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Study identifies seven new genetic regions associated with pulmonary fibrosis

A new genome-wide association study of more than 6,000 people has identified seven new genetic regions associated with pulmonary fibrosis. In findings published online in Nature Genetics on April 14, 2013, researchers at National Jewish Health, the University of Colorado and several other institutions found a number of genes associated with host defense, cell-cell adhesion and DNA repair, which provide clues to possible mechanisms underlying this currently untreatable disease.

20 Apr 2013

Researcher discovers additional mechanical properties of articular cartilage result in osteoarthritis

A researcher at The Feinstein Institute for Medical Research has discovered additional mechanical properties of articular cartilage, a protective cartilage on the ends of bones that wears down over time, resulting in the development of osteoarthritis.

20 Apr 2013

Long winter months impact tamoxifen treatment for breast cancer

For women diagnosed with a form of breast cancer known as estrogen receptor positive (ER+) breast cancer, tamoxifen is an essential drug used in the treatment and prevention of recurring breast cancer.

19 Apr 2013

Arthritis drug reduces dry eye disease

Dry eye disease (DED) is a common condition that causes discomfort, visual disturbance and potentially damaging ocular surface inflammation that greatly impacts a person's quality of life.

19 Apr 2013

PKC supplies Nano-Impedance Biosensor for detecting VEGF-165

Pharmaco-Kinesis Corporation, developer of a pre-commercialized smart implantable pump for localized cancer-fighting drug delivery, today announced its first commercialized offering, the first-generation Nano-Impedance Biosensor.

19 Apr 2013

Abnormal protein translation leads to Fragile X ataxia, study finds

A bizarre twist on the usual way proteins are made may explain mysterious symptoms in the grandparents of some children with mental disabilities.

19 Apr 2013

Research shows how breakdowns in DNA copying process contribute to cancer

Research led by a scientist at the University of York has thrown new light on the way breakdowns in the DNA copying process inside cells can contribute to cancer and other diseases.

19 Apr 2013

Researchers study new ways of taking advantage of caffeine's lethal effects on cancer cells

Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine's lethal effects on cancer cells-results that could one day be used to advance cancer therapies for people.

19 Apr 2013

Tel Aviv University researcher reveals the missing link between brain patterns and Alzheimer's

Evidence indicates that the accumulation of amyloid-beta proteins, which form the plaques found in the brains of Alzheimer's patients, is critical for the development of Alzheimer's disease, which impacts 5.4 million Americans.

19 Apr 2013

Three missense variants of BRCA1 gene linked to breast or ovarian cancer risk, study shows

Researchers of the hereditary cancer research group at the Bellvitge Biomedical Research Institute and the Catalan Institute of Oncology conducted a functional and structural study of seven missense variants of the BRCA1 gene concluding that three of these variants are pathogenic, linked to the risk of suffering breast or ovarian cancer.

19 Apr 2013

Research: Gene behind epilepsy syndrome could play a key role in other idiopathic epilepsies

Researchers at the University Department of Neurology at the MedUni Vienna have identified a gene behind an epilepsy syndrome, which could also play an important role in other idiopathic (genetically caused) epilepsies.

18 Apr 2013

Running or jumping may worsen cartilage damage, MIT engineers find

Osteoarthritis, which affects at least 20 percent of adults in the United States, leads to deterioration of cartilage, the rubbery tissue that prevents bones from rubbing together.

18 Apr 2013

Study highlights importance of zebrafish as a model organism for human disease research

Researchers demonstrate today that 70 per cent of protein-coding human genes are related to genes found in the zebrafish and that 84 per cent of genes known to be associated with human disease have a zebrafish counterpart.

18 Apr 2013

ARMGO Pharma gets $1 million to support ARM210 preclinical work for DMD treatment

ARMGO Pharma and the Muscular Dystrophy Association today announced that $1 Million has been awarded for preclinical work in support of an Investigational New Drug application with the U.S. Food and Drug Administration for ARM210, a novel, orally available, small-molecule Rycal drug that has potential as a treatment for Duchenne muscular dystrophy.

18 Apr 2013

CRISPR helps some bacteria evade mammalian immune system

CRISPR, a system of genes that bacteria use to defend themselves against viruses, has been found to be involved in helping some bacteria evade the mammalian immune system.

18 Apr 2013

NCI researchers overcome major impediment to development of effective stem cell therapies

Scientists have overcome a major impediment to the development of effective stem cell therapies by studying mice that lack CD47, a protein found on the surface of both healthy and cancer cells.

18 Apr 2013

Scientists reveal that stem cells, tissue-specific cells can be grown from mature mammalian cells

tem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the National Institutes of Health.

18 Apr 2013

UTHealth neuroscientists demonstrate new strategy to overcome memory deficits

Neuroscientists at The University of Texas Health Science Center at Houston have taken a major step in their efforts to help people with memory loss tied to brain disorders such as Alzheimer's disease.

18 Apr 2013

Findings hold promise for development of therapies to fight different viral infections

The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable viruses to enter cells.

18 Apr 2013

UTMB researchers identify protein that can interfere with the brain's response to leptin

Ever since the appetite-regulation hormone called leptin was discovered in 1994, scientists have sought to understand the mechanisms that control its action. It was known that leptin was made by fat cells, reduced appetite and interacted with insulin , but the precise molecular details of its function -details that might enable the creation of a new treatment for obesity - remained elusive.

18 Apr 2013

Protein C News and Research

Study identifies seven new genetic regions associated with pulmonary fibrosis

Researcher discovers additional mechanical properties of articular cartilage result in osteoarthritis

Long winter months impact tamoxifen treatment for breast cancer

Arthritis drug reduces dry eye disease

PKC supplies Nano-Impedance Biosensor for detecting VEGF-165

Abnormal protein translation leads to Fragile X ataxia, study finds

Research shows how breakdowns in DNA copying process contribute to cancer

Researchers study new ways of taking advantage of caffeine's lethal effects on cancer cells

Tel Aviv University researcher reveals the missing link between brain patterns and Alzheimer's

Three missense variants of BRCA1 gene linked to breast or ovarian cancer risk, study shows

Research: Gene behind epilepsy syndrome could play a key role in other idiopathic epilepsies

Running or jumping may worsen cartilage damage, MIT engineers find

Study highlights importance of zebrafish as a model organism for human disease research

ARMGO Pharma gets $1 million to support ARM210 preclinical work for DMD treatment

CRISPR helps some bacteria evade mammalian immune system

NCI researchers overcome major impediment to development of effective stem cell therapies

Scientists reveal that stem cells, tissue-specific cells can be grown from mature mammalian cells

UTHealth neuroscientists demonstrate new strategy to overcome memory deficits

Findings hold promise for development of therapies to fight different viral infections

UTMB researchers identify protein that can interfere with the brain's response to leptin

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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