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Vical announces issuance of U.S. Patent for cytomegalovirus vaccines

Vical Incorporated announced today the issuance of U.S. Patent No. 7,888,112 covering DNA vaccines for cytomegalovirus containing specific gene sequences and formulated with Vical's Vaxfectin adjuvant.

16 Feb 2011

Mutations in gene linked to structure of the heart seen in Ebstein's anomaly patients

Ebstein's anomaly is a rare congenital valvular heart disease. Now, in patients with this disease, researchers of the Academic Medical Center Amsterdam in the Netherlands, the University of Newcastle, UK and the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have identified mutations in a gene which plays an important role in the structure of the heart.

16 Feb 2011

Break-induced Replication more likely to cause genetic mutation than normal cell repair

Researchers from Indiana University-Purdue University Indianapolis and Umea- University report in a study published in the February 15, 2011, issue of PLoS Biology that a method by which cells repair breaks in their DNA, known as Break-induced Replication, is up to 2,800 times more likely to cause genetic mutation than normal cell repair.

16 Feb 2011

Researchers develop new DNA test for accurate detection of Turner syndrome in children

As a child grows, a short stature is not usually cause for concern, but it is often the only sign of a condition called Turner syndrome. Prevalent in girls, Turner syndrome is a genetic defect that short-circuits normal growth and leads to cardiac and renal problems. It is not commonly detected until age 10 or older when a youngster's unusually short height raises suspicions.

16 Feb 2011

Flu vaccine update

This new vaccine which could become available in the United States in the next few years, is made by growing the influenza virus in cultures of animal cells rather than in the chicken eggs that have been used for more than five decades. This shortens the process by six months. Using animal cells, which are grown in enclosed steel tanks, also reduces the risk of bacterial contamination, which has led to shortages of seasonal vaccines in some years. The study was reported in The Lancet this Tuesday.

16 Feb 2011

The Children's Hospital of Philadelphia establishes Jeffrey Modell Endowed Chair in Pediatric Immunology Research

The Children's Hospital of Philadelphia today announced the establishment of the Jeffrey Modell Endowed Chair in Pediatric Immunology Research.

16 Feb 2011

WaferGen offers SNP Genotyping screening with new SmartChip PCR System

WaferGen Biosystems, Inc. a leading developer of state-of-the-art genomic analysis systems, today announced that it is offering an early access program for high-throughput Single Nucleotide Polymorphism Genotyping through its new SmartChip Real-Time PCR System.

16 Feb 2011

American Academy of Dermatology releases final guidelines of care for psoriasis

Building on the evidence-based findings of five previously published guidelines of care that examine the use of a variety of medical therapies for the management and treatment of psoriasis and psoriatic arthritis, the American Academy of Dermatology has released its sixth and final guidelines of care for psoriasis.

16 Feb 2011

Research: Whole genome sequencing on tumors can treat pancreatic cancer

Whole genome sequencing - spelling out a person's entire DNA genetic code - has moved one step closer to being a medical option for direct patient care.

16 Feb 2011

AMT 2010 total net income increases to EUR 1.4 million

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, today reported its results for the year to December 31, 2010.

16 Feb 2011

Genetic proof for anti-cancer properties of antioxidants and autophagy inhibitors

Researchers from Jefferson's Kimmel Cancer Center have genetic evidence suggesting the antioxidant drugs currently used to treat lung disease, malaria and even the common cold can also help prevent and treat cancers because they fight against mitochondrial oxidative stress-a culprit in driving tumor growth.

16 Feb 2011

Partners, Luminex team up to discover novel biomarkers, develop clinical assays

Luminex Corporation announced today that it has teamed with Partners HealthCare toward the discovery of novel biomarkers and development of clinical assays.

From Luminex 16 Feb 2011

Researchers use computers to capture chemical signal structure that triggers metastatic cancer

In cancer and other pathological diseases, researchers are discovering that packaging is important: specifically, how DNA - about two meters long when unwound and stretched - coils up and compacts neatly inside the nucleus of a cell.

15 Feb 2011

Study: Active wound healing can lead to increased risk of basal cell carcinoma in skin

Processes that are involved in active wound healing can lead to an increased risk for basal cell carcinoma in the skin. This is the conclusion of a recent study from the Swedish medical university Karolinska Institutet, published in the journal PNAS.

15 Feb 2011

Scholars urge scientific community to act against negative effects of patenting in stem cell field

In an opinion piece published Feb. 10 in the journal Science, a team of scholars led by a Johns Hopkins bioethicist urges the scientific community to act collectively to stem the negative effects of the patenting and privatizing of stem cell lines, data and pioneering technologies. This means grappling with the ambiguity of several fundamental distinctions typically made in ethics, law and common practice, the experts insist.

15 Feb 2011

How human brain wires itself into complex networks

Neurobiologists at UC San Diego have discovered new ways by which nerves are guided to grow in highly directed ways to wire the brain during embryonic development.

15 Feb 2011

Screening breast MRIs can detect invasive cancers in women with history of chest irradiation

Breast cancer screening with MRI can detect invasive cancers missed on mammography in women who've undergone chest irradiation for other diseases, according to a new study published online and in the April print edition of Radiology.

15 Feb 2011

Researchers find placentas of preeclampsic women have abundance of genes linked with immune system regulation

Researchers at North Carolina State University have discovered that the placentas of women who suffer preeclampsia during pregnancy have an overabundance of a gene associated with the regulation of the body's immune system. Their discovery may lead to improved screening and prenatal care for these patients and their babies.

14 Feb 2011

NHGRI's new strategic plan to identify genetic bases of most single-gene disorders

A new strategic plan from an arm of the National Institutes of Health envisions scientists being able to identify genetic bases of most single-gene disorders and gaining new insights into multi-gene disorders in the next decade. This should lead to more accurate diagnoses, new drug targets and the development of practical treatments for many who today lack therapeutic options, according to the plan from the National Human Genome Research Institute (NHGRI).

14 Feb 2011

New study establishes link between coronary artery disease and genetic susceptibility

A new study involving researchers at the Scripps Translational Science Institute and Scripps Health patients reveals major scientific progress in understanding the mechanism of heart disease at the molecular and genomic levels. STSI is an initiative of Scripps Health in collaboration with The Scripps Research Institute.

14 Feb 2011

Genetic News and Research

Vical announces issuance of U.S. Patent for cytomegalovirus vaccines

Mutations in gene linked to structure of the heart seen in Ebstein's anomaly patients

Break-induced Replication more likely to cause genetic mutation than normal cell repair

Researchers develop new DNA test for accurate detection of Turner syndrome in children

Flu vaccine update

The Children's Hospital of Philadelphia establishes Jeffrey Modell Endowed Chair in Pediatric Immunology Research

WaferGen offers SNP Genotyping screening with new SmartChip PCR System

American Academy of Dermatology releases final guidelines of care for psoriasis

Research: Whole genome sequencing on tumors can treat pancreatic cancer

AMT 2010 total net income increases to EUR 1.4 million

Genetic proof for anti-cancer properties of antioxidants and autophagy inhibitors

Partners, Luminex team up to discover novel biomarkers, develop clinical assays

Researchers use computers to capture chemical signal structure that triggers metastatic cancer

Study: Active wound healing can lead to increased risk of basal cell carcinoma in skin

Scholars urge scientific community to act against negative effects of patenting in stem cell field

How human brain wires itself into complex networks

Screening breast MRIs can detect invasive cancers in women with history of chest irradiation

Researchers find placentas of preeclampsic women have abundance of genes linked with immune system regulation

NHGRI's new strategic plan to identify genetic bases of most single-gene disorders

New study establishes link between coronary artery disease and genetic susceptibility

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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