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First Edition: May 13, 2013

Today's headlines include reports that Health and Human Services Secretary Kathleen Sebelius has been seeking out funds from private sources to support efforts to publicize the health law.

13 May 2013

RA, anti-TNF drugs and abortion rates: an interview with Dr. Evelyne Vinet and Dr. Sasha Bernatsky, McGill University

Prednisone and non-steroidal anti-inflammatory drugs (NSAIDs) can be used for symptom control, but to prevent joint damage, we use disease-modifying anti-rheumatic drugs (DMARDs) including the cornerstone, methotrexate.

13 May 2013

Senate bill on FDA oversight of compounding pharmacies gets broad backing as hearings move closer

A bill to give the FDA greater authority over compounding pharmacies like the one behind a deadly meningitis outbreak gets broad -- including bipartisan -- backing, and a key committee chairman readies a hearing on the legislation.

13 May 2013

Research roundup: Out-of-pocket costs on individual market; Federal spending on mental health care; Underused Medicare benefit

Since many of the people who will gain insurance under the federal health law will likely get such individual plans through the state-based online marketplaces, or exchanges, researchers sought to identify the effects on vulnerable populations, some of whom with incomes above 400 percent of the poverty level and thus will not qualify for Medicaid or receive subsidies.

13 May 2013

Disease-in-a-dish models show promise for treating ataxia telangiectasia

Led by Dr. Peiyee Lee and Dr. Richard Gatti, researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have used induced pluripotent stem cells to advance disease-in-a-dish modeling of a rare genetic disorder, ataxia telangiectasia.

13 May 2013

Researchers identify clue to explain the reversible memory loss caused by statins

The U.S. Food and Drug Administration and physicians continue to document that some patients experience fuzzy thinking and memory loss while taking statins, a class of global top-selling cholesterol-lowering drugs.

13 May 2013

Study results suggest that CNL and aCML patients could be treated with FDA-approved drugs

Patients with two forms of leukemia, who currently have no viable treatment options, may benefit from existing drugs developed for different types of cancer, according to a study conducted by researchers at the Knight Cancer Institute at Oregon Health & Science University.

13 May 2013

Parents addicted to drugs are more likely to be depressed in adulthood

The offspring of parents who were addicted to drugs or alcohol are more likely to be depressed in adulthood, according to a new study by University of Toronto researchers.

10 May 2013

Mouse study shows leukemia halts accumulation of toxic proteins linked to Parkinson's disease

Researchers at Georgetown University Medical Center have used tiny doses of a leukemia drug to halt accumulation of toxic proteins linked to Parkinson's disease in the brains of mice. This finding provides the basis to plan a clinical trial in humans to study the effects.

10 May 2013

Study: Metformin may not improve survival rates after breast cancer

Despite previous scientific studies that suggest diabetes drug metformin has anti-cancer properties, a new, first-of-its-kind study from Women's College Hospital has found the drug may not actually improve survival rates after breast cancer in certain patients.

10 May 2013

Scientists identify new way to boost gene-silencing mechanism

A team led by scientists at The Scripps Research Institute (TSRI) has found how to boost or inhibit a gene-silencing mechanism that normally serves as a major controller of cells' activities. The discovery could lead to a powerful new class of drugs against viral infections, cancers and other diseases.

10 May 2013

Fat cells in knee secrete a protein linked to arthritis

Scientists have discovered that fat cells in the knee secrete a protein linked to arthritis, a finding that paves the way for new gene therapies that could offer relief and mobility to millions worldwide.

10 May 2013

New test determines which children with malaria are likely to develop cerebral malaria

Researchers at Michigan State University have identified a test that can determine which children with malaria are likely to develop cerebral malaria, a much more life-threatening form of the disease.

10 May 2013

ALS-ETF, Denovo partner to explore personalized medicine approach for ALS

The ALS Emergency Treatment Fund and Denovo Biomarkers have announced a partnership to explore using Denovo's technology to identify potential responder groups for drugs being studied in ALS patients.

10 May 2013

Researchers find a way the body can remove injured axons

Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the long wires that transmit signals to other parts of the body, allowing movement, sight and sense of touch, among other vital functions.

10 May 2013

Drugs News and Research

First Edition: May 13, 2013

RA, anti-TNF drugs and abortion rates: an interview with Dr. Evelyne Vinet and Dr. Sasha Bernatsky, McGill University

Senate bill on FDA oversight of compounding pharmacies gets broad backing as hearings move closer

Research roundup: Out-of-pocket costs on individual market; Federal spending on mental health care; Underused Medicare benefit

Disease-in-a-dish models show promise for treating ataxia telangiectasia

Researchers identify clue to explain the reversible memory loss caused by statins

Study results suggest that CNL and aCML patients could be treated with FDA-approved drugs

Parents addicted to drugs are more likely to be depressed in adulthood

Mouse study shows leukemia halts accumulation of toxic proteins linked to Parkinson's disease

Study: Metformin may not improve survival rates after breast cancer

Scientists identify new way to boost gene-silencing mechanism

Fat cells in knee secrete a protein linked to arthritis

New test determines which children with malaria are likely to develop cerebral malaria

ALS-ETF, Denovo partner to explore personalized medicine approach for ALS

Researchers find a way the body can remove injured axons

Cantor schedules (yet another) health law repeal vote

Expiring patents drive drug spending's first time fall

ScinoPharm Taiwan, Coland Holdings partner to develop generic oncological drugs for China

Headline results of Creabilis' CT327 Phase 2b trial in psoriasis patients announced

Pregnant teen admissions for substance abuse treatment to face greater challenges

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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