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Elevated fat and cholesterol levels in diet may play a role in breast cancer development

Elevated fat and cholesterol levels found in a typical American-style diet play an important role in the growth and spread of breast cancer, say researchers at the Kimmel Cancer Center at Jefferson.

7 Jan 2011

Administration of therapeutic hypothermia for TBI should depend on clinical condition of individual patients

Lowering the body temperature of patients soon after they have suffered a severe brain injury may reduce neurologic complications and improve outcomes. The safety of therapeutic hypothermia for traumatic brain injury (TBI) has been demonstrated in national studies. According to a Roundtable Discussion of renowned experts in the field, when and how it is administered should depend on the clinical condition of individual patients.

5 Jan 2011

Dutch scientists provide new insights into intestinal cancer through plant study

Dutch scientists have gained important new insights into intestinal cancer from studying a plant. The disease is called Peutz-Jeghers Syndrome, a hereditary disorder where people develop intestinal polyps that turn into malignant tumors.

5 Jan 2011

CDK1 protein deactivates EZH2 enzyme that causes cancer spread

By sticking a chemical group to it at a specific site, a protein arrests an enzyme that may worsen and spread cancer, an international research team led by scientists at The University of Texas MD Anderson Cancer Center reports in the January issue of Nature Cell Biology.

4 Jan 2011

Fondation Leducq awards Penn Medicine researcher $6M grant for cardiovascular disease study

An international team of researchers led by Daniel J. Rader, MD, associate director of Penn Medicine's Institute for Translational Medicine and Therapeutics, has received a $6 million grant from the Paris-based Fondation Leducq to study the molecular genetics of atherosclerotic cardiovascular disease. The team's proposal, "Molecular Mechanisms of Novel Genes Associated with Plasma Lipids and Cardiovascular Disease," was selected to receive the award through the Fondation's Transatlantic Networks of Excellence Program.

4 Jan 2011

New findings may solve mystery about how starvation hormone affects multiple biological systems

New findings by UT Southwestern Medical Center researchers may solve a 17-year-old mystery about how the so-called "starvation hormone" affects multiple biological systems, including preventing insulin sensitivity and promoting cell survival.

27 Dec 2010

AMPK activates autophagy by activating ATG1 enzyme

Researchers at the Salk Institute for Biological Studies have discovered how AMPK, a metabolic master switch that springs into gear when cells run low on energy, revs up a cellular recycling program to free up essential molecular building blocks in times of need.

24 Dec 2010

Sequestering GSK3 enzyme leads to stabilization of proteins in cells

The cell signaling pathway known as Wnt, commonly activated in cancers, causes internal membranes within a healthy cell to imprison an enzyme that is vital in degrading proteins, preventing the enzyme from doing its job and affecting the stability of many proteins within the cell, researchers at UCLA's Jonsson Comprehensive Cancer Center have found.

24 Dec 2010

BioTime enters MTA with UC to make research-grade hES cell lines

BioTime, Inc. today announced a material transfer agreement (MTA) with the University of California (UC) system to make five research-grade human embryonic stem (hES) cell lines available to UC system researchers. These lines are genetically identical to a bank of GMP-compliant hES cell lines that will be made available to California-based researchers under a recent agreement between BioTime and the California Institute for Regenerative Medicine (CIRM).

23 Dec 2010

Molecular breakdown of Bicoid protein vital for normal patterning of fruit fly's offspring

Using fruit flies as a model to study embryo formation, scientists report in Nature Cell Biology that molecular breakdown of a protein called Bicoid is vital to normal head-to-tail patterning of the insect's offspring.

22 Dec 2010

Time magazine declares NYSCF member as 2010 "Person who Matters" for innovative stem cell research

The New York Stem Cell Foundation extends congratulations to Derrick Rossi, PhD, a member of the inaugural class of NYSCF-Robertson Investigators, who was named one of Time Magazine's 2010 "People Who Mattered" in the December 27, 2010 Person of the Year Issue.

22 Dec 2010

People with type 1 diabetes could grow their own insulin-producing cells, say researchers

At the annual meeting of the American Society for Cell Biology last week in Philadelphia, researchers from Georgetown University Medical Center in Washington, D.C., announced that it may be possible for people with type 1 diabetes to grow their own insulin-producing cells, a breakthrough that could lead to a cure for the disease.

22 Dec 2010

Precision BioSciences receive $3 million to develop DNE technology

Precision BioSciences, today announced that it has been awarded over $3 million across four government grants. These grants were each awarded to Precision during the 4th Quarter of 2010 and came from the National Institute of Standards and Technology, the Treasury Department, the National Institute of Health, and the State of North Carolina.

16 Dec 2010

Scientists demonstrate similarity between individual development and phylogeny in level of gene expression

Similarities in the embryonic development of various animal species are also found at molecular level. The astonishing similarity in the appearance of embryos from different animal species was observed as far back as the 19th century by scientists such as Karl von Baer, Charles Darwin and Ernst Haeckel.

16 Dec 2010

African sleeping sickness parasite's previously unrecognized extreme social behavior discovered

Long considered a freewheeling loner, the Trypanosoma brucei parasite responsible for African sleeping sickness has revealed a totally unexpected social side, opening a potential chink in the behavioral armor of this and other supposedly solitary human parasites, according to research presented at the American Society for Cell Biology's 50th Annual Meeting in Philadelphia.

15 Dec 2010

Cell Biosciences receives US Patent for NanoPro assay technology

Cell Biosciences, Inc. today announced the issuance of Patent No. 7,846,676 for "Methods and Devices for Analyte Detection" by the United States Patent and Trademark Office.

15 Dec 2010

New hypothesis emphasizes the value of anti-inflammatory approaches to prevent Alzheimer's disease

Karl Herrup thinks that the national research effort to understand Alzheimer-s disease has gone about as far as it can go with its current theories.

15 Dec 2010

Over expression of transcription factor improves neurological function in HD transgenic mice models

Over expressing a transcription factor that promotes the increase in number of mitochondria greatly improves the neurological function of transgenic mice models for Huntington's disease, researchers today told the American Society of Cell Biology's 50th Annual Meeting in Philadelphia.

15 Dec 2010

Roche launches new xCELLigence System RTCA HT Instrument

The new xCELLigence System RTCA HT Instrument from Roche Diagnostics rounds out the company's portfolio in real-time cell analysis with a high-throughput product. The new instrument merges the power and flexibility of xCELLigence System technology with high-throughput analyses and workflows for automated screening applications.

From Roche Sequencing and Life Science 14 Dec 2010

University of Utrecht orders for Bruker 527 GHz Solid State DNP-NMR system

Bruker announces the first order for a novel and unique 527 GHz Solid State DNP-NMR system, based on an ultra-high field NMR system. Dynamic Nuclear Polarization (DNP) has been shown to greatly increase solid-state NMR sensitivity for numerous bio-solids and advanced materials research applications.

13 Dec 2010

Cell Biology News and Research

Elevated fat and cholesterol levels in diet may play a role in breast cancer development

Administration of therapeutic hypothermia for TBI should depend on clinical condition of individual patients

Dutch scientists provide new insights into intestinal cancer through plant study

CDK1 protein deactivates EZH2 enzyme that causes cancer spread

Fondation Leducq awards Penn Medicine researcher $6M grant for cardiovascular disease study

New findings may solve mystery about how starvation hormone affects multiple biological systems

AMPK activates autophagy by activating ATG1 enzyme

Sequestering GSK3 enzyme leads to stabilization of proteins in cells

BioTime enters MTA with UC to make research-grade hES cell lines

Molecular breakdown of Bicoid protein vital for normal patterning of fruit fly's offspring

Time magazine declares NYSCF member as 2010 "Person who Matters" for innovative stem cell research

People with type 1 diabetes could grow their own insulin-producing cells, say researchers

Precision BioSciences receive $3 million to develop DNE technology

Scientists demonstrate similarity between individual development and phylogeny in level of gene expression

African sleeping sickness parasite's previously unrecognized extreme social behavior discovered

Cell Biosciences receives US Patent for NanoPro assay technology

New hypothesis emphasizes the value of anti-inflammatory approaches to prevent Alzheimer's disease

Over expression of transcription factor improves neurological function in HD transgenic mice models

Roche launches new xCELLigence System RTCA HT Instrument

University of Utrecht orders for Bruker 527 GHz Solid State DNP-NMR system

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