Protein C News and Research

RSS

SiDMAP announces publication of Isotopolome Wide Association Study in FASEB Journal

SiDMAP, LLC, a leading provider of metabolic profiling and biomarker development services to the pharmaceutical, academic, governmental, and biotechnology industries, announced today the publication of its 13C Isotopolome Wide Association Study matrix in the official journal of the Federation of American Societies for Experimental Biology in collaboration with scientists at the University Of Utah School Of Medicine.

6 Apr 2013

Study applying OPKO Health's technology to identify synthetic peptoid in NMO patient serum published

OPKO Health, Inc. today announced the publication of a study applying its novel library screening technology to identify a synthetic peptoid that binds to anti-Aquaporin 4 antibodies in the serum of patients with Neuromyelitis optica.

6 Apr 2013

Scientists say detecting single viral protein components challenging for Ebola

By screening a library of a billion llama antibodies on live Ebola viruses in the Texas Biomedical Research Institute's highest biocontainment laboratory, scientists in San Antonio have identified a potential weakness in the make-up of these deadly agents that can immediately yield a sensitive test.

6 Apr 2013

Fruit fly study offers clues to wound healing

A person's skin and a fruit fly's exoskeleton, called a "cuticle" may not look alike, but both coverings protect against injury, infection, and dehydration.

6 Apr 2013

Study offers new possibilities for developing potent antibacterial drugs

A new study which was performed jointly at Ume- University and the University of Washington in Seattle, USA, discovered that bacteria can degrade the cell membrane of bacterial competitors with enzymes that do not harm their own membrane.

5 Apr 2013

Emergent BioSolutions provides update on TRU-016 Phase 1b study

Emergent BioSolutions Inc. today announced its decision to expand the protocol for its ongoing Phase 1b, single arm, open label study (Protocol 16009) evaluating the safety and efficacy of TRU-016 in combination with rituximab in previously untreated patients with chronic lymphocytic leukemia.

5 Apr 2013

Metallothioneins play major role in virulence of Cryptococcus neoformans

Metallothioneins, proteins able to capture metal ions, play a major role in the virulence of Cryptococcus neoformans, a fungal pathogen which causes severe infections in immunodeficient and immunocompetent individuals (AIDS patients, transplant receivers, etc.)

5 Apr 2013

Growing working blood vessels may help offer treatments for diseases that affect circulatory system

One of the major obstacles to growing new organs—replacement hearts, lungs and kidneys—is the difficulty researchers face in building blood vessels that keep the tissues alive, but new findings from the University of Michigan could help overcome this roadblock.

5 Apr 2013

Dermatology researcher secures federal grant to explore psoriasis

A dermatology researcher at Case Western Reserve University School of Medicine has secured a five-year, $1.9 million federal grant to explore whether a specific molecule may play a pivotal role in the development and progression of psoriasis.

5 Apr 2013

Wistar scientists describe mechanics of oncogene-induced senescence

Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides-the building blocks of DNA molecules-cells can suppress cancer development by forcing a damaged cell into a senescent state, where the cell remains alive yet cannot reproduce.

5 Apr 2013

Research findings provide insight into severe bacterial infectious diseases

UT Southwestern Medical Center researchers report that a pathogen annually blamed for an estimated 90 million cases of food-borne illness defeats a host's immune response by using a fat-snipping enzyme to cut off cellular communication.

5 Apr 2013

Researchers identify new set of genetic markers for Alzheimer's

Researchers at Washington University School of Medicine in St. Louis have identified a new set of genetic markers for Alzheimer's that point to a second pathway through which the disease develops.

5 Apr 2013

TSRI scientists identify new drugs for human prion disease

Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet—incurable with disturbing symptoms that include dementia, personality shifts, hallucinations and coordination problems.

4 Apr 2013

Schizophrenia patients experiencing relapse are more likely to develop UTIs

Schizophrenia patients experiencing relapse are 29 times more likely than healthy individuals to have a urinary tract infection, researchers report.

4 Apr 2013

Researchers predict probability of cardiovascular risk

Researchers at the Charité - Universitätsmedizin Berlin have managed to predict the probability of a cardiovascular patient suffering a heart attack, stroke or arterial occlusion within three months.

4 Apr 2013

Researchers identify vulnerability of lung-cancer cells that can be exploited for new therapies

Physician-researchers at UT Southwestern Medical Center have identified a vulnerability of certain lung-cancer cells - a specific genetic weakness that can be exploited for new therapies.

4 Apr 2013

Clinical trial signals new era in treatment of neurodegererative disorders

The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis - blocking production of a mutant protein that causes an inherited form of the progressive neurodegererative disease - may be a first step towards a new era in the treatment of such disorders.

4 Apr 2013

Researchers discover injectable protein to reverse symptoms of dangerous conditions

The creation of new blood vessels in the body, called "angiogenesis," is usually discussed in connection with healing wounds and tumors. But it's also an ongoing process in the female reproductive tract, where the growth and breaking of blood vessels is a normal part of the menstrual cycle. But abnormal growth of blood vessels can have painful consequences and resultant pathologies.

4 Apr 2013

Glowing bacteria inside squids use light and chemical signals to control circadian rhythms

Glowing bacteria inside squids use light and chemical signals to control circadian-like rhythms in the animals, according to a study to be published on April 2 in mBio-, the online open-access journal of the American Society for Microbiology.

4 Apr 2013

Polymer scaffolds can advance the development of cancer therapeutics

Porous polymer scaffolds fabricated to support the growth of biological tissue for implantation may hold the potential to greatly accelerate the development of cancer therapeutics.

3 Apr 2013