but it also appears to change the way your brain responds to the food, according to a Dartmouth-led study published in PLOS ONE.

21 Dec 2018

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

A recent study led by researchers in Texas A&M University's department of nutrition and food science shows how a novel regulatory mechanism serves as an important biomarker for the development of diabetes, as well as a potential therapeutic target for its prevention.

20 Dec 2018

Study: Brain connectivity network in T1D patients is different from healthy people

Patients with Type 1 Diabetes have a brain connectivity network different from the healthy people, according to a new study led by researchers of the Institute of Neurosciences and the Institute of Complex Systems of the University of Barcelona.

19 Dec 2018

Real-time neurofeedback controls Parkinson’s brainwaves

A neurofeedback system enables Parkinson’s disease patients to voluntarily control brainwaves associated with symptoms of the disorder, according to new research published in eNeuro. It remains to be determined whether such a system can provide symptom relief.

From Society for Neuroscience 19 Dec 2018

Russian scientists create hardware-information system for brain disorders treatment

A team of scientists of Ural Federal University headed by Prof. Vladimir Kublanov created a hardware-information system for brain disorders prophylaxis and treatment unrivaled both in Russia and throughout the world.

13 Dec 2018

Intellectually active lifestyle confers protection against neurodegeneration in Huntington's patients

Researchers from the Cognition and Brain Plasticity research group of the Bellvitge Biomedical Research Institute and the University of Barcelona, in collaboration with several hospitals, have discovered that an intellectually active lifestyle confers protection against neurodegeneration in people with Huntington's disease, delaying the onset of symptoms and loss of grey matter in the brain.

12 Dec 2018

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

According to some estimates, up to one in three people around the world may experience severe anxiety in their lifetime.

12 Dec 2018

Disrupted biological clock can contribute to onset of diseases, USC study shows

USC scientists report that a novel time-keeping mechanism within liver cells that helps sustain key organ tasks can contribute to diseases when its natural rhythm is disrupted.

11 Dec 2018

New study reveals yin-yang personality of dopamine

For decades, psychologists have viewed the neurotransmitter dopamine as a double-edged sword: released in the brain as a reward to train us to seek out pleasurable experiences, but also a "drug" the constant pursuit of which leads to addiction.

11 Dec 2018

Imagination can help overcome fear and anxiety-related disorders, shows study

Imagine a barking dog, a furry spider or another perceived threat and your brain and body respond much like they would if you experienced the real thing.

11 Dec 2018

Researchers explore how glial cells develop in the brain from neural precursor cells

Two types of cells are active in the brain: nerve cells and glial cells. The latter have long been regarded primarily as supportive cells, but it is increasingly recognized that they play an active role in the communication between neurons in the brain.

10 Dec 2018

Cell Nucleus News and Research

Conducting ChIP-Seq with Low Cell Numbers

Study raises hopes for new approaches to treat osteoporosis

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

Drug combination has added benefit for patients with melanoma

Researchers develop new method of analysis to map cellular locations of proteins

Researchers reveal cause of possible genetic problems in mitochondria

New mechanism may explain neurons shrinking in Huntington's disease

The role of galanin-like peptide in regulating feeding behavior and energy metabolism

Scientists discover host of new and unexpected nanoparticles

Calorie-labeling may change the way your brain responds to food

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

Study: Brain connectivity network in T1D patients is different from healthy people

Real-time neurofeedback controls Parkinson’s brainwaves

Russian scientists create hardware-information system for brain disorders treatment

Intellectually active lifestyle confers protection against neurodegeneration in Huntington's patients

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

Disrupted biological clock can contribute to onset of diseases, USC study shows

New study reveals yin-yang personality of dopamine

Imagination can help overcome fear and anxiety-related disorders, shows study

Researchers explore how glial cells develop in the brain from neural precursor cells

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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