Endocrine News and Research

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Breast MRI spots other cancers, may alter treatment plan

In about 20 percent of women with breast cancer who plan to undergo a lumpectomy, breast magnetic resonance imaging reveals important diagnostic information that alters their treatment plan, University of Florida surgeons reported today (Dec. 5).

5 Dec 2007

Endocrine Society urges Congress to protect patient access to dual X-ray absorptiometry

The Endocrine Society strongly urges Congress to protect patient access to DXA (dual X-ray absorptiometry) - the leading diagnostic tool for the early detection and management of osteoporosis.

27 Nov 2007

Binge drinking by adolescents increases long-term risk for heart disease

New research into lifelong alcohol consumption reveals that heavy binge drinking by adolescents and young adults is associated with increased long-term risk for heart disease, high blood pressure, type 2 diabetes, and other metabolic disorders.

21 Nov 2007

NewYork-Presbyterian/Weill Cornell opens new section of general surgery called Gastrointestinal Metabolic Surgery

Opening the doors to one of the first academic medical program dedicated to surgical treatment of type 2 diabetes, NewYork-Presbyterian Hospital/Weill Cornell Medical Center has created a new section of General Surgery called Gastrointestinal Metabolic Surgery.

19 Nov 2007

Low doses of arsenic disrupt activity of development hormone

A team of Dartmouth Medical School (DMS) researchers has determined that low doses of arsenic disrupt the activity of a hormone critical in development. The finding is further evidence that arsenic at low doses (at levels found in U.S. drinking water in some areas) can be harmful.

15 Nov 2007

FDA adds warning for heart attacks to type 2 diabetes drug Avandia

The U.S. Food and Drug Administration announced today that the manufacturer of Avandia (rosiglitazone), a drug used to treat type 2 diabetes, has agreed to add new information to the existing boxed warning in the drug's labeling about potential increased risk for heart attacks.

14 Nov 2007

Trial looks at ability of insulin to limit heart-tissue damage during a heart attack

The ability of insulin to limit heart-tissue damage during a heart attack will be tested in a landmark clinical trial led by Paresh Dandona, M.D., Ph.D., University at Buffalo Distinguished Professor in the departments of Medicine and Pharmacology and Toxicology in the UB School of Medicine and Biomedical Sciences.

13 Nov 2007

Overeating alters the core mechanism of the body clock

Our body's 24-hour internal clock, or circadian clock, regulates the time we go to sleep, wake up and become hungry as well as the daily rhythms of many metabolic functions.

6 Nov 2007

Panzem (2-methoxyestradiol ) drug a possible candidate for breast cancer treatment

A Mayo Clinic study of a drug that has shown promise in treating sarcoma, lung and brain cancers, demonstrates that the drug may also be effective in treating breast cancer, in particular the spread of breast cancer.

2 Nov 2007

Government restrictions on weight loss surgeries limit access for poor, underinsured patients

Thresholds limiting bariatric surgeries to high-volume centers disproportionately restrict access for poor and underinsured patients, populations which are among the most in need of them, an analysis led by UT Southwestern Medical Center researchers shows.

30 Oct 2007

Carbamazepine and valproate may cause sexual disorders

The use of antiepileptic drugs (AEDs) can lead to decreased fertility and increased incidence of reproductive endocrine disorders in both men and women.

24 Oct 2007

Lilly and MacroGenics to develop and commercialize teplizumab

Eli Lilly and Company and MacroGenics, Inc. have announced that the two companies have entered into a global strategic alliance to develop and commercialize teplizumab, a humanized anti-CD3 monoclonal antibody, as well as other potential next generation anti-CD3 molecules for use in the treatment of autoimmune diseases.

19 Oct 2007

Study identifies pathway required for normal reproductive development

Massachusetts General Hospital (MGH) clinical researchers, in collaboration with basic scientists from the University of California, Irvine (UC Irvine) have identified a new molecular pathway required for normal development of the reproductive, olfactory and circadian systems in both humans and mice.

17 Oct 2007

Low levels of testosterone may increase risk of death in older men

Older men with low levels of testosterone may have an increased long-term risk of death compared to men with normal testosterone, according to a new study accepted for publication in the Journal of Clinical Endocrinology & Metabolism (JCEM) .

16 Oct 2007

Blood levels of progesterone may impact blood vessel function

Blood levels of progesterone, a major female sex hormone, may play an important role in modifying vascular function in postmenopausal women, according to a new study accepted for publication in the Journal of Clinical Endocrinology & Metabolism (JCEM).

16 Oct 2007

Stress is a contributing factor in human disease

In a review of the scientific literature on the relationship between stress and disease, Carnegie Mellon University psychologist Sheldon Cohen has found that stress is a contributing factor in human disease, and in particular depression, cardiovascular disease and HIV/AIDS.

10 Oct 2007

Hormones through Life conference

The Endocrine Society will present a panel of leading physicians and researchers for a half-day seminar/workshop titled "Hormones through Life."

8 Oct 2007

Even mildly underactive thyroid doubles risk of heart conditions

Individuals with subclinical hypothyroidism - a mildly underactive thyroid only detectable by a blood test - are twice as likely to develop heart failure, compared to those with normal thyroid levels, according to a new study presented on Thursday, Oct. 4, at the 78th Annual Meeting of the American Thyroid Association (ATA) in New York.

4 Oct 2007

Low doses of a red wine ingredient resveratrol fights diabetes in mice

A chemical found in the skins of red grapes and in red wine can improve the sensitivity of mice to the hormone insulin, according to a report in the October issue of Cell Metabolism, a Cell Press publication.

3 Oct 2007

Low birth weight children may be at a greater risk of stress-related health problems as adults

Findings from this study show that low birth weight (below the 10th percentile) can lead later in life to low concentrations of cortisol, a hormone that regulates stress response by adjusting blood pressure and blood sugar levels.

27 Sep 2007