Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Haploidentical bone marrow transplants for sickle cell disease: an interview with Dr. Javier Bolaños Meade

Bone marrow transplant (also called stem cell transplant) is a medical intervention that allows a physician to deliver very high doses of chemotherapy (if needed) but more importantly, deliver a new immune system to the patient to fight a disease (such as cancer).

3 Oct 2012

New insights on mechanisms involved in regeneration of insulin-producing cells

Researchers at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute have found that a blood vessel-building gene boosts the ability of human bone marrow stem cells to sustain pancreatic recovery in a laboratory mouse model of insulin-dependent diabetes.

3 Oct 2012

Study examines newly proposed DSM-5 criteria for autism spectrum disorder

Parents should not worry that proposed changes to the medical criteria redefining a diagnosis of autism will leave their children excluded and deemed ineligible for psychiatric and medical care, says a team of researchers led by psychologists at Weill Cornell Medical College.

3 Oct 2012

BHGI sponsors global summit on international breast health

For women with breast cancer in low- and middle-resource countries and other medically underserved areas around the world, the need for supportive care and the consideration of quality-of-life issues are often overlooked.

2 Oct 2012

Novel therapy shows promise in treating multiple myeloma following stem cell transplants

A novel therapy in the early stages of development at Virginia Commonwealth University Massey Cancer Center shows promise in providing lasting protection against the progression of multiple myeloma following a stem cell transplant by making the cancer cells easier targets for the immune system.

2 Oct 2012

Lilly announces new data from two Phase II ramucirumab trials on NSCLC

Eli Lilly and Company today announced new data from two Phase II ramucirumab (IMC-1121B) trials in patients with non-small cell lung cancer (NSCLC).

1 Oct 2012

Researchers reduce life-threatening complication of stem cell transplants in mice with leukemia

Studying leukemia in mice, researchers at Washington University School of Medicine in St. Louis have reduced a life-threatening complication of stem cell transplants, the only curative treatment when leukemia returns.

28 Sep 2012

EC approves Janssen’s DACOGEN for treatment of de novo acute myeloid leukaemia

Janssen-Cilag International NV announced today that the European Commission has approved the marketing authorisation for DACOGEN(decitabine) for the treatment of adult patients (age 65 years and above) with newly diagnosed de novo or secondary acute myeloid leukaemia (AML), according to the World Health Organisation (WHO) classification, who are not candidates for standard induction chemotherapy.

28 Sep 2012

UCSD receives NCI grant to continue research into chronic lymphocytic leukemia

An international consortium of scientists studying chronic lymphocytic leukemia (CLL), based at the University of California, San Diego School of Medicine, has been awarded a 5-year, $20 million grant by the National Cancer Institute, part of the National Institutes of Health.

28 Sep 2012

ARIAD Pharmaceuticals completes rolling submission of ponatinib NDA with FDA

ARIAD Pharmaceuticals, Inc. today announced it has completed the rolling submission of the New Drug Application (NDA) for its investigational BCR-ABL inhibitor, ponatinib, to the U.S. Food and Drug Administration (FDA).

28 Sep 2012

Go Daddy donates $10,000 for Scottsdale Healthcare Cancer Center fundraiser

GoDaddy.com, the world's largest provider of Web hosting and domain name registrations, is donating $10,000 to help cancer patients and kick-start fundraising for the 4th annual Scottsdale Healthcare Rob Moy Memorial Motorcycle Run.

27 Sep 2012

NCI-funded sequencing project aims to identify genetic links to colorectal cancer

Uncovering colon cancer's genetic roots is the focus of a new $13 million, four-year, National Cancer Institute-funded project at Fred Hutchinson Cancer Research Center. Ulrike (Riki) Peters, Ph.D., M.P.H., a member of the Hutchinson Center's Public Health Sciences Division, will lead the effort. She and her colleagues will use next-generation sequencing, a technique that captures entire genome sequences, to identify genetic links to colorectal cancer.

27 Sep 2012

NOXXON commences NOX-A12 Phase IIa trial in relapsed MM

NOXXON Pharma today announced the treatment of the first cohort of three multiple myeloma (MM) patients in a Phase IIa clinical trial of its anti-CXCL12/SDF-1 (CXC chemokine ligand 12 / Stromal Cell-Derived Factor-1) Spiegelmer NOX-A12.

26 Sep 2012

Cell Banker 3 cryopreservation solution effectively preserves iPSCs

In a study to determine the best cryopreservation (freezing) solution to maintain induced pluripotent stem (iPS) cells, a team of researchers from Japan compared 12 kinds of commercially prepared and readily available cryopreservation solutions and found that "Cell Banker 3" out-performed the other 11 solutions by allowing iPS cells to be preserved for a year at -80 degrees C in an undifferentiated state.

26 Sep 2012

UC Medicine nurses to administer free flu shots to licensed taxicab drivers at O'Hare Midway

As part of an initiative to vaccinate some of Chicago's most vulnerable populations, University of Chicago Medicine nurses will administer free flu shots to licensed taxicab drivers at O'Hare International Airport on Tuesday, Sept. 25, and at Midway International Airport the following Tuesday, Oct. 2. Up to 1,000 cabbies could be vaccinated over the two days.

25 Sep 2012

Study unlocks secrets in bone marrow that could lead to improved treatments for colitis, Crohn's

Michigan State University researchers have unlocked secrets in bone marrow that could lead to improved treatments for colitis and Crohn's disease.

25 Sep 2012

Bone marrow transplants hold promise for sickle cell patients

Research shows that even partially matched bone marrow transplants are able to eliminate sickle cell disease in some patients with sickle cell anemia.

24 Sep 2012

$Encouraging results from CTI’s pacritinib phase 1 study on relapsed/refractory lymphoma$

Encouraging results from CTI’s pacritinib phase 1 study on relapsed/refractory lymphoma

Cell Therapeutics, Inc. announced today that the phase 1 study data of its highly selective oral JAK2 inhibitor pacritinib, or SB1518, showed encouraging anti-tumor activity and good tolerability in 34 patients with relapsed/refractory lymphoma.

24 Sep 2012

Even partially matched bone marrow transplants can eliminate sickle cell disease in some patients

In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painful and debilitating symptoms and the need for a lifetime of pain medications and blood transfusions.

24 Sep 2012

Simple survey can effectively identify women with ovarian cancer symptoms

A simple three-question paper-and-pencil survey, given to women in the doctor's office in less than two minutes, can effectively identify those who are experiencing symptoms that may indicate ovarian cancer, according to a study by researchers at Fred Hutchinson Cancer Research Center.

24 Sep 2012

Bone Marrow News and Research

Further Reading

Haploidentical bone marrow transplants for sickle cell disease: an interview with Dr. Javier Bolaños Meade

New insights on mechanisms involved in regeneration of insulin-producing cells

Study examines newly proposed DSM-5 criteria for autism spectrum disorder

BHGI sponsors global summit on international breast health

Novel therapy shows promise in treating multiple myeloma following stem cell transplants

Lilly announces new data from two Phase II ramucirumab trials on NSCLC

Researchers reduce life-threatening complication of stem cell transplants in mice with leukemia

EC approves Janssen’s DACOGEN for treatment of de novo acute myeloid leukaemia

UCSD receives NCI grant to continue research into chronic lymphocytic leukemia

ARIAD Pharmaceuticals completes rolling submission of ponatinib NDA with FDA

Go Daddy donates $10,000 for Scottsdale Healthcare Cancer Center fundraiser

NCI-funded sequencing project aims to identify genetic links to colorectal cancer

NOXXON commences NOX-A12 Phase IIa trial in relapsed MM

Cell Banker 3 cryopreservation solution effectively preserves iPSCs

UC Medicine nurses to administer free flu shots to licensed taxicab drivers at O'Hare Midway

Study unlocks secrets in bone marrow that could lead to improved treatments for colitis, Crohn's

Bone marrow transplants hold promise for sickle cell patients

Encouraging results from CTI’s pacritinib phase 1 study on relapsed/refractory lymphoma

Even partially matched bone marrow transplants can eliminate sickle cell disease in some patients

Simple survey can effectively identify women with ovarian cancer symptoms

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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