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First Edition: Aug. 12, 2013

Today's headlines include reports about state action on the health law's implementation and other news from the health insurance marketplace.

12 Aug 2013

State highlights: Accusations of fraud or abuse in disabled, rehabilitation clinics in N.Y., Mich. and Calif.

Two and a half years ago, The New York Times published an article about abusive employees who worked for the state, detailing how few employees were fired, even after the state recommended that they lose their jobs, because of weaknesses in the arbitration process, the permissive attitude of state officials and the aggressive stance of public sector labor unions -- particularly the Civil Service Employees Association. Gov. Andrew M. Cuomo promised to change all this.

12 Aug 2013

Dopamine responses to alcohol ingestion may serve as marker of vulnerability to AUDs

There are two traits closely associated with the development of alcohol use disorders (AUDs). One is a lower subjective intoxication response, also known as a low level of response to alcohol.

12 Aug 2013

Research: Chronic cocaine use may reduce body's ability to store fat

Chronic cocaine use may reduce the body's ability to store fat, new research from the University of Cambridge suggests. The scientists found that cocaine use may cause profound metabolic changes which can result in dramatic weight gain during recovery, a distressing phenomenon that can lead to relapse.

12 Aug 2013

Adolescents who have half-siblings with different father are more likely to use drugs

Adolescents who have half-siblings with a different father are more likely to have used drugs and had sex by age 15 than those who have only full siblings. That's according to new research from Karen Benjamin Guzzo, an assistant professor of sociology at Bowling Green State University, and Cassandra Dorius, an assistant professor of human development and family studies at Iowa State University.

12 Aug 2013

Brand-name and generic drug makers take fight to states

The battle concerns state notification laws that would require pharmacists to notify doctors and patients when they substitute generic versions of drugs derived from living organisms known as biologics.

12 Aug 2013

Study of childhood epilepsies links two new genes to severe forms of disease

A genetic study of childhood epilepsies has linked two new genes to severe forms of disease and provides a novel strategy for identifying therapy targets. This study used a cutting-edge genetic technique, called exome sequencing, to search for new mutations that are not inherited.

12 Aug 2013

Scientists use nanoparticles to regulate DNA interactions in self-assembly, drug-delivery

A team of chemists in SU's Cf ollege oArts and Scientists has used a temperature-sensitive polymer to regulate DNA interactions in both a DNA-mediated assembly system and a DNA-encoded drug-delivery system.

12 Aug 2013

Researchers identify biomarkers of TB that may help in new treatments

Researchers at the University of Southampton have identified new markers of tuberculosis (TB) that may help in the development of new diagnostic tests and treatments.

12 Aug 2013

Drug-related emergency department visits increase among younger adults

A new report by the Substance Abuse and Mental Health Services Administration shows that some drug-related emergency department visits increased by 300 percent -- from 5,605 visits in 2005 to 22,949 visits in 2011. These visits, made by adults aged 18 to 34, were related to the nonmedical use of central nervous system stimulants. On average, about 30 percent of these visits also involved alcohol.

9 Aug 2013

TUM scientists decode typical protein profile of tumor cells

In what is the biggest study of its kind to date, researchers from Technische Universit-t M-nchen have identified over 10,000 different proteins in cancer cells. "Nearly all anti-tumor drugs are targeted against cellular proteins," says Prof. Bernhard K-ster, Head of the TUM Chair of Proteomics and Bioanalytics. "Identifying the proteome the protein portfolio of tumor cells increases our chances of finding new targets for drugs."

9 Aug 2013

Research suggests blocking DNA repair complex helps fight therapy-resistant leukemia

New research posted online by the Nature journal Leukemia suggests blocking part of a DNA repair complex that helps some types of leukemia resist treatment can increase the effectiveness of chemotherapy and enhance survival.

9 Aug 2013

Investigational malaria vaccine offers protection against malaria infection in healthy adults

An investigational malaria vaccine has been found to be safe, to generate an immune system response, and to offer protection against malaria infection in healthy adults, according to the results of an early-stage clinical trial published Aug. 8 in the journal Science.

9 Aug 2013

University of Surrey scientists move one step closer to find successful treatment for TB

Scientists at the University of Surrey have undertaken research into tuberculosis which could result in quicker treatment for sufferers and potentially reduce the problem of drug-resistance.

9 Aug 2013

Researchers unveil comprehensive portrait of the genome of world's first immortal cell line

A team from the University of Washington has unveiled a comprehensive portrait of the genome of the world's first immortal cell line, known as HeLa. The cell line was derived in 1951 from an aggressive cervical cancer that killed Henrietta Lacks, a 31-year-old African-American tobacco farmer and mother of five - the subject of the 2010 New York Times bestseller, The Immortal Life of Henrietta Lacks.

8 Aug 2013

Cognitive decline with age is natural part of life, OSU researchers find

If you forget where you put your car keys and you can't seem to remember things as well as you used to, the problem may well be with the GluN2B subunits in your NMDA receptors.

8 Aug 2013

ASU expert receives $1.6 million grant to advance microscopy imaging research

At Arizona State University's Biodesign Institute, Nongjian (NJ) Tao has been designing advanced microscopy methods with the ambitious aim of capturing molecular-scale phenomena in living systems. The new techniques, which combine multiple imaging modalities, are poised to revolutionize the study of biology and the development of new drugs.

8 Aug 2013

New bio-artificial "encapsulife" pancreas points to cure for diabetes

The Squash Diabetes Campaign, launched by the Georgetown University Women's Squash Team* in December 2012 and sponsored by New Generation Foundation, today announced a $125,000 grant provided by the Chicago-based Chauncey and Marion D. McCormick Family Foundation.

8 Aug 2013

Research suggests treadmill training after spinal cord injury can have positive effects on recovery

New research suggests that treadmill training soon after a spinal cord injury can have long-lasting positive effects on recovery - as long as the training is accompanied by efforts to control inflammation in the lower spinal cord.

8 Aug 2013

Research findings may give scientists a way to destroy cancerous cells

Researchers at Warwick Medical School have identified the key role played by a team of proteins in the process of mitosis. Working out how to control them may give scientists a way to destroy cancerous cells.

8 Aug 2013

Drugs News and Research

First Edition: Aug. 12, 2013

State highlights: Accusations of fraud or abuse in disabled, rehabilitation clinics in N.Y., Mich. and Calif.

Dopamine responses to alcohol ingestion may serve as marker of vulnerability to AUDs

Research: Chronic cocaine use may reduce body's ability to store fat

Adolescents who have half-siblings with different father are more likely to use drugs

Brand-name and generic drug makers take fight to states

Study of childhood epilepsies links two new genes to severe forms of disease

Scientists use nanoparticles to regulate DNA interactions in self-assembly, drug-delivery

Researchers identify biomarkers of TB that may help in new treatments

Drug-related emergency department visits increase among younger adults

TUM scientists decode typical protein profile of tumor cells

Research suggests blocking DNA repair complex helps fight therapy-resistant leukemia

Investigational malaria vaccine offers protection against malaria infection in healthy adults

University of Surrey scientists move one step closer to find successful treatment for TB

Researchers unveil comprehensive portrait of the genome of world's first immortal cell line

Cognitive decline with age is natural part of life, OSU researchers find

ASU expert receives $1.6 million grant to advance microscopy imaging research

New bio-artificial "encapsulife" pancreas points to cure for diabetes

Research suggests treadmill training after spinal cord injury can have positive effects on recovery

Research findings may give scientists a way to destroy cancerous cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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