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Nano-biosensors along with new imaging techniques can improve drug targeting in pancreatic cancer

UK and Australian scientists have been able to show ways in which we can markedly improve drug targeting of solid tumours, using tiny 'biosensors' along with new advanced imaging techniques.

12 Jun 2013

Elevated levels of inflammatory biomarkers in individuals associated with high risk of COPD exacerbations

Simultaneously elevated levels of the biomarkers C-reactive protein, fibrinogen and leukocyte count in individuals with chronic obstructive pulmonary disease (COPD) were associated with increased risk of having exacerbations, even in those with milder COPD and in those without previous exacerbations, according to a study in the June 12 issue of JAMA.

12 Jun 2013

Scheduled exercise, regular meals and periodic warming relieve symptoms of osteoarthritis

Scheduled exercise, regular meals and the periodic warming and cooling of joints could be used to relieve the symptoms of osteoarthritis according to scientists at The University of Manchester. Their research may also help explain why older people are more prone to developing this common joint disorder.

12 Jun 2013

Celgene announces positive results from first phase III study of apremilast in psoriatic arthritis

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced 52-week results from PALACE 1, the Company's first phase III study in psoriatic arthritis at the European Congress of Rheumatology annual meeting in Madrid, Spain.

12 Jun 2013

Tumor suppressor p53 inactivation and restoration: an interview with Dr. Xin Lu, Ludwig Institute for Cancer Research

Before we talk about p53, it is important to understand why cancer cells are a problem for the body. Cancer cells multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don’t belong.

12 Jun 2013

Neuromodulators provide guidelines for implantation of "digital drugs" to manage chronic pain

Neuromodulators have joined together in the Neuromodulation Appropriateness Consensus Committee (NACC) to provide the first coordinated set of recommendations about patient selection and appropriateness for implantation of "digital drugs" to manage chronic pain.

12 Jun 2013

Viewpoints: Medicaid expansion 'makes sense'; Budget cuts hurt Alzheimer's research; Lack of transparency in generic Rx prices

The numbers in the Rand study ... should not be a surprise to people who have been paying attention. Numerous studies now, including in Missouri, have pointed to the simple reality of the policy implications of the ACA to argue for Medicaid expansion.

12 Jun 2013

Hebrew University student develops drug formulations to treat illnesses through skin applications

New, more efficient drug formulations designed to treat illnesses through skin applications -- thus avoiding serious side effects associated with oral drug-taking -- have been developed by a student at the Hebrew University of Jerusalem.

12 Jun 2013

New mobile technology could revolutionise health care in the country

A mobile phone equipped to measure heart rate, body temperature and breathing, with a digital medical manual for health care staff. Unmanned drones that can drop medicine and collect blood samples in remote areas.

12 Jun 2013

Drug development could be improved with stem cell technology, say researchers

Drug development for a range of conditions could be improved with stem cell technology that helps doctors predict the safety and the effectiveness of potential treatments.

12 Jun 2013

Obama administration changes course on Plan B

Monday afternoon, the Justice Department announced it would accept recent court rulings and begin putting into effect a judge's order to have the Food and Drug Administration certify the Plan B pill for use without prescription and without age restrictions on sales.

12 Jun 2013

Two studies shed light on joint replacement outcomes in rheumatoid arthritis patients

Two new studies by researchers at Hospital for Special Surgery have shed light on joint replacement outcomes in patients with rheumatoid arthritis. One study overturns the common belief that RA patients have worse outcomes after a total knee replacement than patients who undergo the operation for osteoarthritis. The other study demonstrates that RA patients who undergo a total hip replacement were as likely to have significant improvements in function and pain as patients with osteoarthritis, even though they did not do as well.

12 Jun 2013

Johns Hopkins researchers develop experimental vaccine for TB meningitis

A team of Johns Hopkins researchers working with animals has developed a vaccine that prevents the virulent TB bacterium from invading the brain and causing the highly lethal condition TB meningitis, a disease that disproportionately occurs in TB-infected children and in adults with compromised immune system.

12 Jun 2013

Missed savings opportunities in Medicare program

The Wall Street Journal details a report from the Department of Health and Human Services' Office of the Inspector General. Meanwhile, Kaiser Health News reports on a study that details missed savings of prescription drug costs.

12 Jun 2013

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Advanced metastatic melanoma is a disease that has proven difficult to eradicate. Despite the success of melanoma-targeting drugs, tumors inevitably become drug resistant and return, more aggressive than before. In the current issue of the journal Cancer Cell, however, researchers at The Wistar Institute describe how they increase the effectiveness of anti-melanoma drugs by combining anticancer therapies with diabetes drugs.

12 Jun 2013

Nimodipine reduces febrile seizures

Fever-induced childhood seizures, known as febrile seizures, can be terrifying for parents to witness. The full-body convulsions, which mostly affect children six months to five years old, can last from mere seconds up to more than 40 minutes. Currently, children are not treated with daily anticonvulsant medication to prevent these seizures even when they recur repeatedly because toxic side effects of existing treatments outweigh potential benefits.

12 Jun 2013

CLAAD urges FDA to implement Obama administration's policy on safer opioid medications

The Center for Lawful Access and Abuse Deterrence joined in signing a Citizen Petition filed today urging the Food and Drug Administration to fully implement the Obama administration's policy supporting a market transition to safer opioid medications.

11 Jun 2013

Surgical oncologist receives grant further explore tumor suppressor function of mutated gene

Darren Carpizo, MD, PhD, a surgical oncologist in the Liver Cancer and Bile Duct Cancer Care Program at the Cancer Institute of New Jersey, has been awarded a $200,000 grant from the Sidney Kimmel Foundation for Cancer Research to further explore the effects of a compound identified in his laboratory found to restore tumor suppressor function of a mutated gene in cancer cells.

11 Jun 2013

Study: 35% of designated drivers have high blood-alcohol levels that impair driving

Maybe better call that cab, after all: A new University of Florida study found that 35 percent of designated drivers had quaffed alcohol and most had blood-alcohol levels high enough to impair their driving.

11 Jun 2013

UCLA study shows progesterone can be used as therapy for endometrial cancer

Progesterone, a female hormone that can be used as a therapy for endometrial cancer, eliminates tumor cells indirectly by binding to its receptor in stromal or connective tissue cells residing in the tumor microenvironment, according to a study from the G.O. Discovery Lab team and collaborators at UCLA.

11 Jun 2013

Drugs News and Research

Nano-biosensors along with new imaging techniques can improve drug targeting in pancreatic cancer

Elevated levels of inflammatory biomarkers in individuals associated with high risk of COPD exacerbations

Scheduled exercise, regular meals and periodic warming relieve symptoms of osteoarthritis

Celgene announces positive results from first phase III study of apremilast in psoriatic arthritis

Tumor suppressor p53 inactivation and restoration: an interview with Dr. Xin Lu, Ludwig Institute for Cancer Research

Neuromodulators provide guidelines for implantation of "digital drugs" to manage chronic pain

Viewpoints: Medicaid expansion 'makes sense'; Budget cuts hurt Alzheimer's research; Lack of transparency in generic Rx prices

Hebrew University student develops drug formulations to treat illnesses through skin applications

New mobile technology could revolutionise health care in the country

Drug development could be improved with stem cell technology, say researchers

Obama administration changes course on Plan B

Two studies shed light on joint replacement outcomes in rheumatoid arthritis patients

Johns Hopkins researchers develop experimental vaccine for TB meningitis

Missed savings opportunities in Medicare program

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Nimodipine reduces febrile seizures

CLAAD urges FDA to implement Obama administration's policy on safer opioid medications

Surgical oncologist receives grant further explore tumor suppressor function of mutated gene

Study: 35% of designated drivers have high blood-alcohol levels that impair driving

UCLA study shows progesterone can be used as therapy for endometrial cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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