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Viewpoints: Will 'rate shock' grow?; Krugman says GOP spite is driving opposition to Medicaid expansion; Determining who owns genes

Any plausible health care reform, the various conservative alternatives to Obamacare included, would necessarily have losers as well as winners, and as far as potential losers go single young men with above-average incomes are not precisely the country's most disadvantaged demographic. If you think the current system is flawless, then I suppose any rate increase anywhere is a strike against health care reform.

10 Jun 2013

First consensus guidelines for use of neurostimulation in chronic pain

Recognizing that treatment of chronic pain can be confounding, the Neuromodulation Appropriateness Consensus Committee, an international group of more than 60 leading pain specialists, has created the first consensus guidelines for the use of neurostimulation in chronic pain.

10 Jun 2013

International experts formulate guidance for neuromodulation practitioners

An international panel of experts has formulated guidance for neuromodulation practitioners that reflects increasing recognition of the value of this growing field.

10 Jun 2013

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

10 Jun 2013

FDA panel loosens Avandia safety restrictions

Despite some concern over whether the diabetes drug Avandia can increase heart problems, an FDA panel Thursday loosened restrictions on how doctors can prescribe the drug.

10 Jun 2013

Drug regulators slow to pursue concerns about potential adverse effects of new diabetes drugs

The BMJ and Channel 4 Dispatches investigated and found that evidence suggesting potential harm from the drugs in industry studies has not been published.

10 Jun 2013

Researchers discover potential target for cancer-fighting drugs

As tumors grow, their centers are squeezed of oxygen. And so tumors must flip specific genetic switches to survive in these hypoxic environments.

10 Jun 2013

Discovery of impaired molecular pathway may help treat children with leukemia

Through genetic engineering of laboratory models, researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with leukemia as reported in the journal PNAS on June 3, 2013.

7 Jun 2013

Genetic testing of chronic neutrophilic leukemia reveals presence of new mutation in patients

A recent article in the New England Journal of Medicine describes genetic testing of a rare blood cancer called atypical chronic neutrophilic leukemia (CNL) that revealed a new mutation present in most patients with the disease.

7 Jun 2013

Available drugs may have a dramatic impact on children stricken with Tay-Sachs disease

A team of researchers has made a significant discovery which may have a dramatic impact on children stricken with Tay-Sachs disease, a degenerative and fatal neurological condition that often strikes in the early months of life.

7 Jun 2013

Cancer Institute of New Jersey offers COMET-2 clinical trial to examine cabozantinib drug

The Cancer Institute of New Jersey is one of 50 sites across the nation to offer a clinical trial known as COMET-2 that examines whether the drug cabozantinib is effective in reducing bone pain in patients with prostate cancer that is no longer responsive to hormone therapy and has spread (metastasized) to other parts of the body.

7 Jun 2013

Study suggests erectile dysfunction in young men may be more prevalent than previously thought

In a recent analysis of one outpatient clinic, one in four men seeking medical help for newly-developed erectile dysfunction (ED) was younger than 40 years, and nearly half of young men with the condition had severe ED.

7 Jun 2013

New comprehensive effort to model how humans respond to viral pathogens

In an effort to sort out why some viruses such as influenza, Ebola and West Nile are so lethal, a team of U.S. researchers plans a comprehensive effort to model how humans respond to these viral pathogens.

7 Jun 2013

Diagnoplex secures 1.3 million Swiss francs from financing round

Diagnoplex SA, a developer of molecular diagnostics for colon cancer and Debiopharm Diagnostics SA, part of the Swiss-based global biopharmaceutical group of companies Debiopharm Group™, with a focus on the development of prescription drugs that target unmet medical needs, including oncology and companion diagnostics, today announced that Diagnoplex has secured 1.3 million Swiss francs from a financing round led by Debiopharm.

7 Jun 2013

Democrats' efforts to revamp Senate filibuster rules tempered by fears on abortion votes

Some supporters of abortion rights fear that any current changes could be used sometime in the future to restrict the option for women. Meanwhile, an appeal court rules that some morning-after pills should be available over the counter immediately.

7 Jun 2013

Faster, more potent antithrombotic drugs recommended for high-risk heart attack patients

The Cardiovascular Research Laboratory of the Bellvitge Biomedical Research Institute led by the cardiologist of the Bellvitge University Hospital Jos- Luis Ferreiro has conducted a study on the effect of antiplatelet drugs given to high risk patients suffering from acute myocardial infaction (heart attack) in the context of the Infarction Code.

6 Jun 2013

New technique for developing complex protein drugs from bacteria

A cheaper, more efficient technique for developing complex protein drugs from bacteria has been developed at the University of Sheffield.

6 Jun 2013

Research reveals how HIV triggers signal to kill infected immune cell

Untreated HIV infection destroys a person's immune system by killing infection-fighting cells, but precisely when and how HIV wreaks this destruction has been a mystery until now. New research by scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, reveals how HIV triggers a signal telling an infected immune cell to die.

6 Jun 2013

Cry proteins in Bacillus thuringiensis is lethal to Anopheles gambiae, the principal mosquito vector of malaria

Researchers at The University of Texas at Dallas (UTD), led by Dr. Lee Bulla, have characterized a protein produced by the soil bacterium Bacillus thuringiensis subsp. israelensis (Bti), which is highly toxic against Anopheles gambiae, the principal mosquito vector of malaria.

6 Jun 2013

Study shows success in pinpointing individualized treatment for women with metastatic breast cancer

Funded by volleyball tournaments, a new study released this week shows success in pinpointing individualized treatment for women with metastatic breast cancer, according to George Mason University researchers.

6 Jun 2013

Drugs News and Research

Viewpoints: Will 'rate shock' grow?; Krugman says GOP spite is driving opposition to Medicaid expansion; Determining who owns genes

First consensus guidelines for use of neurostimulation in chronic pain

International experts formulate guidance for neuromodulation practitioners

Novel abnormalities in FGFR gene identified in a spectrum of cancers

FDA panel loosens Avandia safety restrictions

Drug regulators slow to pursue concerns about potential adverse effects of new diabetes drugs

Researchers discover potential target for cancer-fighting drugs

Discovery of impaired molecular pathway may help treat children with leukemia

Genetic testing of chronic neutrophilic leukemia reveals presence of new mutation in patients

Available drugs may have a dramatic impact on children stricken with Tay-Sachs disease

Cancer Institute of New Jersey offers COMET-2 clinical trial to examine cabozantinib drug

Study suggests erectile dysfunction in young men may be more prevalent than previously thought

New comprehensive effort to model how humans respond to viral pathogens

Diagnoplex secures 1.3 million Swiss francs from financing round

Democrats' efforts to revamp Senate filibuster rules tempered by fears on abortion votes

Faster, more potent antithrombotic drugs recommended for high-risk heart attack patients

New technique for developing complex protein drugs from bacteria

Research reveals how HIV triggers signal to kill infected immune cell

Cry proteins in Bacillus thuringiensis is lethal to Anopheles gambiae, the principal mosquito vector of malaria

Study shows success in pinpointing individualized treatment for women with metastatic breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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