Protein C News and Research

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Cytomegalovirus employs a novel trick to hide from immune detection

A virus that most people have probably never heard of, yet most of us carry, is the number 1 infectious cause of congenital birth defects. One in 750 children are born with, or develop, permanent disabilities such as hearing loss or brain damage as a result of CMV (cytomegalovirus) infection in the womb.

17 Mar 2013

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies.

16 Mar 2013

Researchers identifiy elusive anti-cancer property of vitamin E

Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find. Many animal studies have suggested that vitamin E could prevent cancer, but human clinical trials following up on those findings have not shown the same benefits.

16 Mar 2013

Discovery could lead to new target for treatment of cocaine addiction

Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug.

16 Mar 2013

Study: Flagellin plays a critical role in regulating host innate defences against UTIs

A new study by British scientists reveals that motile Escherichia coli isolates demonstrated significant activation of NF-κB signaling suggesting that flagellin plays a key role in up-regulating the host innate defences against urinary tract infections (UTIs).

15 Mar 2013

Luminex collaborates with Merck to design companion diagnostic device for Alzheimer’s disease

WHITEHOUSE STATION known as MSD outside the United States and Canada, and Luminex Corporation have signed a collaboration and license agreement to develop a companion diagnostic device that will be evaluated to help screen patients for recruitment into Merck's clinical development program for MK-8931, a novel oral beta amyloid precursor protein site cleaving enzyme (BACE) inhibitor and Merck's lead investigational candidate for Alzheimer's disease (AD).

From Luminex 15 Mar 2013

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific for proteins on the outside of the virus, specifically the hemagglutinin protein.

15 Mar 2013

Brown fat cells protective against obesity and diabetes

Brown fat is a hot topic, pardon the pun. Brown fats cells, as opposed to white fat cells, make heat for the body, and are thought to have evolved to help mammals cope with the cold. But, their role in generating warmth might also be applied to coping with obesity and diabetes.

15 Mar 2013

Fast-progressing hearing impairment linked to fatal Creutzfeldt-Jakob Disease

Rapid hearing loss in both ears may be a symptom of the rare but always-fatal Creutzfeldt-Jakob Disease and should be considered a reason for clinicians to test for the disorder.

15 Mar 2013

Researchers identify enzymes that activate coronavirus for infection

Scientists all over the world are on a quest for an antidote since the first patient died from the new coronavirus in summer 2012. Infection Researchers from the German Primate Center have now identified enzymes that activate the virus for infection.

15 Mar 2013

Probiotics help stress-associated gastrointestinal disorders, study says

For those with irritable bowel syndrome who wonder if stress aggravates their intestinal disorder, a new University of Michigan Health System study shows it's not all in their head.

15 Mar 2013

Max Planck Florida Institute for Neuroscience gets grant for research into neurological disorders

The Max Planck Florida Institute for Neuroscience, the first and only U.S. extension of the prestigious Max Planck Society, today announced it has received approximately $1,257,500 in grant funding from prestigious national and international organizations to fund research into Parkinson-s, epilepsy and other neurological disorders.

15 Mar 2013

Study identifies genetic cause of developmental delay in Amish individuals in USA

Researchers from the research group in growth factors and cell differentiation at the University of Barcelona (UB) and the IDIBELL and have participated in an international study that has identified the genetic cause of developmental delay observed in Amish individuals in the USA.

15 Mar 2013

Researchers develop single molecule test for detecting methylated DNA

Collaborators from Mayo-Illinois Alliance for Technology Based Healthcare have developed a new, single molecule test for detecting methylated DNA. Methylation -- the addition of a methyl group of molecules to a DNA strand -- is one of the ways gene expression is regulated.

15 Mar 2013

Research shows THz pulses destroy skin tissue and increase tumor-suppressing proteins

Terahertz (THz) radiation, a slice of the electromagnetic spectrum that occupies the middle ground between microwaves and infrared light, is rapidly finding important uses in medical diagnostics, security, and scientific research. As scientists and engineers find evermore practical uses for this form of radiation, questions persist about its potential human health risks.

15 Mar 2013

VCP gene mutations cause neurological conditions including IBMPFD and ALS

New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone and Frontotemporal Dementia (IBMPFD), and the motor neuron disease Amyotrophic Lateral Sclerosis (ALS).

14 Mar 2013

IU researchers awarded $3.2 million grant to develop new treatments for pancreatic cancer

Two Indiana University researchers have been awarded a multi-year, $3.2 million grant to develop and improve therapies for pancreatic cancer, the fourth leading cause of cancer death in the United States.

14 Mar 2013

Scientists to create new human monoclonal antibody targeting protein associated with cancer

Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer are buried inside cancer cells.

14 Mar 2013

Iron imbalance caused by prion proteins leads to cell death in CJD, researchers find

An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found.

14 Mar 2013

Research finding aids efforts toward cytomegalovirus vaccine

A virus most people probably have never heard of, but that the majority of us carry, is the No. 1 infectious cause of congenital birth defects in the U.S. today. Because of cytomegalovirus (CMV) infection during in utero development, 1 in 750 children are born with or develop permanent disabilities such as hearing loss or brain damage.

14 Mar 2013

Protein C News and Research

Cytomegalovirus employs a novel trick to hide from immune detection

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Researchers identifiy elusive anti-cancer property of vitamin E

Discovery could lead to new target for treatment of cocaine addiction

Study: Flagellin plays a critical role in regulating host innate defences against UTIs

Luminex collaborates with Merck to design companion diagnostic device for Alzheimer’s disease

Study: Novel strategy could lead to universal influenza vaccine that can provide long-lasting protection

Brown fat cells protective against obesity and diabetes

Fast-progressing hearing impairment linked to fatal Creutzfeldt-Jakob Disease

Researchers identify enzymes that activate coronavirus for infection

Probiotics help stress-associated gastrointestinal disorders, study says

Max Planck Florida Institute for Neuroscience gets grant for research into neurological disorders

Study identifies genetic cause of developmental delay in Amish individuals in USA

Researchers develop single molecule test for detecting methylated DNA

Research shows THz pulses destroy skin tissue and increase tumor-suppressing proteins

VCP gene mutations cause neurological conditions including IBMPFD and ALS

IU researchers awarded $3.2 million grant to develop new treatments for pancreatic cancer

Scientists to create new human monoclonal antibody targeting protein associated with cancer

Iron imbalance caused by prion proteins leads to cell death in CJD, researchers find

Research finding aids efforts toward cytomegalovirus vaccine

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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