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Three papers reveal structure and workings of G protein-coupled receptors

Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented detail the structure and workings of G protein-coupled receptors (GPCRs), a large family of human proteins that are the target of one-third to one-half of modern drugs.

29 Sep 2011

ACRO releases statement on World Heart Day

The Association of Clinical Research Organizations (ACRO), which represents the global leaders in clinical outsourcing, today released the following statement in recognition of World Heart Day.

29 Sep 2011

Genetic variant may increase severity of coronary artery disease in patients with diabetes

Researchers at Washington University School of Medicine in St. Louis have identified the first genetic variant associated with severity of coronary artery disease in patients with type 2 diabetes.

29 Sep 2011

HHS awards prevention funds with Community Transformation Grants

News outlets report on local winners, how they will use these new resources to promote healthy living and disease prevention and how the funding is sometimes at odds with their leaders' opposition to the health law.

29 Sep 2011

Study reports positive effect of RESPeRATE on CHF patients

InterCure Ltd., a medical device company publicly traded on the Tel-Aviv Stock Exchange, today announced that European Journal of Heart Failure, a peer reviewed medical journal of the European Society of Cardiology, published the results of a 72-patients, randomized, controlled study which demonstrated that device-guided respiratory modulation with RESPeRATE applied at the home setting can significantly relieve symptoms of heart failure in elderly patients.

29 Sep 2011

People with prehypertension have higher risk of experiencing future stroke

People with prehypertension have a 55 percent higher risk of experiencing a future stroke than people without prehypertension, report researchers at the University of California, San Diego School of Medicine in a new meta-analysis of scientific literature published in the September 28 online issue of the journal Neurology.

29 Sep 2011

Cincinnati Children's to conduct first pediatric migraine medicine clinical trial

Cincinnati Children's Hospital Medical Center has received a $12 million grant from the National Institutes of Health to conduct the first clinical trial to determine the medication of choice for preventing migraines in children and teens.

29 Sep 2011

Congress must not make cuts to crucial government-funded aging research

America's experts on aging are headed for meetings with their senators and representatives to underscore the needs of the country's senior population, spurred by the first-ever Take Action Week organized by The Gerontological Society of America - the nation's largest interdisciplinary organization devoted to the field of aging.

28 Sep 2011

Top medical research organisations call EU for urgent clinical trial reforms

Top medical research organisations are calling on the European Union for urgent reforms to the way clinical trials are regulated across the continent.

28 Sep 2011

Viewpoints: Lots of advice for super committee on Medicare, Medicaid

Obama partisans, you must consider at least two, possibly mixed results - a politically risky legal battle on the individual mandate in the middle of a presidential campaign, and added insurance that Obama administration lawyers will see the case through its final appeal.

28 Sep 2011

Some stroke patients may benefit from treatment outside the typical 3 hour window

Stroke victims may have a longer window of opportunity to receive treatment to save their brain cells, demonstrates a literature review published by University of Alberta medical researchers in Lancet Neurology.

28 Sep 2011

Aggressive glycemic control does not improve clinical outcomes for diabetic CABG patients

Surgeons from Boston Medical Center (BMC) have found that in diabetic patients undergoing coronary artery bypass graft (CABG) surgery, aggressive glycemic control does not result in any significant improvement of clinical outcomes as compared with moderate control.

28 Sep 2011

Dialog Devices receives CE mark and ISO certification for Padd

A ground-breaking device which "sees" beneath the skin to spot circulation problems has passed an important milestone on its journey to commercialisation.

28 Sep 2011

UCSF neuroscientist wins PECASE award for research into addiction

Linda Wilbrecht, PhD, a neuroscientist at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco (UCSF), is one of 94 researchers named today by President Obama as a recipient of the Presidential Early Career Awards for Scientists and Engineers (PECASE).

28 Sep 2011

Engager Transcatheter Aortic Valve Implantation System pivotal trial to be conducted at 11 European centers

Medtronic, Inc. today announced the start of the Engager European Pivotal Trial to pursue CE Mark for the Engager Transcatheter Aortic Valve Implantation System in patients suffering from severe aortic stenosis.

From Medtronic 28 Sep 2011

More predictability in the chaos of infectious Chagas disease transmission

Despite what Hollywood would have you believe, not all epidemics involve people suffering from zombie-like symptoms--some can only be uncovered through door-to-door epidemiology and advanced mathematics.

28 Sep 2011

A Daddy’s heart is healthier: Study

A new study shows that fathers are less likely to die of heart disease than men who’ve never had kids. This raises questions about a possible biological link between male infertility and overall health. Other recent studies have found a connection between testicular and prostate cancer and infertility.

27 Sep 2011

WPI professor receives AHA fellowship for research into cardiovascular disease

Dalin Tang, professor of mathematical sciences and biomedical engineering at Worcester Polytechnic Institute (WPI), has been elected a fellow of the American Heart Association (AHA). Tang was elected to fellowship by the AHA's Council on Basic Cardiovascular Sciences in recognition of his "major and productive contributions in cardiovascular basic science."

27 Sep 2011

HCRI completes enrollment in dual antiplatelet therapy clinical trial

The Harvard Clinical Research Institute (HCRI) announced today that the enrollment phase of the DAPT Study has been successfully completed. The DAPT Study is a four-year clinical trial investigating the duration of dual antiplatelet therapy (DAPT, the combination of aspirin and a thienopyridine/antiplatelet medication to reduce the risk of blood clots) following drug-eluting stent implantations.

27 Sep 2011

Insurers, patients wrestle with payment, care issues and strategies

News outlets report on a variety of issues reflecting the insurance hassles patients sometimes face and the efforts by insurance companies to find profits in better-coordinated care.

27 Sep 2011