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Tracking BA.2.12.1 🦠 by partial ORF1ab gene 🧬 target failure (pOGTF)

Scientists from the United States have recently identified a novel approach to rapidly and accurately detect the omicron BA.2.12.1 sub-lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples.

2 May 2022

Longitudinal and proteome-wide analysis of antibodies in COVID-19 patients using a SARS-CoV-2 proteome microarray

The first longitudinal proteome-wide analysis of antibodies in COVID-19 patients has been performed by researchers from the Beijing Institute of Microbiology and Epidemiology and published in the Journal of Advanced Research.

2 May 2022

Study finds 67% of individuals with long COVID are developing dysautonomia

In a recent study posted to the medRxiv* preprint server, researchers analyzed the traits of autonomic symptom burden in long coronavirus disease (COVID).

1 May 2022

High-frequency spinal cord stimulation proves to be more effective at improving perceived pain reduction

Spinal cord stimulation (SCS) for chronic pain involves delivering low levels of electricity directly into the spinal cord using an implanted device, which modifies or blocks nerve activity to minimize the sensation of pain reaching the brain.

28 Apr 2022

Lower urinary tract symptoms associated with mortality risk in older men

For men in their fifties and older, moderate to severe lower urinary tract symptoms (LUTS) such as incontinence and frequent nighttime urination (nocturia) are associated with an increased risk of death during long-term follow-up, suggests a Finnish study in The Journal of Urology, an Official Journal of the American Urological Association.

27 Apr 2022

Residents' health improves after switch to electric buses

University of Gothenburg The health of residents living alongside a bus route in Gothenburg, Sweden, became considerably better when hybrid buses were replaced by buses fully powered by electricity.

27 Apr 2022

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Researchers utilized a CRISPR/Cas9 system to evaluate the usage of tRNA by deleting two tRNA genes from the genomes of hyper hepatocellular carcinoma and human near-haploid chronic myeloid leukemia cells.

27 Apr 2022

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

In a study published in Cells, researchers have been investigating the effects of this extract for use against COVID-19.

27 Apr 2022

Characteristics of viral infection super-spreaders

Researchers evaluated whether certain super-spreaders transmit viral infection better and the impacts of individual variance in epidemiological characteristics.

26 Apr 2022

Scientists discover how SARS-CoV-2 activates platelets

In a recent study published in the Blood Advances journal, the researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on platelet activation.

25 Apr 2022

COVID-19 vaccine can elicit a distinct T cell-dominant immune-mediated hepatitis

In a recent study published in the Journal of Hepatology, researchers reported that the coronavirus disease 2019 (COVID-19) vaccination could elicit a distinct T cell-dominant immune-mediated hepatitis.

25 Apr 2022

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

The development of the anti-cancer immunotherapy drugs called immune checkpoint inhibitors has improved treatment for many cancer patients, but patients with mucosal melanomas - melanomas that occur not on the skin but in the mucous membranes in the head, neck, eyes, respiratory tract, and genitourinary region - are particularly resistant to immune checkpoint inhibitors for reasons researchers don't fully understand.

25 Apr 2022

Frequency News and Research

Tracking BA.2.12.1 🦠 by partial ORF1ab gene 🧬 target failure (pOGTF)

Longitudinal and proteome-wide analysis of antibodies in COVID-19 patients using a SARS-CoV-2 proteome microarray

Study finds 67% of individuals with long COVID are developing dysautonomia

High-frequency spinal cord stimulation proves to be more effective at improving perceived pain reduction

Lower urinary tract symptoms associated with mortality risk in older men

Residents' health improves after switch to electric buses

CRISPR/Cas9 deletions induce adverse on-target genomic effects

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

Characteristics of viral infection super-spreaders

Scientists discover how SARS-CoV-2 activates platelets

COVID-19 vaccine can elicit a distinct T cell-dominant immune-mediated hepatitis

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

Treating COVID-19 using monoclonal antibodies during pregnancy

Study reports increased numbers of SARS-CoV-2-reactive T cells in individuals who were HCoV-reactive

Correlations between SARS-CoV-2 outcomes and cancer

Study shows safety, feasibility of intranasal milk therapy for infants with intraventricular hemorrhage

Study describes the impact of COVID-19 pandemic on pediatric primary care mental health visits

Study demonstrates increased incidence of SARS-CoV-2 Omicron breakthrough infection in cancer patients

Continual genomic surveillance in Africa provides insights into evolving SARS-CoV-2 pandemic

Rhinovirus the main virus co-circulating with SARS-CoV-2 in children

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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