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Nose drops of modified 'friendly' bacteria offer protection against meningitis

A world-first trial has shown that nose drops of modified 'friendly' bacteria protect against meningitis.

12 Jul 2021

Composition and structure of nasopharyngeal microbiome relate to COVID-19 disease severity

Breathing treatments are provided to hospitalized COVID-19 patients. In this study, the researchers examined the community composition in relation to three attributes - COVID-19 status, breathing assistance, and antibiotic use. This study is published in the journal, Applied Microbiology.

12 Jul 2021

Novel cold-tolerant bacterium produces a red bio-pigment with germ-killing properties

A team of researchers from Shoolini University, Himachal Pradesh, India have discovered a psychrophilic bacterial strain, called Rhodonellum psychrophilum GL8, at the high altitude Pangong Tso Lake in the Himalayas.

12 Jul 2021

Immaturity of gut microbiota and epithelial barriers linked to neonatal meningitis

Meningitis is associated with high mortality and frequently causes severe sequelae. Newborn infants are particularly susceptible to this type of infection; they develop meningitis 30 times more often than the general population.

9 Jul 2021

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

Certain metabolites of bacteria from the intestine make immune cells more aggressive as a new study conducted by scientists from Würzburg and Marburg reveals. The findings could help improve cancer therapies.

9 Jul 2021

How do host factors like the lung microbiome aid in SARS‐CoV‐2 infection?

A new article has been published in Cellular and Molecular Lifesciences, which focuses on the connection between host factors and the worsening of the COVID-19. Further, the impact of the virus on the host’s microbiome and secondary infection has also been studied.

8 Jul 2021

Using commensal bacteria to produce vaccine-like immune responses to dangerous bacterium

Researchers have produced vaccine-like immune responses to a dangerous bacterium by colonizing 26 healthy volunteers with a related, but harmless, commensal bacterial species. The first-in-human, controlled infection study showed the strategy was safe, as no side effects were reported and the volunteers didn't transmit the commensal bacteria to bedroom-sharers over the 90-day study.

8 Jul 2021

Enzyme inhibitor boosts immune system to fight MRSA and other dangerous skin infections

In what turned out to be one of the most important accidents of all time, Scottish bacteriologist Alexander Fleming returned to his laboratory after a vacation in 1928 to find a clear zone surrounding a piece of mold that had infiltrated a petri dish full of Staphylococcus aureus (S. aureus), a common skin bacterium he was growing.

8 Jul 2021

Using AI to find new pharmaceutical applications for natural products

Artificial intelligence (AI) is able to recognize the biological activity of natural products in a targeted manner, as researchers at ETH Zurich have demonstrated.

7 Jul 2021

Mother-to-baby SARS-CoV-2 transmission in pregnancy possible but rare, says study

A new meta-analysis, released on the medRxiv* preprint server, suggests that, though possible, the virus is rarely transmitted to the newborn in real life. A scientific brief from the World Health Organization (WHO) in February 2021 describes three mechanisms by which the virus might be transmitted from the mother to the fetus or newborn.

7 Jul 2021

New drug can significantly reduce flashbacks and nightmares in PTSD patients

Post-traumatic stress disorder (PTSD) rings a bell for many, due to its rampant references in pop culture, and more, importantly, its prevalence in today's society. It is only probable that this disorder, which develops after shocking or dangerous events, would unfortunately affect the lives of many people.

7 Jul 2021

Fecal transplant and fiber supplementation can benefit patients with obesity-related metabolic syndrome

A transplant of healthy gut microbes followed by fiber supplements benefits patients with severe obesity and metabolic syndrome, according to University of Alberta clinical trial findings published today in Nature Medicine.

6 Jul 2021

Simple blood tests may help prevent inaccuracy in the diagnosis of severe malaria

Using simple blood tests could help researchers identify children who have been misidentified as having severe malaria, according to a study published today in eLife.

6 Jul 2021

Antibiotic clofoctol shows potential against SARS-CoV-2

In a recent study, a group of French researchers aimed to reduce the regulatory preclinical development steps that potential candidates are normally subjected to.

5 Jul 2021

Stool transplant may be worth exploring as treatment option for COVID-19

It might be worth exploring stool transplant to treat COVID-19 infection, suggest doctors in a letter published online in the journal Gut, after they used the procedure in two patients to prevent the recurrence of another bacterial infection.

2 Jul 2021

Hi-tech lab taps advanced technology to boost Singapore's future pandemic response

Nanyang Technological University, Singapore (NTU Singapore) and Pathnova Laboratories, a medical diagnostic company backed by Temasek Life Sciences Accelerator and headquartered in Temasek Life Sciences Laboratory, is contributing to Singapore's COVID-19 diagnostic capability through its partnership in a new clinical diagnostic laboratory.

2 Jul 2021

Study explores lectins from plants, fungi, algae and cyanobacteria as pan-coronavirus inhibitors

In a recently published article scientists have provided a detailed description of the utility of mannose-specific lectins in preventing coronavirus infections. They have specifically explained how mannose-specific lectins derived from plants, algae, fungi, and bacteria selectively bind N-glycans present on the surface of viral spike protein and how such interactions can be medically utilized to control coronavirus transmission.

1 Jul 2021

New study maps evolutionary history and interrelationships of protein domains

Proteins have been quietly taking over our lives since the COVID-19 pandemic began. We've been living at the whim of the virus's so-called "spike" protein, which has mutated dozens of times to create increasingly deadly variants. But the truth is, we have always been ruled by proteins. At the cellular level, they're responsible for pretty much everything.

1 Jul 2021

Intranasal COVID-19 vaccine developed from bacterial extracellular vesicle induces robust antibody response in preclinical trials

A team of US-based scientists recently developed a novel vaccine candidate against SARS-CoV-2, the causative pathogen of COVID-19. The vaccine is composed of extracellular vesicles of Salmonella typhimurium incorporated with the spike receptor-binding domain (RBD) of SARS-CoV-2. Upon intranasal administration in hamsters, the vaccine induces strong blood antibody titers and protects against severe COVID-19.

30 Jun 2021

COVID-19 prevalence among hospitalized infants may depend on levels of community transmission

How common COVID-19 is among infants may depend on the degree of the pandemic virus circulating in a community, a new study finds.

30 Jun 2021

Bacterial News and Research

Nose drops of modified 'friendly' bacteria offer protection against meningitis

Composition and structure of nasopharyngeal microbiome relate to COVID-19 disease severity

Novel cold-tolerant bacterium produces a red bio-pigment with germ-killing properties

Immaturity of gut microbiota and epithelial barriers linked to neonatal meningitis

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

How do host factors like the lung microbiome aid in SARS‐CoV‐2 infection?

Using commensal bacteria to produce vaccine-like immune responses to dangerous bacterium

Enzyme inhibitor boosts immune system to fight MRSA and other dangerous skin infections

Using AI to find new pharmaceutical applications for natural products

Mother-to-baby SARS-CoV-2 transmission in pregnancy possible but rare, says study

New drug can significantly reduce flashbacks and nightmares in PTSD patients

Fecal transplant and fiber supplementation can benefit patients with obesity-related metabolic syndrome

Simple blood tests may help prevent inaccuracy in the diagnosis of severe malaria

Antibiotic clofoctol shows potential against SARS-CoV-2

Stool transplant may be worth exploring as treatment option for COVID-19

Hi-tech lab taps advanced technology to boost Singapore's future pandemic response

Study explores lectins from plants, fungi, algae and cyanobacteria as pan-coronavirus inhibitors

New study maps evolutionary history and interrelationships of protein domains

Intranasal COVID-19 vaccine developed from bacterial extracellular vesicle induces robust antibody response in preclinical trials

COVID-19 prevalence among hospitalized infants may depend on levels of community transmission

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