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Understanding the role of astrocytic G protein-coupled receptors in substance-use disorders

A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs).

5 Mar 2025

Exploring the relationship between non-coding RNAs and oxidative stress in cancer progression

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that drive tumor development.

5 Mar 2025

Global study sheds light on differences in medicine taste sensitivity

Many medicines taste so bitter that some people avoid taking them. To help with the bad taste, flavors and sweeteners are added to modify the taste and make it more acceptable.

4 Mar 2025

Semen quality linked to longevity in men

Men's semen quality is associated with how long they live according to a study of nearly 80,000 men, which is published today (Wednesday) in Human Reproduction, one of the world's leading reproductive medicine journals.

4 Mar 2025

High-resolution DNA sequencing data for 37,000 children and parents released

The first resource containing high-resolution DNA sequencing data for over 37,000 children and parents collected over multiple decades from across the UK is now available to researchers worldwide.

4 Mar 2025

HPV more common in men than women and linked to rising cancer rates

While the human papillomavirus (HPV) is most associated with cervical cancer risk and women, a new survey commissioned by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) shows that the majority of people are unaware that the virus is actually more common among men than women and is associated with rising rates of other cancers that directly impact men.

4 Mar 2025

New Arab Pangenome Reference promises advancements in precision medicine

Creation of a comprehensive genetic representation for more than 2.5 billion people across the Middle East and South Asia could make a major contribution towards advancing precision medicine, a publication in Nature Medicine reveals.

4 Mar 2025

New CRISPR-enriched metagenomics method for detecting antibiotic resistance genes in wastewater

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals.

4 Mar 2025

Study provides a comprehensive cellular map of how diabetes disrupts bone immune interactions

When we think of type 2 diabetes, images of heart problems or kidney damage often come to mind. But lurking quietly behind these well-known complications is another serious threat—bone disease.

4 Mar 2025

Breakthrough study sheds light on Pol-theta’s role in DNA repair and cancer

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these proteins-called polymerase theta (Pol-theta)-for their own survival.

4 Mar 2025

Study explores gene interactions in Alzheimer's disease across brain regions

Alzheimer's disease (AD), a neurodegenerative disorder marked by amyloid plaque buildup and cognitive decline, remains a challenging condition to understand at the molecular level.

4 Mar 2025

Surprising study reveals dads’ weight and diet don’t impact baby’s size

A study shows paternal health factors like BMI and diet do not influence birth weight or length, emphasizing maternal diet's critical role in pregnancy.

4 Mar 2025

Researchers uncover genetic basis of aggressive prostate cancer

Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.

3 Mar 2025

Epstein-Barr virus infection predisposes people to develop Crohn's disease

Crohn's disease, a debilitating inflammatory bowel disease, has many known contributing factors, including bacterial changes in the microbiome that foster an inflammatory environment.

3 Mar 2025

Groundbreaking studies reveal how DNA folding guides sperm cell development

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell.

3 Mar 2025

Co-occurring mutations may limit effectiveness of KRAS G12C inhibitors in colorectal and pancreatic cancer

Colorectal cancer and pancreatic ductal adenocarcinoma that harbored the KRAS G12C mutation often carried other genetic alterations that can be associated with resistance to KRAS G12C inhibitors, despite no prior treatment with this therapy, according to recent results from a large multidatabase analysis.

3 Mar 2025