Mouse Model News and Research

RSS

Adult brain cells may be vulnerable to Zika infection, new study suggests

Concerns over the Zika virus have focused on pregnant women due to mounting evidence that it causes brain abnormalities in developing fetuses. However, new research in mice from scientists at The Rockefeller University and La Jolla Institute for Allergy and Immunology suggests that certain adult brain cells may be vulnerable to infection as well.

24 Oct 2016

Scientists suggest potential approach of lowering tau levels to thwart Alzheimer's disease

Taking a pill that prevents the accumulation of toxic molecules in the brain might someday help prevent or delay Alzheimer's disease, according to scientists at Baylor College of Medicine, Texas Children's Hospital and Johns Hopkins University School of Medicine.

21 Oct 2016

Yale researchers develop new mouse model to understand multiple myeloma

Understanding how multiple myeloma develops and responds to therapies may be easier using a new mouse model developed at Yale University School of Medicine.

21 Oct 2016

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase.

20 Oct 2016

Research shows how mitochondrial targeting antioxidants could help treat osteoarthritis

High cholesterol might harm more than our cardiovascular systems. New research using animal models, published online in The FASEB Journal, suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis.

17 Oct 2016

Young physician-scientists win Harry Winston Fellowships for innovative pediatric research

Dr. Claire Baldauf, Dr. Marjorie-Anne Guerra and Dr. Manal Habib have been named the recipients of the 2016-2017 Harry Winston Fellowships.

14 Oct 2016

Substance NAD+ can extend life and postpone onset of aging processes

The coenzyme NAD+ plays a main role in aging processes. In mice and roundworm adding the substance can both extend life and postpone the onset of aging processes.

14 Oct 2016

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Giving mice a gene mutation linked to eating disorders in people causes feeding and behavior abnormalities similar to symptoms often seen in patients with eating disorders. Only female mice are affected by the gene mutation, and some of the abnormalities in the female mice depend on whether they are housed alone or together with other mice.

13 Oct 2016

New study unravels cause of cognitive loss in tauopathy disorders

Tauopathies are a group of neurodegenerative disorders, including Alzheimer's disease that are characterized by the deposition of aggregates of the tau protein inside brain cells.

13 Oct 2016

Visual cortex plays key role in promoting plasticity of innate, spontaneous eye movements

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex - a region of the brain known to process sensory information - plays a key role in promoting the plasticity of innate, spontaneous eye movements.

13 Oct 2016

New research reveals key protein involved in heart failure

A key protein that causes heart failure has been revealed through new research from a collaboration based in Kumamoto University, Japan.

13 Oct 2016

Study identifies mechanistic link between maternal obesity and childhood hypertension

Exposure of babies to high levels of the 'fullness' hormone, leptin, in the womb irreversibly activates receptors in the brain that regulate blood pressure, according to a new study by researchers from King's College London, part-funded by the British Heart Foundation.

12 Oct 2016

Mouse Model News and Research

Adult brain cells may be vulnerable to Zika infection, new study suggests

Scientists suggest potential approach of lowering tau levels to thwart Alzheimer's disease

Yale researchers develop new mouse model to understand multiple myeloma

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Research shows how mitochondrial targeting antioxidants could help treat osteoarthritis

Young physician-scientists win Harry Winston Fellowships for innovative pediatric research

Substance NAD+ can extend life and postpone onset of aging processes

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

New study unravels cause of cognitive loss in tauopathy disorders

Visual cortex plays key role in promoting plasticity of innate, spontaneous eye movements

New research reveals key protein involved in heart failure

Study identifies mechanistic link between maternal obesity and childhood hypertension

Common food-poisoning bacteria linked to increased risk of Crohn's disease

Researchers explain why explain why some tumors recur after immunotherapy

Researchers aim to stop breast cancer metastasis from happening altogether

Two Zika vaccine candidates protect newborn mice against neurological damage

BGU researchers elucidate molecular mechanism that could lead to new therapies for ALS

UEF research shows retinal changes may be detected earlier than brain changes

Researchers discover potential new therapeutic target for treating obesity

Study evaluates effects of spearmint, rosemary extracts on learning and memory in SAMP8 mouse model

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News