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New insights into what causes uncontrollable bleeding in hemophilia patients

New insights into what causes uncontrollable bleeding in hemophilia patients are provided in a study published by Cell Press on November 20th in the Biophysical Journal. By revealing that blood clots spread in traveling waves through vessels, the study offers new strategies that could lead to the development of more effective treatments for hemophilia as well as common cardiovascular disorders.

20 Nov 2012

Positive results from Genentech Avastin plus temozolomide Phase III study on glioblastoma

Genentech, a member of the Roche Group, today announced results from the positive Phase III AVAglio study. The study showed Avastin (bevacizumab) in combination with radiation and temozolomide chemotherapy reduced the risk of cancer worsening or death (progression-free survival; PFS) by 36 percent compared to radiation and temozolomide chemotherapy plus placebo>th Annual Meeting of the Society for Neuro-Oncology in Washington, D.C.

19 Nov 2012

Two aspects of European approach to hypothermia rescue should be adapted and applied worldwide

Hypothermia victims whose hearts have stopped functioning should be transported to a medical facility with advanced heart and lung support equipment, even if that means longer travel time, according to a new study by a University of British Columbia medical resident.

16 Nov 2012

Cook receives FDA approval for Zilver PTX Drug-Eluting Peripheral Stent to treat PAD

The U.S. Food and Drug Administration approved the Zilver PTX Drug-Eluting Peripheral Stent (Zilver PTX Stent), the first drug-eluting stent indicated to re-open a particular artery in the thigh (femoropopliteal artery) when narrowed or blocked as a result of peripheral artery disease (PAD).

15 Nov 2012

Antibody-coated stents carry increased risk of myocardial infarction and re-operation

If narrowed or blocked coronary vessels have to be widened or opened, a vascular support (stent) is usually inserted. Drug-coated stents are preferred for patients at high risk of renewed narrowing of vessels (restenosis). However, the use of antibody-coated stents has been increasing in recent years. Current studies provide indications that these new antibody-coated stents more frequently lead to myocardial infarction and make re-operation necessary.

15 Nov 2012

Ebola, Marburg and Lassa viruses must be designated as emerging diagnoses

The Ebola, Marburg and Lassa viruses are commonly referred to as emerging diseases, but leading scientists say these life-threatening viruses have been around for centuries.

15 Nov 2012

Hydrus stent may significantly reduce eye pressure in glaucoma patients

A tiny medical device no larger than an eyelash may significantly reduce eye pressure in glaucoma patients and allow some to stop using eye-drop medications, according to year-one clinical trial results for the device.

14 Nov 2012

Tell the whole truth about implantable cardioverter-defibrillators

Consent discussions regarding the use of implantable cardioverter-defibrillators in elderly individuals rarely include the device's implications at the end of life, indicate US study results.

13 Nov 2012

Ultrasound-guided transbronchial needle aspiration complication rate ‘reassuring’

Multisite findings support the use of endobronchial ultrasound-guided transbronchial needle aspiration for mediastinal lymph node sampling.

12 Nov 2012

Close monitoring needed in year after traumatic brain injury

Patients are at particularly high risk for developing epilepsy during the first year after traumatic brain injury, a study shows.

9 Nov 2012

Patients more likely to develop ischemic stroke after total hip replacement surgeries

An international study involving the University of Southampton has shown people who undergo a total hip replacement are at a higher risk of a stroke in the first two weeks after surgery.

9 Nov 2012

Better understanding of clotting dynamics in atherosclerosis could lead to more effective drugs

The disease atherosclerosis involves the build up of fatty tissue within arterial walls, creating unstable structures known as plaques. These plaques grow until they burst, rupturing the wall and causing the formation of a blood clot within the artery. These clots also grow until they block blood flow; in the case of the coronary artery, this can cause a heart attack.

8 Nov 2012

Most patients taking common blood-thinning drugs may be receiving wrong dosage levels

Cardiology researchers at the Intermountain Medical Center Heart Institute have found that approximately 75 percent of patients taking two common blood-thinning drugs may be receiving the wrong dosage levels, according to a new study.

8 Nov 2012

Aspirin viable alternative to warfarin in preventing clots after joint replacement surgery

If you've had joint replacement surgery, it's likely you've been given warfarin, a common blood thinner and clot-preventer, prior to surgery. While effective, research from the Rothman Institute at Jefferson has shown aspirin to be just as effective in preventing clots, specifically pulmonary emboli, life-threatening blood clots that can develop in the arteries of the lungs following joint replacement surgery.

8 Nov 2012

WU researchers to study blood-clotting disorders

Researchers at Washington University School of Medicine in St. Louis have received a $9 million grant to investigate blood-clotting disorders. From heart attacks and strokes to uncontrolled bleeding, clotting disorders cause more deaths each year in the United States than all types of cancer combined.

7 Nov 2012

Elafin protein protects against inflammatory diseases

This protection is provided by a human protein, Elafin, which is artificially introduced into dairy produce bacteria (Lactococcus lactis and Lactobacillus casei). In time, this discovery could be useful for individuals suffering from chronic inflammatory diseases such as Crohn's disease or ulcerative colitis.

7 Nov 2012

Scientists identify group of small molecules that interfere with polyphosphate activity

Scientists have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins or arteries, a condition called thrombosis. Blocking the activity of this compound, polyphosphate, could treat thrombosis with fewer bleeding side effects than the drugs that are currently on the market.

7 Nov 2012

Low-dose aspirin effective at preventing serious blood clots

Low-dose aspirin is a cheap and effective way to prevent potentially deadly blood clots in the leg or the lungs in patients who have had a previous blood clot a new study shows.

6 Nov 2012

Imaging-based therapy benefits ‘wake-up stroke’ patients

Undertaking thrombolysis on the basis of magnetic resonance imaging findings in patients with stroke of unknown onset time may double their chances for a good outcome, say researchers.

5 Nov 2012

Pradaxa use does not appear to increase serious bleeding

The U.S. Food and Drug Administration (FDA) today announced the results of a Mini-Sentinel assessment that indicates bleeding rates associated with new use of Pradaxa (dabigatran etexilate mesylate) capsules do not appear to be higher than bleeding rates associated with new use of warfarin, which is consistent with observations from the pivotal RE-LY trial.

4 Nov 2012

Bleeding News and Research

New insights into what causes uncontrollable bleeding in hemophilia patients

Positive results from Genentech Avastin plus temozolomide Phase III study on glioblastoma

Two aspects of European approach to hypothermia rescue should be adapted and applied worldwide

Cook receives FDA approval for Zilver PTX Drug-Eluting Peripheral Stent to treat PAD

Antibody-coated stents carry increased risk of myocardial infarction and re-operation

Ebola, Marburg and Lassa viruses must be designated as emerging diagnoses

Hydrus stent may significantly reduce eye pressure in glaucoma patients

Tell the whole truth about implantable cardioverter-defibrillators

Ultrasound-guided transbronchial needle aspiration complication rate ‘reassuring’

Close monitoring needed in year after traumatic brain injury

Patients more likely to develop ischemic stroke after total hip replacement surgeries

Better understanding of clotting dynamics in atherosclerosis could lead to more effective drugs

Most patients taking common blood-thinning drugs may be receiving wrong dosage levels

Aspirin viable alternative to warfarin in preventing clots after joint replacement surgery

WU researchers to study blood-clotting disorders

Elafin protein protects against inflammatory diseases

Scientists identify group of small molecules that interfere with polyphosphate activity

Low-dose aspirin effective at preventing serious blood clots

Imaging-based therapy benefits ‘wake-up stroke’ patients

Pradaxa use does not appear to increase serious bleeding

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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