Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

Research uncovers potential breakthrough in the understanding of tumor dormancy

Scientists at VCU Massey Cancer Center may have uncovered a primary method through which cancer cells exist undetected in an organism and received more than $1 million to investigate the potential for novel therapeutics that target and destroy cells in a specific state of tumor dormancy.

22 May 2019

New study shows how a kidney biopsy can be used to tailor treatment for lupus patients

The kidneys of patients living with systemic lupus erythematosus are often under assault, and not all those living with the disease will respond to standard treatment.

21 May 2019

Common foods linked to arterial stiffening in new metabolomics study

Researchers have identified several lifestyle factors that could cause arteries to stiffen and increase the risk of heart disease, two of which were peptides found in common foods.

7 May 2019

Form drives function in cancer proliferation, UTSW study finds

A new study finds that the protein responsible for the crawling movements of cells also drives the ability of cancer cells to grow when under stress.

6 May 2019

Deletion of ATDC gene prevents development of pancreatic cancer in mice

The action of a gene called ATDC is required for the development of pancreatic cancer, a new study finds.

2 May 2019

Blocking BRAF ubiquitination may be an effective treatment approach in melanoma

The protein BRAF is a key player in the development of many different types of cancer, including melanoma.

24 Apr 2019

Newly identified skin-gut communication helps illuminate link between food allergy and eczema

Scratching the skin triggers a series of immune responses culminating in an increased number of activated mast cells--immune cells involved in allergic reactions--in the small intestine, according to research conducted in mice.

24 Apr 2019

Phenols in purple corn may fight obesity, inflammation and diabetes, mice study shows

Scientists at the University of Illinois have developed new hybrids of purple corn containing different combinations of phytochemicals that may fight obesity, inflammation and diabetes, a new study in mice indicates.

16 Apr 2019

‘Hit-and-run’ interaction between proteins appears to be key trigger for cell death

A 'hit-and-run' interaction between two proteins could be an important trigger for cell death, according to new research from Walter and Eliza Hall Institute researchers.

10 Apr 2019

Researchers explore biological mechanisms behind obesity-cancer link

New studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers explore biological mechanisms behind obesity and its link with cancer.

1 Apr 2019

New targetable vulnerability in breast cancer cells discovered

Researchers at the University of Helsinki and Karolinska Institutet have discovered new molecular mechanisms of breast cancer cell signaling that contribute to aggressive behavior of cancer cells.

29 Mar 2019

Pediatric Cell Atlas needed for better understanding of children’s health and illnesses

Research efforts to comprehensively map adult human cells are in progress. But in a Perspective publishing March 28 in the journal Developmental Cell, researchers argue that there is a need to map children’s cells with the same level of granularity.

29 Mar 2019

Study finds novel opportunity for treating subgroup of cancer patients with MSI-H tumors

Researchers have identified a protein critical for the survival of a particular type of tumor cell, according to a study published today in eLife.

27 Mar 2019

VCU researchers home in on microRNA processing for new cancer therapies

More than a decade of research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs.

26 Mar 2019

Nervous system relies on guidance cues for neuronal axons to reach destinations

Similar to the dozens of Sherpas that guide hikers up treacherous Himalayan mountains to reach a summit, the nervous system relies on elaborate timing and location of guidance cues for neuronal axons--threadlike projections--to successfully reach their destinations in the body.

25 Mar 2019

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

22 Mar 2019

High-fructose corn syrup fuels growth of colon tumors in mice

Consuming the equivalent of one can of soda per day caused mice predisposed to colon cancer to develop larger tumors, according to a study by Weill Cornell Medicine and NewYork-Presbyterian investigators.

22 Mar 2019

Combined glucocorticoid and antioxidant therapy could benefit premature babies

Scientists at the University of Cambridge have suggested that subtle changes to the drugs administered to mothers threatened with preterm birth or to premature babies could further improve clinical treatment and help increase their safety.

21 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

New technology platform digitally counts growth factors in single cells

Whether healthy or diseased, human cells exhibit behaviors and processes that are largely dictated by growth factor molecules, which bind to receptors on the cells. For example, growth factors tell the cells to divide, move, and when to die--a process known as apoptosis.

23 Feb 2019