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Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

Statins, a class of cholesterol-lowering drugs found in millions of medicine cabinets, may help treat Rett Syndrome, according to a study published today in Nature Genetics. The Rett Syndrome Research Trust (RSRT) funded this work with generous support from the Rett Syndrome Research Trust UK and Rett Syndrome Research & Treatment Foundation.

30 Jul 2013

Hope for treatment of childhood infections may come straight from the gut: Therapeutic poop

Call it therapeutic poop, if you will, but the best hope yet for an effective treatment of childhood infections with the drug-resistant bacterium C. difficile may come straight from the gut, according to recent research.

30 Jul 2013

Researchers discover solution to long-standing medical mystery in Huntington's disease

Researchers at McMaster University have discovered a solution to a long-standing medical mystery in Huntington's disease (HD). HD is a brain disease that can affect 1 in about 7,000 people in mid-life, causing an increasing loss of brain cells at the centre of the brain.

30 Jul 2013

Genistein derived from soybeans shows promise in inhibiting HIV infection

A compound found in soybeans may become an effective HIV treatment without the drug resistance issues faced by current therapies, according to new research by George Mason University researchers.

30 Jul 2013

Joints of children with chronic inflammatory arthritis contain premature aging of immune cells

The joints of children with the most common form of chronic inflammatory arthritis contain immune cells that resemble those of 90-year-olds, according to a new study led by researchers at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine.

30 Jul 2013

FDA approves Rebiotix's IND application to begin RBX2660 Phase 2 study for recurrent CDI

Rebiotix Inc. announced today that the U.S. Food and Drug Administration has approved the company's Investigational New Drug application to begin the Phase 2 clinical study of RBX2660 for the treatment of recurrent Clostridium difficile infection.

30 Jul 2013

Young Swiss men understand risks of cannabis consumption

91 percent of on average 20-year-old Swiss men drink alcohol, almost half of whom drink six beverages or more in a row and are thus at-risk consumers. 44 percent of Swiss men smoke tobacco, the majority of whom are at-risk consumers - they smoke at least once a day. 36 percent of young adults smoke cannabis, whereby over half are at-risk consumers, using the drug at least twice a week.

29 Jul 2013

Research: Lymph nodes provide correct breast cancer prognosis

After a breast cancer operation, the removed tumour is always examined, as its subtype can provide an indication of how aggressive the disease is. The patient's lymph nodes are not analysed in the same way.

29 Jul 2013

Technique for developing more targeted drugs using molecular "robots"

Many drugs such as agents for cancer or autoimmune diseases have nasty side effects because while they kill disease-causing cells, they also affect healthy cells. Now a new study has demonstrated a technique for developing more targeted drugs, by using molecular "robots" to hone in on more specific populations of cells.

29 Jul 2013

Research shows that people are remaining healthier later in life

A new study, conducted by David Cutler, the Otto Eckstein Professor of Applied Economics, shows that, even as life expectancy has increased over the past two decades, people have become increasingly healthier later in life.

29 Jul 2013

Viewpoints: Doctors' sway over Medicare pay; hospital rankings not all they seem; legal immigrants' health needs overlooked

Reporters Peter Whoriskey and Dan Keating have opened Post readers' eyes to the fact that Medicare pays for physician services - a $69.6 billion item in 2012 - according to an arcane and little-known price list, over which doctors themselves exercise considerable and less-than-totally-transparent influence (7/24).

26 Jul 2013

IGTP, UAB discover first genetic biomarker to detect Lewy body dementia

The Germans Trias i Pujol Health Sciences Research Institute and the Universitat Autònoma de Barcelona have discovered the first genetic biomarker to detect Lewy body dementia, a disease that can be confused with Alzheimer's.

26 Jul 2013

State highlights: D.C. to use cash reserves to pay Medicaid providers off; Texas, Planned Parenthood reach overbilling settlement; Veteran health centers at colleges

How do you spend $48 million in unbudgeted taxpayer money without getting an OK from elected lawmakers? In the District of Columbia, there's pretty much only one way, and that's the way Mayor Vincent C. Gray is proposing to settle a high-stakes dispute with D.C. Chartered Health Plan. Gray spokesman Pedro Ribeiro confirmed Wednesday that the plan is to pay the District's share of the settlement -- a little over $35 million, with federal Medicaid dollars accounting for the rest -- out of the city's contingency cash reserve (DeBonis, 7/24).

26 Jul 2013

Weekend reading: The mystery of some innovations that are slow to be accepted; myths about the obesity crisis

Why do some innovations spread so swiftly and others so slowly? Consider the very different trajectories of surgical anesthesia and antiseptics. ... On October 16, 1846, at Massachusetts General Hospital, Morton administered his gas through an inhaler in the mouth of a young man undergoing the excision of a tumor in his jaw. ... By February, anesthesia had been used in almost all the capitals of Europe, and by June in most regions of the world.

26 Jul 2013

FDA grants orphan-drug designation for Ligand’s Captisol-enabled Topiramate Injection

Ligand Pharmaceuticals Incorporated announced that the U.S. Food and Drug Administration (FDA) has granted orphan-drug designation for its proprietary Captisol-enabled Topiramate Injection for the treatment of partial onset or primary generalized tonic-clonic seizures in hospitalized epilepsy patients who are unable to take oral topiramate.

26 Jul 2013

Updated CVD risk audit to help GPs optimise patient management is now available online

With cardiovascular disease (CVD) causing a third of all deaths in Australia, NPS MedicineWise is encouraging GPs to stay up to date with their knowledge about CVD risk assessment and therapy.

26 Jul 2013

Finding could aid in delivering personalized cancer medicine based on individual's genetics

Scientists at the Princess Margaret Cancer Centre have discovered a function of the tumor suppressor gene PTEN that helps explain why certain promising therapies fail in many cancer patients, a finding that could aid in delivering tailored, personalized cancer medicine based on an individual's genetics.

26 Jul 2013

Miriam researcher calls for new strategies to better manage, improve treatment for HCV infection

A Miriam Hospital researcher has joined forces with international colleagues to call for new strategies to better manage and improve assessment and treatment for hepatitis C (HCV) infection in individuals who inject drugs.

26 Jul 2013

Supporting cells in the inner ear can help repair damaged sensory hair cells, say researchers

Researchers have found in mice that supporting cells in the inner ear, once thought to serve only a structural role, can actively help repair damaged sensory hair cells, the functional cells that turn vibrations into the electrical signals that the brain recognizes as sound.

26 Jul 2013

Zydus, IDRI partner to develop visceral leishmaniasis vaccine candidate

In a unique partnership, Zydus, India's fourth largest healthcare group and an innovation-led global healthcare provider, and IDRI, a Seattle-based non-profit research and product development organization, announced today they are collaborating on the production and clinical development of IDRI's visceral leishmaniasis vaccine candidate, designed to prevent the deadly parasitic disease.

26 Jul 2013

Drugs News and Research

Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

Hope for treatment of childhood infections may come straight from the gut: Therapeutic poop

Researchers discover solution to long-standing medical mystery in Huntington's disease

Genistein derived from soybeans shows promise in inhibiting HIV infection

Joints of children with chronic inflammatory arthritis contain premature aging of immune cells

FDA approves Rebiotix's IND application to begin RBX2660 Phase 2 study for recurrent CDI

Young Swiss men understand risks of cannabis consumption

Research: Lymph nodes provide correct breast cancer prognosis

Technique for developing more targeted drugs using molecular "robots"

Research shows that people are remaining healthier later in life

Viewpoints: Doctors' sway over Medicare pay; hospital rankings not all they seem; legal immigrants' health needs overlooked

IGTP, UAB discover first genetic biomarker to detect Lewy body dementia

State highlights: D.C. to use cash reserves to pay Medicaid providers off; Texas, Planned Parenthood reach overbilling settlement; Veteran health centers at colleges

Weekend reading: The mystery of some innovations that are slow to be accepted; myths about the obesity crisis

FDA grants orphan-drug designation for Ligand’s Captisol-enabled Topiramate Injection

Updated CVD risk audit to help GPs optimise patient management is now available online

Finding could aid in delivering personalized cancer medicine based on individual's genetics

Miriam researcher calls for new strategies to better manage, improve treatment for HCV infection

Supporting cells in the inner ear can help repair damaged sensory hair cells, say researchers

Zydus, IDRI partner to develop visceral leishmaniasis vaccine candidate

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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