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Scientists identify potential treatment for idiopathic pulmonary fibrosis

Investigators at the University of Alabama at Birmingham (UAB) have unlocked another piece of the puzzle surrounding idiopathic pulmonary fibrosis, an often fatal lung disease with no cure and no effective treatments.

25 Mar 2013

Researchers study gene variants that bear signature for inflammatory disease susceptibility

In new research published in the April 4, 2013 issue of The American Journal of Human Genetics, researchers from Brigham and Women's Hospital demonstrate that some variants in our genes that could put a person at risk for inflammatory diseases such as multiple sclerosis, Crohn's disease or rheumatoid arthritis, have been the target of natural selection over the course of human history.

25 Mar 2013

Researchers expand hematopoietic stem cells for bone marrow transplantation

More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.

25 Mar 2013

Protein with key job in muscle function moonlights in nucleus to help regulate genes

A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.

25 Mar 2013

Study reveals role of SNX27 protein in brain function

What is it about the extra chromosome inherited in Down syndrome-chromosome 21-that alters brain and body development? Researchers at Sanford-Burnham Medical Research Institute have new evidence that points to a protein called sorting nexin 27, or SNX27.

25 Mar 2013

LMU researchers identify microRNA that offers promising target for new therapies

Atherosclerosis, an inflammatory reaction, is at the root of the most common forms of cardiovascular disease. Researchers at Ludwig-Maximilians-Universitaet in Munich have now identified a microRNA that plays a prominent role in the process, and offers a promising target for new therapies.

25 Mar 2013

Researchers study how nerve cells repair themselves after injury

One molecule makes nerve cells grow longer. Another one makes them grow branches. These new experimental manipulations have taken researchers a step closer to understanding how nerve cells are repaired at their farthest reaches after injury.

25 Mar 2013

International support rising for adopting universal water security

Amid changing weather and water patterns worldwide and forecasts of more severe transformations to come, calls have been growing for the UN Security Council to include water issues on its agenda.

25 Mar 2013

Experts say age, ethnicity and genetics play a critical role in the development of prostate cancer

Genetics, age and ethnicity are risk factors for prostate cancer, while the evidence for obesity, smoking and diabetes as associated risks remains uncertain, according to prostate cancer experts.

24 Mar 2013

Fralin Life Science Institute researchers use TALENS to alter mosquito genome

Virginia Tech researchers successfully used a gene disruption technique to change the eye color of a mosquito - a critical step toward new genetic strategies aimed at disrupting the transmission of diseases such as dengue fever.

22 Mar 2013

Researchers develop new approach for HIV vaccine development

Decades of research and three large-scale clinical trials have so far failed to yield an effective HIV vaccine, in large part because the virus evolves so rapidly that it can evade any vaccine-induced immune response.

22 Mar 2013

MU researchers redefine key regulatory process in defective protein responsible for cystic fibrosis

A little more than a year after the FDA approved Kalydeco (Vx-770), the first drug of its kind to treat the underlying cause of cystic fibrosis, University of Missouri researchers believe they have found exactly how this drug works and how to improve its effectiveness in the future.

22 Mar 2013

Soybeans can prevent cancer

Soybean meal is a bi-product following oil extraction from soybean seeds. It is rich in protein, which usually makes up around 40% of the nutritional components of the seeds and dependent on the line, and can also contain high oleic acid (a monounsaturated omega-9 fatty acid).

21 Mar 2013

Disinfectant mouthwashes may be effective against cancers of the mouth and throat

Patients who suffer from gingivitis are often advised to use disinfectant mouthwashes. In the future, the active ingredients in these products could be used in a completely different area: As scientists have reported in the journal Angewandte Chemie, Chlorhexidin and Alexidin increase programmed cell death and may be effective against cancers of the mouth and throat.

21 Mar 2013

WUSTL's Wang receives NSF grant to study oxygen consumption rates of individual cells

When scientists study cells, they need to know how much oxygen each cell consumes to determine its metabolism. However, existing technology limits this study to groups of cells, not individual cells. Lihong Wang, PhD, plans to change that.

21 Mar 2013

CPF and PFF to partner with ATS to fund pulmonary fibrosis research

The Coalition for Pulmonary Fibrosis, the Pulmonary Fibrosis Foundation, and the American Thoracic Society-the world's leading professional organization for pulmonary, critical care and sleep medicine-today announced that the CPF and the PFF will again partner with the ATS to fund pulmonary fibrosis research.

21 Mar 2013

Novel modification of structural protein implicated

Studying a protein that gives structure to the nucleus of cells, Johns Hopkins researchers stumbled upon mutations associated with familial partial lipodystrophy, a rare disease that disrupts normal patterns of fat distribution throughout the body.

21 Mar 2013

Researchers develop promising drug candidate to treat psoriasis

Ben-Gurion University of the Negev researchers, in collaboration with Teva Pharmaceutical Industries Ltd., have developed a promising drug candidate to treat psoriasis.

21 Mar 2013

APS to present scientific abstracts at Experimental Biology 2013

The American Physiological Society is one of six scientific societies sponsoring the meeting Experimental Biology 2013, being held April 20-24, 2013 at the Boston Convention and Exhibition Center, in Boston, Mass.

21 Mar 2013

Combination of HUCBCs and Simvastatin offers promising therapy for stroke: Study

Researchers at the Henry Ford Health System (Detroit, MI) and colleagues at Saneron CCEL Therapeutics, Inc. of Tampa, Florida, have found that when human umbilical cord blood cells were transplanted into test rats modeled with stroke, the addition of Simvastatin to the HUCBCs significantly increased the therapeutic benefit of the HUCBCs.

21 Mar 2013

Protein C News and Research

Scientists identify potential treatment for idiopathic pulmonary fibrosis

Researchers study gene variants that bear signature for inflammatory disease susceptibility

Researchers expand hematopoietic stem cells for bone marrow transplantation

Protein with key job in muscle function moonlights in nucleus to help regulate genes

Study reveals role of SNX27 protein in brain function

LMU researchers identify microRNA that offers promising target for new therapies

Researchers study how nerve cells repair themselves after injury

International support rising for adopting universal water security

Experts say age, ethnicity and genetics play a critical role in the development of prostate cancer

Fralin Life Science Institute researchers use TALENS to alter mosquito genome

Researchers develop new approach for HIV vaccine development

MU researchers redefine key regulatory process in defective protein responsible for cystic fibrosis

Soybeans can prevent cancer

Disinfectant mouthwashes may be effective against cancers of the mouth and throat

WUSTL's Wang receives NSF grant to study oxygen consumption rates of individual cells

CPF and PFF to partner with ATS to fund pulmonary fibrosis research

Novel modification of structural protein implicated

Researchers develop promising drug candidate to treat psoriasis

APS to present scientific abstracts at Experimental Biology 2013

Combination of HUCBCs and Simvastatin offers promising therapy for stroke: Study

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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