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Study examines effect of low-dose vancomycin to treat clostridium difficile infection

Clostridium difficile infection (CDI) is inflammation of the colon caused by a bacteria called clostridium difficile and is the most common cause of infectious diarrhea in hospitalized patients.

8 Dec 2020

Phase I/IIA open-label study presents encouraging results on hard-to-treat AML subtypes

Novel menin-KMT2A inhibitor appears to be safe and well-tolerated. FLT3 inhibitor plus low-dose chemotherapy shows promising efficacy and safety. Results represent encouraging news on hard-to-treat AML subtypes.

7 Dec 2020

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

A team of researchers at the Feinberg School of Medicine demonstrated that xylitol and grapefruit seed extract (GSE) could prevent SARS-CoV-2 infection. These can be used as a nasal spray to contain the spread of the coronavirus.

7 Dec 2020

Potential SARS-CoV-2 Mpro inhibitors identified by in silico screening

The search for effective inhibitors of SARS-CoV-2 is assuming new urgency as the fall/winter resurgence of the infection appears.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

Study proposes new plan to help reduce financial hardships for cancer patients

Until you or a loved one are facing treatment for a cancer diagnosis, you may not realize the cost associated with treatment and doctor visits.

6 Dec 2020

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

Affecting almost 600,000 people worldwide every year, and with only a 50% survival rate, oral squamous cell carcinoma (OSCC) is one of the more common and deadly forms of cancer.

4 Dec 2020

Is mask-wearing effective in preventing SARS-CoV-2 transmission?

UK-based researchers released the findings of their review of the efficacy of the face coverings and masks in preventing transmission of coronavirus disease 2019 (COVID-19).

4 Dec 2020

Study offers hope to parents and kids who face real danger from peanut exposure

It's a peanut-filled world--or at least it can feel that way for kids with peanut allergies. But a new study by researchers at the University of British Columbia and BC Children's Hospital gives hope to parents and kids who face real danger from exposure to peanuts.

3 Dec 2020

Researchers create first map of microbiome of dental black plaque in adults

The dark pigmentations that appear around the gums on dental enamel have a bacterial origin and there is currently no definitive therapy to remove it entirely.

3 Dec 2020

New combination therapy may help fight antimicrobial resistance

An inexpensive, FDA-approved drug -- cholestyramine -- taken in conjunction with an antibiotic prevents the antibiotic from driving antimicrobial resistance, according to new research by scientists at Penn State and the University of Michigan. The team's findings appear today (Dec. 1) in the journal eLife.

2 Dec 2020

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Dana-Farber Cancer Institute researchers will present more than 40 research studies at the virtual 62nd American Society of Hematology Annual Meeting on December 5-8, including two studies that were selected for inclusion in the official press program.

1 Dec 2020

Direct oral anticoagulant does not appear to offer protection against severe COVID-19

DOAC (direct oral anticoagulant) pills are used in the treatment of atrial fibrillation by preventing blood clots. Even though blood clots are thought to contribute to complications from the new coronavirus infection, users of this class of drug do not seem to be protected against severe COVID-19, reports a large Swedish registry study from Karolinska Institutet published in The Journal of Internal Medicine.

1 Dec 2020

COVID-19 restrictions have led to 86 percent drop in norovirus infections in US, finds study

The onset of the COVID-19 pandemic led to the imposition of several non-pharmaceutical interventions (NPIs) across the world. While citizens in the USA have been chafing over the advice to wear masks in public, restricted social interactions, and limited attendance at schools, colleges and workplaces, a new study published on the preprint server medRxiv* in November 2020 reports that these NPIs were linked to a steep reduction in the incidence of the non-respiratory pathogen, noroviruses.

1 Dec 2020

Overcoming pediatric drug-resistant TB crisis

World Children's Day marks the day, over three decades ago, on which world leaders adopted the historic Convention of the Rights of the Child, promising to every child to promote and protect their rights, including the right to life and the right to health.

30 Nov 2020

Oral News and Research

Study examines effect of low-dose vancomycin to treat clostridium difficile infection

Phase I/IIA open-label study presents encouraging results on hard-to-treat AML subtypes

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

Potential SARS-CoV-2 Mpro inhibitors identified by in silico screening

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Study proposes new plan to help reduce financial hardships for cancer patients

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

Is mask-wearing effective in preventing SARS-CoV-2 transmission?

Study offers hope to parents and kids who face real danger from peanut exposure

Researchers create first map of microbiome of dental black plaque in adults

New combination therapy may help fight antimicrobial resistance

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Direct oral anticoagulant does not appear to offer protection against severe COVID-19

COVID-19 restrictions have led to 86 percent drop in norovirus infections in US, finds study

Overcoming pediatric drug-resistant TB crisis

Asymptomatic patients have higher SARS-CoV-2 viral loads than symptomatic patients, study says

Novel cannabis plant extracts could protect against COVID-19

Iron infusion highly effective to treat anemia in low-income settings

Sex steroids may play a protective role in COVID-19, shows study

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