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Researchers identify molecular cascade that drives sprouting in brain after stroke

A stroke wreaks havoc in the brain, destroying its cells and the connections between them. Depending on its severity and location, a stroke can impact someone's life forever, affecting motor activity, speech, memories, and more.

11 Nov 2010

Genetic constitution can influence changes in tumor growth: Study

The genes we possess not only determine the color of our eyes and hair and how our bodies grow, they might also influence the changes that occur in tumors when we develop cancer.

11 Nov 2010

Exhausted neurons die prematurely and trigger disease symptoms

We all know that living a stressful lifestyle can take its toll, making us age faster and making us more susceptible to the cold going around the office.

11 Nov 2010

Childhood asthma risk linked with prenatal paracetamol exposure depends on antioxidant genes in mother

Evidence suggesting that the risk of childhood asthma associated with prenatal paracetamol exposure may depend on antioxidant genes in the mother has been found by a team of UK scientists. The results of their study - which strengthens the argument for a causal link between paracetamol exposure in early life and later childhood asthma - are published online (10 November) in the Journal of Allergy and Clinical Immunology.

11 Nov 2010

New discovery can develop diagnostic test to identify gene mutation in AML

Decoding the DNA of a woman who died of acute myeloid leukemia (AML) has led researchers at Washington University School of Medicine in St. Louis to a gene that they found to be commonly altered in many patients who died quickly of the disease.

11 Nov 2010

Dietary intervention reduces emergence of diabetes-predictive autoantibodies by 50%

A Finnish study published in the November 11, 2010 issue of the New England Journal of Medicine confirms the hypothesis that infant feeding plays a role in the initiation of the disease process leading to type 1 diabetes in children carrying increased genetic disease risk.

11 Nov 2010

New 'magic bullet' can eradicate side effects of drug used to treat cystinosis

A 'magic bullet' designed by pharmaceutical scientists at an English university could eradicate the side effects of a drug used to treat a rare genetic disease. Researchers at the University of Sunderland have chemically modified a drug used to treat cystinosis a disease which occurs when the body's mechanism to remove excess cystine (an amino acid) breaks down, leading to kidney problems and eventually affecting other organs to remove unpleasant side effects such as nausea, vomiting, severe halitosis, body odour and a noxious taste.

11 Nov 2010

Depression associated with molecular-level disturbance in body's 24-hour clock

Depression appears to be associated with a molecular-level disturbance in the body's 24-hour clock, new research suggests.

11 Nov 2010

Epimutation in BRCA1 gene may cause early-onset of breast cancer

An Australian research team from the Peter MacCallum Cancer Centre, the University of Melbourne and the University of Queensland has identified a new risk factor for developing breast cancer. This has been published online in the journal Cancer Prevention Research.

10 Nov 2010

Lung cancer in smokers versus non-smokers shows different genetic mutations

A group of scientists at B.C. Cancer Agency have found that lung cancers in smokers have different genetic mutations and look different than lung cancer in non-smokers. According to senior scientist at the BC Cancer Agency Research Centre Wan Lam, this finding is significant because it means that from now on, research, treatments and diagnostics should be tailored to the distinct genetic variations in the different lung cancers instead of expecting that a one-size fits all approach will work. He said, “At the current time, treatment does not distinguish between these different types. The subtypes are all grouped together. But with this work, we are beginning to tease out the subtypes.” The study was presented Tuesday at a conference in Philadelphia of the American Association of Cancer Research.

10 Nov 2010

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Using proton pump inhibitors and antiplatelet drugs (thienopyridines) together is an appropriate way of treating patients with cardiovascular disease who are at high risk of upper gastrointestinal bleeds, despite recent concerns about an adverse interaction between these two types of drugs, according to an Expert Consensus Document released jointly today by the American College of Cardiology Foundation, the American College of Gastroenterology, and the American Heart Association.

10 Nov 2010

Researchers identify molecular cascade that drives process of reconnection in adult brain after stroke

10 Nov 2010

Conference of The MacLean Center for Clinical Medical Ethics to focus on health disparities

The 22nd annual conference of The MacLean Center for Clinical Medical Ethics at the University of Chicago will be held at the University of Chicago Law School, 1111 E. 60th Street, on Fri., Nov. 12, from 1 to 5 pm, and Sat., Nov. 13, from 7:30 am to 5:15 pm.

10 Nov 2010

Article shows link between maternal cigarette smoking during pregnancy, SIDS

The link between maternal cigarette smoking during pregnancy and Sudden Infant Death Syndrome may relate to the negative effects of nicotine on the development of brain centers that regulate breathing, according to an article in the recent issue of Pediatric Allergy, Immunology, and Pulmonology, a peer-reviewed journal published by Mary Ann Liebert, Inc.

10 Nov 2010

Jefferson awarded $2.6M grant for study on cognitive decline in older African Americans with MCI

Researchers in the Departments of Psychiatry and Neurology at Jefferson Medical College of Thomas Jefferson University were recently awarded a $2.6 million grant from The National Institute of Health to study whether increasing participation in cognitive, physical and/or social activities prevents cognitive decline in older African Americans with Mild Cognitive Impairment (MCI).

10 Nov 2010

Researcher awarded Sylvia and Charles Viertel Charitable Foundation Fellowship

Walter and Eliza Hall Institute researcher Dr Ross Dickins has been awarded a Sylvia and Charles Viertel Charitable Foundation Fellowship worth $AUD975,000 over five years.

10 Nov 2010

Contraceptive, antiviral gel using bee venom wins 2010 Gates Foundation grant

A vaginal gel that affords both contraception and HIV protection using nanoparticles that carry bee venom is one of the bold, unconventional ideas that won a 2010 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation.

10 Nov 2010

Grand Challenges Explorations projects receive new grants for tuberculosis research

Weill Cornell Medical College announced today that it was awarded two $100,000 grants from the Bill & Melinda Gates Foundation as part of the next phase of Grand Challenges Explorations, an initiative to encourage bold and unconventional ideas for global health.

10 Nov 2010

Study finds cancer cells subject to several major chromosomal changes at the same time

New progress has been made on the road to understanding the origins of genetic changes in tumour cells. The prevalent theory has been that genetic changes in tumour cells come about in multiple stages over a long time. However, a recent study by researchers at Lund University shows that this does not have to be the case at all, but that the cancer cells instead can be subject to several major chromosomal changes at the same time.

9 Nov 2010

Innovative method for in-cell gene manipulation

A cross-disciplinary Small Medicine and Advanced Research Translation (SMART) team led by Prof. Dar-Bin Shieh of Institute of Oral Medicine in Medical College at National Cheng Kung University (NCKU), Tainan, Taiwan, has announced a breakthrough in the precision in-cell gene scission at pre-designed sequence sites using Artificial Targeting Light Activated Nano Scissors (ATLANS) and a custom build photonic device.

9 Nov 2010

Genetic News and Research

Researchers identify molecular cascade that drives sprouting in brain after stroke

Genetic constitution can influence changes in tumor growth: Study

Exhausted neurons die prematurely and trigger disease symptoms

Childhood asthma risk linked with prenatal paracetamol exposure depends on antioxidant genes in mother

New discovery can develop diagnostic test to identify gene mutation in AML

Dietary intervention reduces emergence of diabetes-predictive autoantibodies by 50%

New 'magic bullet' can eradicate side effects of drug used to treat cystinosis

Depression associated with molecular-level disturbance in body's 24-hour clock

Epimutation in BRCA1 gene may cause early-onset of breast cancer

Lung cancer in smokers versus non-smokers shows different genetic mutations

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Researchers identify molecular cascade that drives process of reconnection in adult brain after stroke

Conference of The MacLean Center for Clinical Medical Ethics to focus on health disparities

Article shows link between maternal cigarette smoking during pregnancy, SIDS

Jefferson awarded $2.6M grant for study on cognitive decline in older African Americans with MCI

Researcher awarded Sylvia and Charles Viertel Charitable Foundation Fellowship

Contraceptive, antiviral gel using bee venom wins 2010 Gates Foundation grant

Grand Challenges Explorations projects receive new grants for tuberculosis research

Study finds cancer cells subject to several major chromosomal changes at the same time

Innovative method for in-cell gene manipulation

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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