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Researchers develop synthetic cardiac stem cells that offer therapeutic benefits

Researchers from North Carolina State University, the University of North Carolina at Chapel Hill and First Affiliated Hospital of Zhengzhou University have developed a synthetic version of a cardiac stem cell.

26 Dec 2016

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment.

22 Dec 2016

New research offers valuable insight for developing more effective drugs to treat IBD

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis.

22 Dec 2016

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

A new Tel Aviv University study finds that a popular food supplement called phosphatidylserine may be instrumental in reversing the detrimental effects of Familial Dysautonomia (FD), a debilitating neurodegenerative disorder that affects approximately 1 in 31 Jewish people of Eastern European, or Ashkenazi, ancestry.

21 Dec 2016

New graphene system can detect activity levels of interfaced normal and cancer cells

What can't graphene do? You can scratch "detect cancer" off of that list. By interfacing brain cells onto graphene, researchers at the University of Illinois at Chicago have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, noninvasive tool for early cancer diagnosis.

20 Dec 2016

Combination therapy holds great promise to clear precancerous skin lesions

A combination of two FDA-approved drugs - a topical chemotherapy and an immune-system-activating compound - was able to rapidly clear actinic keratosis lesions from patients participating in a clinical trial.

19 Dec 2016

Scientists discover mechanism that hijacks immune system's response to tuberculosis

Scientists have discovered the mechanism that hijacks the immune system's response to tuberculosis, revealing an important new drug target for the disease that kills more than 1 million people each year.

17 Dec 2016

Retinoblastoma protein plays larger role in tumor suppression, study finds

The Retinoblastoma protein (pRB) has long been studied for its role in cell growth and the prevention of cancer.

16 Dec 2016

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

16 Dec 2016

Good-tasting food does not lead to weight gain, new research suggests

Does eating good-tasting food make you gain weight? Despite the common perception that good-tasting food is unhealthy and causes obesity, new research from the Monell Center using a mouse model suggests that desirable taste in and of itself does not lead to weight gain.

16 Dec 2016

URMC researchers identify potential new means of treating severe genetic diseases in children

University of Rochester Medical Center researchers believe they have identified a potential new means of treating some of the most severe genetic diseases of childhood, according to a study in PLOS Biology.

16 Dec 2016

Researchers correct motor symptoms linked to Parkinson's disease in mice

A research group led by University of Helsinki Docent Timo Myöhänen has succeeded in correcting the motor symptoms associated with Parkinson's disease in mice.

15 Dec 2016

Viral infection during pregnancy affects maternal care and can trigger depression in offspring

A viral infection in a pregnant woman not only affects her subsequent ability to provide maternal care but can also trigger depression in her offspring, which can then even extend into the next generation as a result of changes to genetic mechanisms in the brain.

15 Dec 2016

Mouse Model News and Research

Researchers develop synthetic cardiac stem cells that offer therapeutic benefits

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

New research offers valuable insight for developing more effective drugs to treat IBD

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

New graphene system can detect activity levels of interfaced normal and cancer cells

Combination therapy holds great promise to clear precancerous skin lesions

Scientists discover mechanism that hijacks immune system's response to tuberculosis

Retinoblastoma protein plays larger role in tumor suppression, study finds

Researchers identify attractive drug candidate to target glioma tumors

Good-tasting food does not lead to weight gain, new research suggests

URMC researchers identify potential new means of treating severe genetic diseases in children

Researchers correct motor symptoms linked to Parkinson's disease in mice

Viral infection during pregnancy affects maternal care and can trigger depression in offspring

NIH scientists create Salmonella-infected mouse model to study life-threatening meningitis

Researchers create 2-for-1 vaccine that protects mice from MERS and rabies

Researchers show how microRNAs play key role in tumor progression and response to radiation

New mouse model provides key information for understanding cortical circuit development

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

Scientists identify microrna that provides clues for quieting auditory hallucinations of schizophrenia

New self-regulating smart patch releases blood-thinning drugs when necessary

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