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Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A Salk Institute discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead to a treatment for Alzheimer's disease based on a compound found in nature.

21 Feb 2019

Peripheral nerve injury can trigger the onset and spread of ALS, shows study

A growing collection of anecdotal stories raises the possibility that nerve injury in an arm or a leg can act as a trigger for the development amyotrophic lateral sclerosis, or ALS -- a progressive neurodegenerative disease also known as Lou Gehrig's disease, named after the famous New York Yankee who died of it in 1941.

20 Feb 2019

New, versatile technique for remote control of transplanted cells in Parkinson's

Neurodegenerative conditions such as Parkinson’s disease are a major public health issue, especially given the ageing population in Europe and beyond. Parkinson’s now affects more than 1 900 people per 100 000 among those aged 80 and older.

20 Feb 2019

Scientists probe into the mind of worms to unravel how memories form

Try as you might, some events cannot be remembered. Known in psychology as memory blocking, the phenomenon has remained elusive since first described more than half a century ago.

20 Feb 2019

Researchers create new map of the brain's own immune system

A team of researchers under the direction of the Medical Center - University of Freiburg has created an entirely new map of the brain's own immune system in humans and mice.

19 Feb 2019

Newly developed stem cell technologies show promise for treating PD patients

Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

15 Feb 2019

Researchers identify brain pathways of aversion

What happens in the brain when we feel discomfort? Researchers at Karolinska Institutet in Sweden are now one step closer to finding the answer. In a new study published in the journal Molecular Psychiatry they identify which pathways in the mouse brain control behavior associated with aversion.

14 Feb 2019

Exercise gives a better brain boost to older men than women

New research suggests that the relationship between physical and brain fitness varies in older adults by virtue of their sex. The study is published ahead of print in the Journal of Applied Physiology.

13 Feb 2019

Rapid progression of age-related diseases may result from formation of vicious cycles

Biologist Aleksey Belikov from the Moscow Institute of Physics and Technology has proposed that rapid progression of age-related diseases may result from the formation of so-called vicious cycles. An example of this is when toxic products of a biochemical reaction trigger that same reaction to happen again.

12 Feb 2019

Human brain protein linked with autism has an effect on fruit fly behavior

A mutant gene that encodes a brain protein in a child with autism has been placed into the brains of fruit flies. Fruit flies hosting that gene produce the variant human brain protein and show abnormal behaviors of fear, repetitive activity and altered social interaction, reminiscent of autism impairments.

12 Feb 2019

Brain protein critical to recovery from stroke identified

Every 40 seconds, someone in the United States suffers a stroke and available therapies, such as clot busting drugs or clot removal devices, are focused on limiting the extent of brain damage.

12 Feb 2019

Watchful waiting in prostate cancer becoming more popular

In 2010, the US National Comprehensive Cancer Network guidelines suggested that patients with stable and low-risk prostate cancers could be managed with active surveillance or watchful waiting (AS/WW). AS/WW was considered to be a safe and effective alternative to aggressive surgery to remove the prostate and radiation therapy.

11 Feb 2019

New target appears to aid recovery after optic nerve trauma

When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report.

11 Feb 2019

Mosquitoes can hear over distances much greater than suspected before

Mosquitoes can hear over distances much greater than anyone suspected, according to researchers at Cornell and Binghamton University.

11 Feb 2019

Alzheimer's disease protection from exercise hormone irisin

Irisin is found to be protective against Alzheimer’s disease finds a new study. The results of the new study were published in the journal Nature Medicine.

11 Feb 2019

Scientists create 3D-bioprinted brain model to study interaction with immune cells

Around a glioblastoma, a very aggressive brain tumor, cells of the human immune system start helping the tumor instead of attacking it. To do research on what happens in the interaction of these cells, scientists of the University of Twente now created a 3D-bioprinted mini model of the brain.

11 Feb 2019

Experts explore involvement of the gut in Parkinson's disease

There is growing evidence that at least in some patients with Parkinson's disease (PD), the disease may begin in the gut. Writing in a special supplement to the Journal of Parkinson's Disease, experts explore the last two decades of research about the gut-brain axis in PD and look ahead at the possible development and impact of these research areas in the next two decades.

8 Feb 2019

Researchers show efficacy of new therapy for amyotrophic lateral sclerosis in mice

A team from Université Laval and the CERVO Brain Research Centre has demonstrated the efficacy in mice of a new therapy that addresses the main manifestation of amyotrophic lateral sclerosis.

7 Feb 2019

Making the Most of Microdialysis for Neurotransmitter Analysis

Martin Eysberg provides an introduction to the ALEXYS Neurotransmitter Analyzer, an extremely precise UHPLC-EC detector for neurotransmitter analysis.

From Antec Scientific 6 Feb 2019

ALS and Tow Foundation announce their continuing support to New York Genome Center

The ALS Association and The Tow Foundation are pleased to announce their continuing support of the New York Genome Center's Center for Genomics of Neurodegenerative Disease, in recognition of the substantial genomic research being carried out by NYGC scientists.

6 Feb 2019