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Moffitt researchers analyze participation rate of patients in pharmacogenomic trials

Cancer therapy has evolved from a "one-size-fits-all" type of treatment plan to a personalized approach based on a patient's type of cancer, the protein and genetic markers found in their tumors and their response to therapy. Important aspects of the personalized approach are pharmacogenomic studies that analyze associations between genetic variations and patient drug responses.

29 Jul 2015

Lidocaine benefits breast cancer survivors who experience pain during intercourse

Scientists at Oregon Health & Science University report that breast cancer survivors who experience pain during sexual intercourse, a common side effect of breast cancer treatment, may achieve comfort when liquid lidocaine is applied strategically to prevent pain.

28 Jul 2015

Yale researchers confirm NF1 gene as major player in development of skin cancer

A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies.

28 Jul 2015

Protein imbalances within cells can cause ovarian cancer

Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found. The discovery is a major breakthrough because, until now, genetic aberrations have been seen as the main cause of almost all cancer.

28 Jul 2015

Girls are born with weaker spines compared to boys, study finds

Looking at measurements of the vertebrae - the series of small bones that make up the spinal column - in newborn children, investigators at Children's Hospital Los Angeles found that differences between the sexes are present at birth. Results of the study, now online in advance of publication in the August issue of the Journal of Pediatrics, suggest that this difference is evolutionary, allowing the female spine to adapt to the fetal load during pregnancy.

25 Jul 2015

Moffitt researchers develop genetic test that analyzes sensitivity of tumors to radiation therapy

Recent advances in the understanding of cancer have led to more personalized therapies, such as drugs that target particular proteins and tests that analyze gene expression patterns in tumors to predict a patient's response to therapy.

24 Jul 2015

Deep Genomics set to bring the power of deep learning technologies to genomics

Evolution has altered the human genome over hundreds of thousands of years -- and now humans can do it in a matter of months.

23 Jul 2015

Experts to highlight new diagnostic products, tools to identify heart attacks at 2015 AACC Annual Meeting

The 2015 AACC Annual Meeting & Clinical Lab Expo, the leading annual event for laboratory medicine, will open on Sunday, July 26, in Atlanta, Georgia. This year's meeting will host more than 400 educational sessions on topics ranging from personalized medicine and infectious diseases to point-of-care and laboratory-developed tests, and will feature more than 200 new cutting edge diagnostic products.

23 Jul 2015

MD Anderson named one of Genome Characterization Centers

The University of Texas MD Anderson Cancer Center has been named a site for one of two new Genome Characterization Centers (GCC) funded through the National Cancer Institute.

23 Jul 2015

Infants born with mutation in PLVAP gene develop severe protein losing enteropathy

Newborn children born with a mutation in the Plasmalemma Vesicle Associated Protein (PLVAP) gene develop severe protein losing enteropathy, according to a case study1 published in Cellular and Molecular Gastroenterology and Hepatology, the basic science journal of the American Gastroenterological Association.

23 Jul 2015

Genetic variation influences survival in patients with multiple myeloma

As part of a multi-institutional effort, researchers with Huntsman Cancer Institute at the University of Utah have found that multiple myeloma patients with a genetic variation in the gene FOPNL die on average 1-3 years sooner than patients without it.

23 Jul 2015

Drug addiction expert uncovers molecular mechanisms that contribute to addiction resistance

Growing up in West Virginia, Jill Turner saw firsthand the kind of havoc that drug addiction can wreak. "I had a lot of friends who had very promising lives and promising careers ahead of them," the assistant professor in the South Carolina College of Pharmacy says, "but they ended up either overdosing or going to jail for drug-related stuff. It's one of the reasons I went into drug addiction research."

22 Jul 2015

Multi-year project aims to develop, improve clinical research tools for studying ASD

Government, non-profit, and other private partners will fund a multi-year project to develop and improve clinical research tools for studying autism spectrum disorder (ASD). The project will receive a total of $28 million over the next four years to test and refine clinical measures of social impairment in ASD in order to better evaluate potential behavioral and drug therapies.

22 Jul 2015

NeoGenomics announces launch of new germline cancer predisposition testing services

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today the launch of a new line of germline cancer predisposition testing services. The new tests include comprehensive testing for BRCA1 and BRCA2 encompassing an analysis of all exons and adjacent intronic regions.

20 Jul 2015

Transcranial magnetic stimulation holds promise for tinnitus patients

In the largest U.S. clinical trial of its kind funded by the Veterans Affairs Rehabilitation Research and Development Service, researchers at the VA Portland Medical Center and Oregon Health & Science University found that transcranial magnetic stimulation significantly improved tinnitus symptoms for more than half of study participants.

17 Jul 2015

Medtronic launches GenCut Core Biopsy System for minimally invasive use with the superDimension navigation system for lung tissue biopsies

Medtronic now offers the GenCut(TM) core biopsy system, a unique lung tissue biopsy tool for use with the superDimension(TM) navigation system. The superDimension(TM) system enables a minimally invasive approach to accessing difficult-to-reach areas of the lung, which can aid in the diagnosis of lung cancer.

From Medtronic 17 Jul 2015

Research breakthrough opens door to a world of regenerative medicine for treating mitochondrial disease

A study led by Shoukhrat Mitalipov, Ph.D., and Hong Ma, M.D., Ph.D., at the Center for Embryonic Cell and Gene Therapy at Oregon Health & Science University and the Oregon National Primate Research Center has revealed the first critical step in developing novel gene and stem cell therapy treatments for patients with mitochondrial disease.

16 Jul 2015

Restore Health's specialty pharmacy division seeks accreditation from URAC

Restore Health, a company specializing in personalized medicine, announced today that its specialty pharmacy division is in the process of seeking accreditation from URAC, a Washington, D.C.-based healthcare accrediting organization that establishes quality standards for the healthcare industry.

14 Jul 2015

QIAGEN's therascreen EGFR RGQ PCR Kit to guide use of IRESSA for in NSCLC treatment

QIAGEN N.V. today received U.S. marketing (PMA) approval of its therascreen EGFR RGQ PCR Kit (therascreen EGFR test) as a companion diagnostic to guide the use of AstraZeneca's IRESSA (gefitinib) in the treatment of patients with advanced or metastatic non-small cell lung cancer (NSCLC).

From QIAGEN Manchester Limited 14 Jul 2015

Shape of the cerebral cortex strongly correlates with genetic ancestry

Researchers at the University of California, San Diego and the School of Medicine have found that the three-dimensional shape of the cerebral cortex - the wrinkled outer layer of the brain controlling many functions of thinking and sensation - strongly correlates with ancestral background.

12 Jul 2015

Precision Medicine News and Research

Moffitt researchers analyze participation rate of patients in pharmacogenomic trials

Lidocaine benefits breast cancer survivors who experience pain during intercourse

Yale researchers confirm NF1 gene as major player in development of skin cancer

Protein imbalances within cells can cause ovarian cancer

Girls are born with weaker spines compared to boys, study finds

Moffitt researchers develop genetic test that analyzes sensitivity of tumors to radiation therapy

Deep Genomics set to bring the power of deep learning technologies to genomics

Experts to highlight new diagnostic products, tools to identify heart attacks at 2015 AACC Annual Meeting

MD Anderson named one of Genome Characterization Centers

Infants born with mutation in PLVAP gene develop severe protein losing enteropathy

Genetic variation influences survival in patients with multiple myeloma

Drug addiction expert uncovers molecular mechanisms that contribute to addiction resistance

Multi-year project aims to develop, improve clinical research tools for studying ASD

NeoGenomics announces launch of new germline cancer predisposition testing services

Transcranial magnetic stimulation holds promise for tinnitus patients

Medtronic launches GenCut Core Biopsy System for minimally invasive use with the superDimension navigation system for lung tissue biopsies

Research breakthrough opens door to a world of regenerative medicine for treating mitochondrial disease

Restore Health's specialty pharmacy division seeks accreditation from URAC

QIAGEN's therascreen EGFR RGQ PCR Kit to guide use of IRESSA for in NSCLC treatment

Shape of the cerebral cortex strongly correlates with genetic ancestry

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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