Malignant News and Research

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Up to 10% of acute lung injuries may be drug-related

A population-based study has found that drug-induced acute lung injury accounts for around 9.5% of all acute lung injury cases.

23 Oct 2012

Breast cancer spread dependent on both environment and genetic changes

A new study from Johns Hopkins researchers suggests that the lethal spread of breast cancer is as dependent on a tumor’s protein-rich environment as on genetic changes inside tumor cells.

23 Oct 2012

Glioblastoma multiforme can originate from cortical neurons

Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in Science Express, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

23 Oct 2012

Malignant melanoma cases increase in Sweden

Malignant melanoma is as much as 35% more common among people who live in Gothenburg and the region's coastal municipalities than those who live inland. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have found that the number of malignant melanoma cases in the Västra Götaland region has quadrupled since 1970.

22 Oct 2012

Ultrasound superior to mammography in evaluating women with breast cancer symptoms

The largest analysis to date comparing ultrasound and mammography to evaluate women ages 30 to 39 with symptoms of possible breast cancer concludes that ultrasound is a superior diagnostic tool and that U.S. clinical practice guidelines, which currently recommend mammography as the first evaluation in these women, should be reconsidered.

22 Oct 2012

New diagnostic tool identifies metastatic ability of breast cancer cells

Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) and The Institute of Photonic Sciences (ICFO) have collaborated on the development of a diagnostic tool that identifies the metastatic ability of breast cancer cells.

20 Oct 2012

New video on how to handle Malignant Hyperthermia crisis now available from MHAUS

New video on how to handle a Malignant Hyperthermia crisis is now available from the Malignant Hyperthermia Association of the United States.

20 Oct 2012

Weill Cornell Medical College researcher wins 2012 William B. Coley Award

Dr. Laurie H. Glimcher, the Stephen and Suzanne Weiss Dean of Weill Cornell Medical College and provost for medical affairs of Cornell University, is a winner of the 2012 William B. Coley Award for Distinguished Research in Basic Immunology from the Cancer Research Institute for her outstanding achievements in immunology and cancer research.

19 Oct 2012

UMB, UMCP to develop small robot that could help neurosurgeons in removing brain tumors

A research team from the University of Maryland, College Park (UMCP) and the University of Maryland, Baltimore (UMB) have been awarded a new $2 million grant from the National Institutes of Health (NIH) to continue developing a small robot that could one day be a huge aid to neurosurgeons in removing difficult-to-reach brain tumors.

17 Oct 2012

First analysis of IASLC malignant pleural mesothelioma database

The International Mesothelioma Interest Group (IMIG) staging system has been widely used, however, widespread concerns exist about the validity of the current malignant pleural mesothelioma (MPM) staging system.

16 Oct 2012

Researcher uncovers mechanisms involved in prognosis of acute myeloid leukemia

When patients suffering from Acute Myeloid Leukemia (AML) express high levels of the gene, MN1, an already aggressive leukemia is accelerated and shortens survival time. While that's a known fact, the mechanisms involved aren't well understood which is why a Wake Forest Baptist Medical Center researcher decided to take a closer look.

16 Oct 2012

Bidirectional communication between breast cancer cells and nearby MSCs cause metastasis

In recent years investigators have discovered that breast tumors are influenced by more than just the cancer cells within them. A variety of noncancerous cells, which in many cases constitute the majority of the tumor mass, form what is known as the "tumor microenvironment."

12 Oct 2012

Investigators provide overview of role of dopamine in modulating the immune system

Dopamine is a neurotransmitter that is associated with emotions, movement, and the brain's pleasure and reward system. In the current issue of Advances in Neuroimmune Biology, investigators provide a broad overview of the direct and indirect role of dopamine in modulating the immune system and discuss how recent research has opened up new possibilities for treating diseases such as Parkinson's and Alzheimer's disease, schizophrenia, multiple sclerosis or even the autoimmune disorders.

11 Oct 2012

Tissue test detects oral cancer risk

A molecular diagnostic scoring system based on patients’ FOXM1-associated gene messenger RNA expression levels is able to quantitatively diagnose and stratify oral carcinoma and its aggressiveness, show UK and Norwegian study results.

11 Oct 2012

New research lists cell stiffness as possible biomarker for metastatic ovarian cancer

New Georgia Tech research shows that cell stiffness could be a valuable clue for doctors as they search for and treat cancerous cells before they're able to spread. The findings, which are published in the journal PLoS One, found that highly metastatic ovarian cancer cells are several times softer than less metastatic ovarian cancer cells.

11 Oct 2012

Fibulin-3 protein may help identify mesothelioma in early stages

Researchers at NYU School of Medicine have discovered the protein product of a little-known gene may one day prove useful in identifying and monitoring the development of mesothelioma in early stages, when aggressive treatment can have an impact on the progression of disease and patient prognosis.

11 Oct 2012

Aspirin associated with reduced risk of serious ovarian cancer

New research shows that women who regularly use pain relief medications, particularly aspirin, have a decreased risk of serious ovarian cancer—an aggressive carcinoma affecting the surface of the ovary.

10 Oct 2012

MRI method ‘cuts breast cancer false‑positives’

Assessing apparent diffusion coefficients during dynamic contrast-enhanced magnetic resonance imaging may reduce the number of avoidable false‑positive breast cancer results and unnecessary biopsies, show findings published in Radiology.

9 Oct 2012

RXi receives SBIR grant to enable discovery and preclinical development of sd-rxRNAs

RXi Pharmaceuticals Corporation, a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted technologies, today announced that it was awarded a Small Business Innovation Research (SBIR) grant by the National Cancer Institute (NCI) of the National Institutes of Health (NIH).

5 Oct 2012

New gene test can detect pre-cancerous cells in patients with mouth lesions

Researchers from Queen Mary, University of London have developed a new gene test that can detect pre-cancerous cells in patients with benign-looking mouth lesions. The test could potentially allow at-risk patients to receive earlier treatment, significantly improving their chance of survival.

5 Oct 2012

Malignant News and Research

Up to 10% of acute lung injuries may be drug-related

Breast cancer spread dependent on both environment and genetic changes

Glioblastoma multiforme can originate from cortical neurons

Malignant melanoma cases increase in Sweden

Ultrasound superior to mammography in evaluating women with breast cancer symptoms

New diagnostic tool identifies metastatic ability of breast cancer cells

New video on how to handle Malignant Hyperthermia crisis now available from MHAUS

Weill Cornell Medical College researcher wins 2012 William B. Coley Award

UMB, UMCP to develop small robot that could help neurosurgeons in removing brain tumors

First analysis of IASLC malignant pleural mesothelioma database

Researcher uncovers mechanisms involved in prognosis of acute myeloid leukemia

Bidirectional communication between breast cancer cells and nearby MSCs cause metastasis

Investigators provide overview of role of dopamine in modulating the immune system

Tissue test detects oral cancer risk

New research lists cell stiffness as possible biomarker for metastatic ovarian cancer

Fibulin-3 protein may help identify mesothelioma in early stages

Aspirin associated with reduced risk of serious ovarian cancer

MRI method ‘cuts breast cancer false‑positives’

RXi receives SBIR grant to enable discovery and preclinical development of sd-rxRNAs

New gene test can detect pre-cancerous cells in patients with mouth lesions

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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