Low Density Lipoprotein (LDL) News and Research

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Researchers gain new insights into molecular mechanisms affected by weight gain

Until now there have been few molecular epidemiological studies regarding the effects of weight changes on metabolism in the general population. In a recent study conducted and funded within the framework of the Competence Network Obesity, researchers at the Institute of Epidemiology II at Helmholtz Zentrum München evaluated molecular data of the KORA study.

12 Mar 2015

Type 2 diabetes less common in patients with familial hypercholesterolemia

The prevalence of type 2 diabetes among 25,000 patients with familial hypercholesterolemia (a genetic disorder characterized by high low-density lipoprotein [LDL] cholesterol levels) was significantly lower than among unaffected relatives, with the prevalence varying by the type of gene mutation, according to a study in the March 10 issue of JAMA.

11 Mar 2015

Study shows that plant-based vegan diet may lower heart disease risk in obese children

Obese children who begin a low-fat, plant-based vegan diet may lower their risk of heart disease through improvements in their weight, blood pressure, body mass index, cholesterol levels, insulin sensitivity, and high-sensitivity C-reactive, according to Cleveland Clinic research published online today by The Journal of Pediatrics.

16 Feb 2015

Corn oil has greater effects on blood cholesterol than extra virgin olive oil

A study published in the January/February 2015 issue of the Journal of Clinical Lipidology indicates corn oil significantly reduces cholesterol more than extra virgin olive oil with favorable changes in both total and low-density lipoprotein (LDL) cholesterol.

31 Jan 2015

Study: Low glycemic diet does not improve insulin sensitivity or cardiovascular risk factors

Nutrition experts are continually debating the nutritional value of carbohydrate-containing foods and whether some are healthier than others. High carbohydrate foods are classified by how much they increase blood sugar; known as glycemic index. In new findings led by researchers at Brigham and Women's Hospital in Boston and Johns Hopkins University in Baltimore, researchers looked at glycemic index' effect on cardiovascular disease (CVD) and diabetes and found that low glycemic diets did not improve insulin sensitivity or cardiovascular risk factors.

16 Dec 2014

Estrogen plays key role in regulating blood pressure, LDL cholesterol levels

What makes some women more susceptible to heart disease than others? To help answer that question, researchers at Western University's Robarts Research Institute have identified that an estrogen receptor, previously shown to regulate blood pressure in women, also plays an important role in regulating low-density lipoprotein (LDL) cholesterol levels.

13 Nov 2014

TSRI research points toward new method for treating atherosclerosis

Scientists at The Scripps Research Institute have created a synthetic molecule that mimics "good" cholesterol and have shown it can reduce plaque buildup in the arteries of animal models. The molecule, taken orally, improved cholesterol in just two weeks.

10 Oct 2014

New guidelines can improve the way statin drugs prescribed to patients at cardiovascular risk

New national guidelines can improve the way statin drugs are prescribed to patients at risk for cardiovascular disease, a Yale University study has found.

27 Aug 2014

Menopause-related changes in sex hormones linked to greater risk for heart disease

As hormone levels change during the transition to menopause, the quality of a woman's cholesterol carriers degrades, leaving her at greater risk for heart disease, researchers at the University of Pittsburgh Graduate School of Public Health discovered.

28 Jun 2014

Women living with diabetes, high cholesterol less likely to reach treatment goals

Queen's University assistant professor Pendar Farahani (Department of Medicine and Department of Public Health Sciences) is advocating the use of gender-based treatment for mitigating the cardiovascular risk factors related to diabetes.

24 Jun 2014

Growth hormone deficiency may protect people from developing Type 2 diabetes, cancer

People who lack growth hormone (GH) receptors also appear to have marked insulin sensitivity that prevents them from developing diabetes and lowers their risk for cancer, despite their increased percentage of body fat, new research finds.

24 Jun 2014

New study confirms that drinking diet beverages helps people lose weight

A groundbreaking new study published today in Obesity, the journal of The Obesity Society, confirms definitively that drinking diet beverages helps people lose weight.

28 May 2014

CVD risk factors may differ between men and women with type 2 diabetes, shows study

Type 2 diabetes greatly increases a person's risk of developing cardiovascular disease (CVD). A new study showing that cardiovascular risk factors such as elevated blood pressure and cholesterol levels differ significantly between men and women is published in Diabetes Technology & Therapeutics (DTT), a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

16 May 2014

Controlling low-density lipoprotein-cholesterol levels: an interview with Jay Edelberg, M.D., Sanofi and Bill Sasiela, Ph.D., Regeneron

Lipids, primarily cholesterol and triglycerides, come from two sources: what is naturally manufactured in the liver and what comes from the intestines through the diet.

From Sanofi 7 May 2014

Johns Hopkins scientists find a way to prevent atherosclerosis

Working with mice and rabbits, Johns Hopkins scientists have found a way to block abnormal cholesterol production, transport and breakdown, successfully preventing the development of atherosclerosis, the main cause of heart attacks and strokes and the number-one cause of death among humans. The condition develops when fat builds inside blood vessels over time and renders them stiff, narrowed and hardened, greatly reducing their ability to feed oxygen-rich blood to the heart muscle and the brain.

23 Apr 2014

Findings underscore importance of universal pediatric cholesterol screening

Roughly one out of three kids screened for high cholesterol between the ages of 9 and 11 has borderline or high cholesterol, potentially placing them at greater risk for future cardiovascular disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

29 Mar 2014

Some people experience worse cholesterol levels during colder months

Cholesterol levels fluctuate based on the time of year with more unfavorable lipid profiles seen in the colder months, a trend that may be driven by related behavior changes, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Calcium and vitamin D supplements can improve cholesterol profiles in postmenopausal women

Calcium and vitamin D supplements after menopause can improve women's cholesterol profiles. And much of that effect is tied to raising vitamin D levels, finds a new study from the Women's Health Initiative just published online in Menopause, the journal of The North American Menopause Society.

6 Mar 2014

Red wine and dark chocolate taste great and have heart-healthy components

Forget the oysters and the champagne this Valentine's Day. If you want to keep your true love's heart beating strong, the real foods of love are dark chocolate and red wine, said Loyola University Health System preventive heart specialist Sara Sirna, MD.

12 Feb 2014

New study co-led by scientists sheds light on role of genes, blood lipid levels in cardiovascular health

New genetic evidence strengthens the case that one well-known type of cholesterol is a likely suspect in causing heart disease, but also casts further doubt on the causal role played by another type.

10 Feb 2014