Neurons News and Research

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Revival of the cell and gene therapy field opens new avenues for repairing the Parkinsonian brain

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored.

21 Sep 2021

Discovery points toward a new strategy for treating Parkinson’s disease

University of Utah Health scientists have identified a molecule that slows cells’ production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson’s disease.

21 Sep 2021

Researchers create a living bioengineered nerve circuit to tackle opioid overdose crisis

In 2019, nearly 50,000 people in the United States died from opioid overdoses, bringing the total of number of deaths from the opioid crisis to half a million over the past 10 years, according to the U.S. Centers for Disease Control.

21 Sep 2021

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

An opinion article aims to provide evidence that SP could be the possible factor for initiating the cytokine storm during severe SARS-CoV-2 infection.

21 Sep 2021

Light exposure during pregnancy may be linked to fetal brain development

There may be a link between exposure to light during pregnancy and fetal brain development. New findings by researchers at Umeå University, Sweden, working in collaboration with American colleagues, may provide better understanding of certain neurological diseases later in life.

20 Sep 2021

Cross-species locomotion features shared by dopamine-deficient worms, mice, and humans

Scientists from the Graduate School of Information Science and Technology at Osaka University used animal location tracking along with artificial intelligence to automatically detect walking behaviors of movement disorders that are shared across species.

18 Sep 2021

New automated computer program can accurately count micronuclei in cells

Micronuclei, which are small nucleus-like structures within cells, are commonly associated with tumors. Now, researchers from Tsukuba, Japan have developed an automated computer program that can accurately and reproducibly count these structures from microscope images, which will increase the speed and accuracy of micronuclei research.

18 Sep 2021

Sex defining factors influence expression of ACE2 and other SARS-CoV-2 machinery

Results from this study provided evidence for the hypothesis that sex-defining factors influence the expression of ACE2 and other SARS CoV-2 machinery.

17 Sep 2021

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Gliomas are the most common primary brain tumors in adults. Among them, high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them. The disease rapidly progresses to an advanced stage in a short span of time, and the survival of such patients is often dismal.

16 Sep 2021

Researchers identify key factor responsible for brain development during evolution

As humans, we have a large and intricately folded neocortex that accounts for many of our intellectual abilities and sets us apart from all other species

16 Sep 2021

Scientists investigate if the APOE4 gene in astrocytes relates to Alzheimer's disease

AD, the most frequent cause of dementia, affects an estimated 24 million people worldwide. With very limited treatment options, scientists are looking for ways to understand the disease better.

15 Sep 2021

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

Autism affects about 2% of children in the United States, and about 30% of these children have seizures. Recent large-scale genetic studies revealed that genetic variants in a sodium channel, called voltage-gated sodium channel Nav1.2, is a leading cause of autism.

15 Sep 2021

Brain changes may explain the profound altered behavior associated with LSD

Lysergic acid diethylamide, or LSD, is a potent hallucinogen that alters the perception of reality. Researchers at Baylor College of Medicine have discovered changes in the brain, triggered by the drug, that may explain the profound altered behavior associated with LSD, helping to understand how the brain generates behavior.

15 Sep 2021

Cholesterol appears to play a key role in the development of Alzheimer’s disease

Cholesterol manufactured in the brain appears to play a key role in the development of Alzheimer's disease, new research indicates.

14 Sep 2021

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.

13 Sep 2021

Study offers molecular insights into how toxic proteins are regulated in brain diseases

Rutgers researchers have discovered some of the first molecular insights into how toxic proteins are regulated in neurodegenerative diseases such as Alzheimer's and Parkinson's.

13 Sep 2021

Study reveals blood metabolites associated with dementia

Scientists in Japan have identified metabolic compounds within the blood that are associated with dementia.

12 Sep 2021

Salt tasting cells drive food foraging strategy in nematode worms

Neuroscientists have developed a computer model to explain how a nematode worm searches for food, revealing that single brain cells can both sense the environment and control a whole animal's foraging strategy.

9 Sep 2021

High fat diets break the body clock in rats leading to over-eating and obesity

When rats are fed a high fat diet, this disturbs the body clock in their brain that normally controls satiety, leading to over-eating and obesity. That's according to new research published in The Journal of Physiology.

7 Sep 2021

Study sheds light on neurologic symptoms caused by SARS-CoV-2 infection

Researchers in Australia and Finland have provided important insights into how infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – might affect nervous system circuitries and cause neurologic symptoms.

6 Sep 2021

Neurons News and Research

Revival of the cell and gene therapy field opens new avenues for repairing the Parkinsonian brain

Discovery points toward a new strategy for treating Parkinson’s disease

Researchers create a living bioengineered nerve circuit to tackle opioid overdose crisis

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

Light exposure during pregnancy may be linked to fetal brain development

Cross-species locomotion features shared by dopamine-deficient worms, mice, and humans

New automated computer program can accurately count micronuclei in cells

Sex defining factors influence expression of ACE2 and other SARS-CoV-2 machinery

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Researchers identify key factor responsible for brain development during evolution

Scientists investigate if the APOE4 gene in astrocytes relates to Alzheimer's disease

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

Brain changes may explain the profound altered behavior associated with LSD

Cholesterol appears to play a key role in the development of Alzheimer’s disease

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

Study offers molecular insights into how toxic proteins are regulated in brain diseases

Study reveals blood metabolites associated with dementia

Salt tasting cells drive food foraging strategy in nematode worms

High fat diets break the body clock in rats leading to over-eating and obesity

Study sheds light on neurologic symptoms caused by SARS-CoV-2 infection

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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