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Scientists reveal new images of how white blood immune cells attack tumours, viral infections

Scientists from The University of Manchester have revealed new images which provide the clearest picture yet of how white blood immune cells attack viral infections and tumours.

From The University of Manchester 24 Jul 2013

FDA takes action to remove illegal diabetes products from market

The U.S. Food and Drug Administration is taking action to remove from the market illegal products, including some labeled as dietary supplements, that claim to mitigate, treat, cure or prevent diabetes and related complications.

24 Jul 2013

Digital versions of standard molecular biology tool to detect common tumor-associated mutation in CSF

Massachusetts General Hospital (MGH) researchers and their colleagues have used digital versions of a standard molecular biology tool to detect a common tumor-associated mutation in the cerebrospinal fluid (CSF) of patients with brain tumors. In their report being published in the open-access journal Molecular Therapy - Nucleic Acids, the investigators describe using advanced forms of the gene-amplification technology polymerase chain reaction (PCR) to analyze bits of RNA carried in membrane-covered sacs called extracellular vesicles for the presence of a tumor-associated mutation in a gene called IDH1.

24 Jul 2013

Discovery may help explain how anti-inflammatory steroid drugs work

A gene long presumed dead comes to life under the full moon of inflammation, Stanford University School of Medicine scientists have found.

23 Jul 2013

Novaliq receives CE mark approval for EyeSol technology

Novaliq GmbH, a drug delivery company with a focus on the topical application of ophthalmic technologies for poorly soluble drugs, today announced the successful CE mark approval for the first topical eye lubricant based on Novaliq's proprietary technology EyeSol.

23 Jul 2013

Defining '20 weeks' of pregnancy -- states and doctors don't agree

NPR reports that the way most states define what constitutes 20 weeks of pregnancy in their abortion laws isn't the same way most doctors define it. In the meantime, Mexican abortion pill sellers just across the border from Texas expect a boon after that state's new abortion restrictions.

23 Jul 2013

Study upends common perception that urban areas are more dangerous than small towns

Large cities in the U.S. are significantly safer than their rural counterparts, with the risk of injury death more than 20 percent higher in the country. A study to be published online tomorrow in Annals of Emergency Medicine upends a common perception that urban areas are more dangerous than small towns ("Safety in Numbers: Are Major Cities the Safest Places in the U.S.?").

23 Jul 2013

IT issues pose challenges for health law

News outlets also report on how other changes are affecting small business owners, hospitals and students.

23 Jul 2013

NIH awards $1.7M grant to develop effective treatments for brain disorders

Ten percent of Americans experience a seizure in their lifetime, with three million diagnosed with epilepsy, a chronic neurological disorder. Anticonvulsant medications can mitigate the hyperactivity of neurons that leads to seizures, but not without severe side effects, including cognitive impairment.

23 Jul 2013

Imprimis to begin IRB-approved Impracor Phase III trial for acute pain associated with OA of the knee

Imprimis Pharmaceuticals, Inc., which is focused on the commercialization of compounded drug formulations utilizing the FDA 505(b)(2) development pathway, today announced it has received IRB approval for its Phase III clinical trial protocol of its lead product candidate, Impracor.

23 Jul 2013

New finding provides fresh hope for women with oestrogen receptor positive breast cancer

A new finding provides fresh hope for the millions of women worldwide with oestrogen receptor positive breast cancer. Australian scientists have shown that a specific change, which occurs when tumours become resistant to anti-oestrogen therapy, might make the cancers susceptible to treatment with chemotherapy drugs.

23 Jul 2013

First Edition: July 22, 2013

Today's headlines include reports about the continuing efforts in opposition to the health law as well as a Washington Post investigation into a "flaw" in U.S. health care pricing.

22 Jul 2013

Drug release of tramadol hydrochloride increases from 1.9 to 7.5 hours by adding Novozymes Biopharma’s Hyasis®

Novozymes Biopharma, part of Novozymes A/S, a world leader in bioinnovation, today announced the release of new findings concerning the effect of Bacillus-derived Hyaluronic Acid (HA) on the drug release of tramadol hydrochloride. The new research is to be presented as a scientific poster at the 2013 Controlled Release Society (CRS) annual meeting, July 21-24, Hawaii, USA.

22 Jul 2013

Bacillus-derived Hyaluronic acid from Novozymes Biopharma, Hyasis®, increases in vitro drug release time from under 10 minutes to approximately 15 hours

An investigation undertaken by Novozymes Biopharma DK has shown that when the corticosteroid dexamethasone is formulated in a cross-linked Hyaluronic acid (HA) hydrogel, the drug’s in vitro release time increases from under 10 minutes to approximately 15 hours. In addition, the in vivo half-life of dexamethasone is shown to plateau with stable dexamethasone concentration up to four hours after injection.

22 Jul 2013

Study reveals that Hudson River polluted with antibiotic-resistant bacteria

The risk of catching some nasty germ in the Hudson River just started looking nastier. Disease-causing microbes have long been found swimming there, but now researchers have documented antibiotic-resistant strains in specific spots, from the Tappan Zee Bridge to lower Manhattan.

22 Jul 2013

African-Americans, Latinos receive less adequate mental health care than Whites

Blacks and Latinos receive less adequate mental health care than Whites, finds a new study in Health Services Research.

22 Jul 2013

Gladstone-led study finds underlying mechanisms behind Huntington's disease

Alzheimer's, Huntington's, Parkinson's. Names forever linked to what they represent: diseases that ravage the brain's neurons and leave entire regions to wither and die. These and other so-called neurodegenerative diseases are often associated with the buildup of toxic proteins that lead to the death of neurons.

22 Jul 2013

Research roundup: Eye care disparities; more complications for Medicaid patients after spine surgery; the cost to states opting against Medicaid expansion

After analyzing 2003-2004 data of patients who underwent spinal surgery at two medical institutions, they found that Medicaid beneficiaries were at much higher risk of experiencing any type of complication than patients who are privately insured. "The results of our study further support the growing body of literature that Medicaid patients have higher rates of complications," the authors write. When evaluating patients and considering the likelihood of complications, "Medicaid status should be considered as well," they concluded (Hacquebord et al., 7/15).

20 Jul 2013

Scientists to explore student-driven research model for Distributed Drug Discovery

Purdue University Indianapolis (IUPUI) will host scientists from around the world next week for the first-ever workshop devoted to Distributed Drug Discovery, an innovative, student-driven research program quickly becoming a high-impact, low-cost teaching model.

20 Jul 2013

Structural properties have changed across bacterial families without putting limits on antibiotic resistance

Antibiotic-resistant bacteria have been emerging at an alarming rate. In some of the scariest of these pathogens, the mechanism responsible for the bacteria's ability to defeat antibiotics is a complex protein molecule embedded in the bacterial cell wall -- the enzyme β-lactamase.

20 Jul 2013

Drugs News and Research

Scientists reveal new images of how white blood immune cells attack tumours, viral infections

FDA takes action to remove illegal diabetes products from market

Digital versions of standard molecular biology tool to detect common tumor-associated mutation in CSF

Discovery may help explain how anti-inflammatory steroid drugs work

Novaliq receives CE mark approval for EyeSol technology

Defining '20 weeks' of pregnancy -- states and doctors don't agree

Study upends common perception that urban areas are more dangerous than small towns

IT issues pose challenges for health law

NIH awards $1.7M grant to develop effective treatments for brain disorders

Imprimis to begin IRB-approved Impracor Phase III trial for acute pain associated with OA of the knee

New finding provides fresh hope for women with oestrogen receptor positive breast cancer

First Edition: July 22, 2013

Drug release of tramadol hydrochloride increases from 1.9 to 7.5 hours by adding Novozymes Biopharma’s Hyasis®

Bacillus-derived Hyaluronic acid from Novozymes Biopharma, Hyasis®, increases in vitro drug release time from under 10 minutes to approximately 15 hours

Study reveals that Hudson River polluted with antibiotic-resistant bacteria

African-Americans, Latinos receive less adequate mental health care than Whites

Gladstone-led study finds underlying mechanisms behind Huntington's disease

Research roundup: Eye care disparities; more complications for Medicaid patients after spine surgery; the cost to states opting against Medicaid expansion

Scientists to explore student-driven research model for Distributed Drug Discovery

Structural properties have changed across bacterial families without putting limits on antibiotic resistance

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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