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Physicians prescribe strongest antibiotics capable of killing multiple kinds of bacteria

When U.S. physicians prescribe antibiotics, more than 60 percent of the time they choose some of the strongest types of antibiotics, referred to as "broad spectrum," which are capable of killing multiple kinds of bacteria, University of Utah researchers show in a new study.

2 Aug 2013

FDA promise to "reboot" antibiotic development rules to combat rise in resistance falls short

The rise of antibiotic resistance among hospital-acquired infections is greater than the Centers for Disease Control and Prevention found in its 2008 analysis, according to an ahead-of-print article in the journal, Antimicrobial Agents and Chemotherapy.

2 Aug 2013

Protein linked to learning induces cocaine addiction, say researchers

A team of researchers says it has solved the longstanding puzzle of why a key protein linked to learning is also needed to become addicted to cocaine. Results of the study, published in the Aug. 1 issue of the journal Cell, describe how the learning-related protein works with other proteins to forge new pathways in the brain in response to a drug-induced rush of the “pleasure” molecule dopamine.

2 Aug 2013

Study offers new hope for treatment of diffuse large B-cell lymphoma

Researchers have discovered how an experimental drug is capable of completely eradicating human lymphoma in mice after just five doses. The study, led by researchers at Weill Cornell Medical College, sets the stage for testing the drug in clinical trials of diffuse large B-cell lymphoma, the most common subtype of non-Hodgkin lymphoma, itself the seventh most frequently diagnosed cancer in the U.S.

2 Aug 2013

ICSD, SAGE launch journal that provides information on drugs to public and professionals

SAGE and the Independent Scientific Committee on Drugs (ICSD) today announced the launch of Drug Science, Policy and Law, an online journal supporting the ICSD's goals of providing accessible information on drugs to the public and professionals.

2 Aug 2013

Cancer biomarker tests undervalued by doctors and patients, authors say

There's a major roadblock to creating personalized cancer care. Doctors need a way to target treatments to patients most likely to benefit and avoid treating those who will not. Tumor biomarker tests can help do this.

2 Aug 2013

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Blocking dietary sugar and its activity in tumor cells may reduce cancer risk and progression, according to researchers from the Icahn School of Medicine. The study, conducted in fruit flies and published in the journal Cell, provides insight as to why metabolism-related diseases such as diabetes or obesity are associated with certain types of cancer, including pancreatic, breast, liver, and colon cancers

2 Aug 2013

Scientists prevent cell sleep to reduce chance of tumor recurrence

An international research team led by University of Pittsburgh Cancer Institute (UPCI) scientists discovered that by preventing cancer cells from entering a state of cellular sleep, cancer drugs are more effective, and there is a lower chance of cancer recurrence.

2 Aug 2013

Lawsuit alleges hospital operators paid kickbacks, defrauded Medicaid

A whistleblower says two hospital operators paid clinics to direct to their hospitals pregnant mothers living in the U.S. illegally.

2 Aug 2013

Trace substance in sugar improves muscle regeneration in mouse model with muscular dystrophy

A trace substance in caramelized sugar, when purified and given in appropriate doses, improves muscle regeneration in a mouse model of Duchenne muscular dystrophy. The findings are published today, Aug. 1, in the journal Skeletal Muscle.

2 Aug 2013

Researchers show that JQ1 drug can block molecular pathway responsible for heart failure

Researchers from Case Western Reserve University School of Medicine and the Dana-Farber Cancer Institute have made a fundamental discovery relevant to the understanding and treatment of heart failure - a leading cause of death worldwide. The team discovered a new molecular pathway responsible for causing heart failure and showed that a first-in-class prototype drug, JQ1, blocks this pathway to protect the heart from damage.

2 Aug 2013

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have successfully combined cellular therapy and gene therapy in a mouse model system to develop a viable treatment strategy for breast cancer that has metastasized, or spread, to the patient's brain.

2 Aug 2013

"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

Bethesda, MD-Japanese researchers have made a new step toward understanding why-and how to stop-runaway inflammation for both chronic obstructive pulmonary disorder (COPD) and allergic asthma. In a new report appearing in the August 2013 issue of The FASEB Journal scientists show that two receptors of an inflammatory molecule, called "leukotriene B4," play opposing roles in turning inflammation on and off for allergic asthma and COPD.

2 Aug 2013

SGR repeal measure moves to full House consideration

Some medical societies, which support repealing Medicare's Sustainable Growth Rate formula, are expressing concern that a bill won't be signed into law before a scheduled 25 percent reduction in Medicare physician payment takes effect. Meanwhile, members of the Senate Finance Committee are working on their own plan.

2 Aug 2013

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

The most commonly diagnosed form of breast cancer, termed estrogen receptor positive or ER+, accounts for the largest percentage of breast cancer deaths each year. Research by scientists at the HudsonAlpha Institute for Biotechnology and the University of Alabama at Birmingham Comprehensive Cancer Center aims to provide physicians a more targeted approach to treating ER+ breast cancer.

2 Aug 2013

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

Cancer immunotherapy aims to recruit a patient’s immune system to recognize cancer as foreign and dangerous and to remove it from the body, as it would an infection.

1 Aug 2013

Cambridge scientists identify molecular 'on/off' switch in malignant germ cell tumours

Cambridge scientists have identified an 'on/off' switch in a type of cancer which typically occurs in the testes and ovaries called 'malignant germ cell tumours'. The research was published today, 01 August, in the journal Cancer Research.

1 Aug 2013

Researchers identify novel approach to enhance tissue repair and organ regeneration

Because most human tissues do not regenerate spontaneously, advances in tissue repair and organ regeneration could benefit many patients with a wide variety of medical conditions.

1 Aug 2013

Experts say action needed urgently to ensure India's new policy does not backfire

In an editorial published online today in BMJ, Johns Hopkins bioethicist Jeremy Sugarman and other experts warn that action is urgently needed to deal with possible unintended consequences of India's new policy protecting research participants.

1 Aug 2013

New approach could provide alternative treatment for chemotherapy-resistant breast cancer

A new way to target a breast cancer cells' appetite for over-indulging in sugar, that could provide an alternative treatment for chemotherapy resistant breast cancer, is being developed by Breast Cancer Campaign scientists at the University of Southampton.

1 Aug 2013

Drugs News and Research

Physicians prescribe strongest antibiotics capable of killing multiple kinds of bacteria

FDA promise to "reboot" antibiotic development rules to combat rise in resistance falls short

Protein linked to learning induces cocaine addiction, say researchers

Study offers new hope for treatment of diffuse large B-cell lymphoma

ICSD, SAGE launch journal that provides information on drugs to public and professionals

Cancer biomarker tests undervalued by doctors and patients, authors say

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Scientists prevent cell sleep to reduce chance of tumor recurrence

Lawsuit alleges hospital operators paid kickbacks, defrauded Medicaid

Trace substance in sugar improves muscle regeneration in mouse model with muscular dystrophy

Researchers show that JQ1 drug can block molecular pathway responsible for heart failure

UCLA researchers develop treatment approach for breast cancer metastasized to brain

"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

SGR repeal measure moves to full House consideration

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

Cambridge scientists identify molecular 'on/off' switch in malignant germ cell tumours

Researchers identify novel approach to enhance tissue repair and organ regeneration

Experts say action needed urgently to ensure India's new policy does not backfire

New approach could provide alternative treatment for chemotherapy-resistant breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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