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Researchers identify gene mutations responsible for subtype of childhood brain tumor

The St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project has identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients.

15 Apr 2013

Drug makers must change R&D practices or patent disputes will continue

"[T]he impact of [a decision by the Supreme Court in India to disallow a new patent for an updated version of Novartis' cancer drug Glivec] will likely be broader than just that issue, escalating a long-simmering fight over patented cancer medications in emerging markets," Thomas Bollyky, senior fellow for global health, economics, and development at the Council on Foreign Relations and an adjunct professor of law at Georgetown University, writes in an Atlantic opinion piece.

15 Apr 2013

FDA grants Fast Track designation to Elorac's naloxone topical lotion

Elorac, Inc., a rapidly growing specialty pharmaceutical company focused on the treatment of dermatological disorders, announced that the U.S. Food and Drug Administration has granted Fast Track designation to the Company's naloxone topical lotion for the relief of pruritus in patients with cutaneous T-cell lymphoma.

15 Apr 2013

Ameritox study shows correlation between positive marijuana tests, misuse of prescription drugs

Ameritox, one of the nation's leaders in pain medication monitoring, announced new research today showing a correlation between positive marijuana tests and higher rates of potential prescription drug non-adherence among chronic pain medication users.

15 Apr 2013

Genetic analysis of H7N9 portrays that virus evolves to adapt to human cells

A genetic analysis of the avian flu virus responsible for at least nine human deaths in China portrays a virus evolving to adapt to human cells, raising concern about its potential to spark a new global flu pandemic.

15 Apr 2013

Researchers create complete visual map of telomerase enzyme

Like finally seeing all the gears of a watch and how they work together, researchers from UCLA and UC Berkeley have, for the first time ever, solved the puzzle of how the various components of an entire telomerase enzyme complex fit together and function in a three-dimensional structure.

15 Apr 2013

State highlights: Baby boomers eye expanding end-of-life rights in states across nation; Calif. judges threaten governor with contempt of court over prison care

Claudia Burzichelli doesn't want to die like her dad. … In states across the country, including New Jersey, Connecticut, Massachusetts and Vermont, graying baby boomers have been lobbying lawmakers in recent months at hearings, in letters and by phone, pushing to make it legal for doctors to prescribe life-ending drugs to terminally ill patients.

15 Apr 2013

Research roundup: Lesson for insurance exchanges from Europe; Health care disparities among Hispanics

As states and the federal government begin creating insurance exchanges under the health law, researchers highlight several lessons from Switzerland and the Netherlands.

15 Apr 2013

Pharmacological study shows interactions between drugs can be detected with minute doses

Clinical pharmacologists at Heidelberg University Hospital have achieved major progress for improving the reliability of drugs. In a pharmacological study, they showed for the first time that interactions between drugs can be detected with minute doses in the range of nanograms.

15 Apr 2013

First Edition: April 12, 2013

Today's headlines include reports about a new study measuring how the health law has expanded young adults access to care.

12 Apr 2013

Novel nanoparticle-based approach enables more efficient delivery of siRNA drugs

New classes of drugs that can silence specific genes, such as small interfering RNAs (siRNAs), offer great therapeutic potential. But the specific delivery of siRNAs to target cells to exert their effects remains a significant challenge. A novel nanoparticle-based approach that enables more efficient delivery of siRNA drugs is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

12 Apr 2013

Study reveals inner workings of master regulator that controls diverse functions

New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" themselves in response to external stimuli and the mechanism by which certain viruses hijack normal cellular processes to facilitate their replication that can ultimately lead to cancer. The research will be published in the April 12, 2013 issue of the Journal of Biological Chemistry.

12 Apr 2013

Researchers identify new potential therapeutic target for lowering cholesterol

Researchers at the University of Michigan have identified a new potential therapeutic target for lowering cholesterol that could be an alternative or complementary therapy to statins.

12 Apr 2013

New process to create malaria drug artemisinin should provide stable supply, reduce cost, researchers report

"U.S. scientists on Wednesday said they had used baker's yeast to make a key ingredient of malaria drugs, a feat that could iron out fluctuations in supply caused by sourcing the chemical from a Chinese herb," Artemisia annua, Agence France-Presse reports (4/10).

12 Apr 2013

Sanofi launches large-scale production of artemisinin for malaria

Twelve years after a breakthrough discovery in his University of California, Berkeley, laboratory, professor of chemical engineering Jay Keasling is seeing his dream come true.

12 Apr 2013

Protein EPAC2 plays major role in development of type 2 diabetes

A team of researchers at the Johns Hopkins Children's Center has found that a protein long believed to have a minor role in type 2 diabetes is, in fact, a central player in the development of the condition that affects nearly 26 million people in the United States alone and counts as one of the leading causes of heart disease, stroke and kidney, eye and nerve damage.

12 Apr 2013

ATSP-9172 exhibits on-target binding activity in human prostate cancer model

Aileron Therapeutics, Inc. today announced new preclinical data demonstrating that ATSP-9172, its Stapled Peptide inhibitor of HIF-1α-dependent transcription, exhibits on-target binding activity, favorable pharmacokinetic properties and potent in vivo efficacy in a human prostate cancer model.

12 Apr 2013

People with apple-shaped bodies more likely to develop kidney disease

High blood pressure in the kidneys of people with apple-shaped bodies may be responsible for their increased risk of developing kidney disease later in life, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

12 Apr 2013

Antipsychotics seemed to normalize gene expression pattern in people with bipolar disorder: Study

Every day, millions of people with bipolar disorder take medicines that help keep them from swinging into manic or depressed moods.

12 Apr 2013

Researchers unravel dual role of tumor necrosis factor in TB

Tumor necrosis factor - normally an infection-fighting substance produced by the body- can actually heighten susceptibility to tuberculosis if its levels are too high.

12 Apr 2013

Drugs News and Research

Researchers identify gene mutations responsible for subtype of childhood brain tumor

Drug makers must change R&D practices or patent disputes will continue

FDA grants Fast Track designation to Elorac's naloxone topical lotion

Ameritox study shows correlation between positive marijuana tests, misuse of prescription drugs

Genetic analysis of H7N9 portrays that virus evolves to adapt to human cells

Researchers create complete visual map of telomerase enzyme

State highlights: Baby boomers eye expanding end-of-life rights in states across nation; Calif. judges threaten governor with contempt of court over prison care

Research roundup: Lesson for insurance exchanges from Europe; Health care disparities among Hispanics

Pharmacological study shows interactions between drugs can be detected with minute doses

First Edition: April 12, 2013

Novel nanoparticle-based approach enables more efficient delivery of siRNA drugs

Study reveals inner workings of master regulator that controls diverse functions

Researchers identify new potential therapeutic target for lowering cholesterol

New process to create malaria drug artemisinin should provide stable supply, reduce cost, researchers report

Sanofi launches large-scale production of artemisinin for malaria

Protein EPAC2 plays major role in development of type 2 diabetes

ATSP-9172 exhibits on-target binding activity in human prostate cancer model

People with apple-shaped bodies more likely to develop kidney disease

Antipsychotics seemed to normalize gene expression pattern in people with bipolar disorder: Study

Researchers unravel dual role of tumor necrosis factor in TB

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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