Biochemistry News and Research

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Cryo-electron microscopy helps analyze infection mechanisms of coronaviruses in detail

High-resolution cryo-electron microscopy and supercomputing have now made it possible to analyze in detail the infection mechanisms of coronaviruses. These viruses are notorious for attacking the respiratory tract of humans and animals.

27 Feb 2016

Omega-3 fatty acids can lower risk of breast cancer in postmenopausal obese women

Omega-3 fatty acids may lower the risk of breast cancer in postmenopausal obese women, according to researchers.

24 Feb 2016

SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

Researchers at the Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona (IBB-UAB), in collaboration with the biopharmaceutical company SOM Biotech, located in the Barcelona Science Park (PCB), have published, in Nature Communications, the results of a drug repositioning study in which they describe a powerful drug, SOM0226 (tolcapone) that could significantly improve the pharmacological treatment of familial transthyretin amyloidosis (ATTR).

24 Feb 2016

FSU researchers explore new method to decipher genetic data for new prostate cancer treatments

Florida State University researchers are working on new approaches to deciphering genetic data that may lead to new, more targeted prostate cancer treatments.

22 Feb 2016

Researchers identify common molecular alteration in glioblastoma

Glioblastoma is the most aggressive manifestation of brain tumours. Due to its high invasive capacity and uncontrolled, infiltrating growth, it is particularly difficult to manage. Currently, the treatment for this disease consists of a combination of surgery (when possible), radiation and chemotherapy.

22 Feb 2016

Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar

Most proteins are involved in interactions with one or a few functional ligands, but some proteins, like light chain 8 (LC8), have numerous binding partners. LC8 interacts with more than 100 functionally different proteins, from viral proteins to motor proteins to proteins involved in cell division.

From Bruker BioSpin Group 18 Feb 2016

Virginia Tech experts explore new strategy to eradicate harmful viruses

With the outbreak of viruses like Zika, chikungunya, and dengue on the rise, public health officials are desperate to stop transmission.

18 Feb 2016

Study may lead to potential drug targets for tumor formation in pulmonary tuberous sclerosis complex

In a new study published in the American Association of Cancer Research's journal Cancer Research, a pair of investigators at Rutgers and Columbia universities has identified a gene that may provide a new source of potential drug targets for tumors that arise in pulmonary tuberous sclerosis complex (TSC).

18 Feb 2016

New optogenetic technology could turn on immune cells to attack melanoma tumors

A new optogenetic technology developed at UMass Medical School, called optogenetic immunomodulation, is capable of turning on immune cells to attack melanoma tumors in mice. Using near-infrared light, UMMS researchers have shown they can selectively activate an immune response by controlling the flow of calcium ions into the cell. This breakthrough could lead to less invasive, and more controlled and selective, immunotherapies for cancer treatment.

17 Feb 2016

Small chemical change to existing antibacterial drug may result in better treatment for TB

Researchers with Vanderbilt University have discovered that one small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis.

17 Feb 2016

Synthetic RNA and DNA could reverse protein deficiency that causes Friedreich's ataxia

Researchers at UT Southwestern Medical Center have identified synthetic RNA and DNA that reverses the protein deficiency causing Friedreich's ataxia, a neurological disease for which there is currently no cure.

17 Feb 2016

Nine researchers win EPSRC Healthcare Technologies Challenge Awards

Nine researchers, working on innovative projects that promise to improve healthcare diagnosis and treatment, across a wide spread of issues, were today announced as the first recipients of the Engineering and Physical Sciences Research Council's (EPSRC) Healthcare Technologies Challenge Awards.

15 Feb 2016

Intracellular process of autophagy plays role in prostate cancer development, shows research

Research from investigators at Rutgers Cancer Institute of New Jersey and the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, shows the intracellular process of autophagy plays a role in the development of prostate cancer.

15 Feb 2016

Five researchers named winners of 2016 Elsevier Foundation Awards

Five researchers have been named winners of the 2016 Elsevier Foundation Awards for Early Career Women Scientists in the Developing World, in recognition of research that has strong potential health and economic benefits.

10 Feb 2016

Temple team describes use of cadaver DNA to advance genetics learning in medical curriculum

Cadavers have long been one of the most important resources for anatomy teaching in medical school. Now, they are also at the forefront of cutting-edge genetics teaching, thanks to innovative thinking by professors at the Lewis Katz School of Medicine at Temple University.

10 Feb 2016

Researchers find new mutation signature in cancer cells

Mutations are the replacement of DNA bases known as Adenine (A), Cytosine (C), Guanine (G) and Thymine (T) with other bases. When mutations such as C to T or G to A are found within a specific DNA sequence, this is known as a mutation signature.

10 Feb 2016

New technique allows better understanding of cellular stress reaction

Stress in the body's cells is both the cause and consequence of inflammatory diseases or cancer. The cells react to stress to protect themselves. Researchers at the University of Zurich have now developed a new technique that allows studying a fundamental response to stress in much more detail than previously possible: the ADP-ribosylation of chromatin.

9 Feb 2016

UC San Diego School of Medicine launches new NAFLD Research Center

Roughly one-quarter of all Americans - an estimated 100 million adults and children - have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure.

9 Feb 2016

New study pinpoints two tiny clusters of neurons responsible for changing normal breaths into sighs

"You must remember this: a kiss is just a kiss, a sigh is just a sigh." Contrary to the words immortalized by the piano singer in "Casablanca," a sigh is far more than a sigh. Heaving an unconscious sigh is a life-sustaining reflex that helps preserve lung function.

9 Feb 2016

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

An experimental nanoparticle therapy that combines low-density lipoproteins (LDL) and fish oil preferentially kills primary liver cancer cells without harming healthy cells, UT Southwestern Medical Center researchers report.

9 Feb 2016

Biochemistry News and Research

Cryo-electron microscopy helps analyze infection mechanisms of coronaviruses in detail

Omega-3 fatty acids can lower risk of breast cancer in postmenopausal obese women

SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

FSU researchers explore new method to decipher genetic data for new prostate cancer treatments

Researchers identify common molecular alteration in glioblastoma

Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar

Virginia Tech experts explore new strategy to eradicate harmful viruses

Study may lead to potential drug targets for tumor formation in pulmonary tuberous sclerosis complex

New optogenetic technology could turn on immune cells to attack melanoma tumors

Small chemical change to existing antibacterial drug may result in better treatment for TB

Synthetic RNA and DNA could reverse protein deficiency that causes Friedreich's ataxia

Nine researchers win EPSRC Healthcare Technologies Challenge Awards

Intracellular process of autophagy plays role in prostate cancer development, shows research

Five researchers named winners of 2016 Elsevier Foundation Awards

Temple team describes use of cadaver DNA to advance genetics learning in medical curriculum

Researchers find new mutation signature in cancer cells

New technique allows better understanding of cellular stress reaction

UC San Diego School of Medicine launches new NAFLD Research Center

New study pinpoints two tiny clusters of neurons responsible for changing normal breaths into sighs

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

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