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Roche, Isis Pharmaceuticals to develop neurodegenerative therapeutics for Huntington's disease

Roche and Isis Pharmaceuticals, Inc today announced that they have formed an alliance to develop treatments for Huntington's disease based on Isis' antisense oligonucleotide technology.

9 Apr 2013

Argentina's ANMAT approves AUBAGIO for patients with relapsing multiple sclerosis

Genzyme, a Sanofi company, announced today Argentina's National Administration of Drugs, Food and Medical Technology has approved once-daily, oral AUBAGIO 14 mg as a new treatment indicated for patients with relapsing forms of multiple sclerosis.

9 Apr 2013

Viewpoints: Drugging soldiers; GOP opposition to Medicaid expansion strays from party legacy; Health law distorts market

Last year, more active-duty soldiers committed suicide than died in battle. ... Worse, according to data not reported on until now, the military evidently responded to stress that afflicts soldiers in Iraq and Afghanistan primarily by drugging soldiers on the front lines.

9 Apr 2013

Johns Hopkins researchers find how gout-linked genetic mutation contributes to disease

Johns Hopkins scientists have found out how a gout-linked genetic mutation contributes to the disease: by causing a breakdown in a cellular pump that clears an acidic waste product from the bloodstream.

9 Apr 2013

Study offers new insights into how nervous system processes hot and cold temperatures

A study from the University of North Carolina School of Medicine offers new insights into how the nervous system processes hot and cold temperatures. The research led by neuroscientist Mark J. Zylka, PhD, associate professor of cell biology and physiology, found an interaction between the neural circuits that detect hot and cold stimuli: cold perception is enhanced when nerve circuitry for heat is inactivated.

9 Apr 2013

Obama's budget expected to call for Medicare cuts

n advance of the release of President Barack Obama's fiscal blueprint on Wednesday, an adviser warned friends and foes that the plan includes things neither will like. The budget plan is expected to kick off new discussions about trimming entitlements and revamping the nation's safety net.

9 Apr 2013

New drug combination shows anti-cancer activity in patients with solid tumors and germline mutation

A novel combination of two drugs has shown anti-cancer activity in patients who had incurable solid tumors and carried a germline mutation in their BRCA genes, Dana-Farber Cancer Institute researchers are reporting at the American Association for Cancer Research annual meeting in Washington, April 6-10.

8 Apr 2013

Study evaluates efficacy of drug combinations in treating colorectal cancer

Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Once colorectal cancer has spread to other parts of the body, only 11 percent of patients will survive five years from the date of their diagnosis.

8 Apr 2013

Researchers identify four genes newly associated with severe childhood obesity

Researchers have identified four genes newly associated with severe childhood obesity. They also found an increased burden of rare structural variations in severely obese children.

8 Apr 2013

Blood test reveals more gene mutations in cancer than traditional tumor biopsy

A new blood test revealed more of the gene mutations that sustain certain digestive-tract tumors than did a DNA analysis of a traditional tumor biopsy, Dana-Farber Cancer Institute investigators will report at a special symposium of the American Association for Cancer Research annual meeting in Washington, April 6-10.

8 Apr 2013

Physician-researcher to lead pediatric Dream Team to create new treatments for childhood cancers

A physician-researcher from The Children's Hospital of Philadelphia will lead the first-ever pediatric "Dream Team" solely focused on creating new treatments for the most challenging childhood cancers.

8 Apr 2013

Dual-signaling CAR T cells show potent anti-cancer activity in animal model

The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs.

8 Apr 2013

Research identifies important role of zinc in kidney stone formation

Kidney stones usually make their presence known suddenly, often sending a person to the hospital in excruciating pain. Each year in the U.S. more than a million people seek medical attention for kidney stones, technically called nephrolithiasis.

8 Apr 2013

Mannitol could lead to new approach for Parkinson's disease treatment, researchers suggest

Researchers from Tel Aviv University describe experiments that could lead to a new approach for treating Parkinson's disease using a common sweetener, mannitol.

8 Apr 2013

Review: Impact of TBI on sexuality and importance of rehabilitation strategies

Each year more than three million Americans are living with traumatic brain injury (TBI), a condition that is associated with physical, cognitive, and emotional problems that often affect their sexuality, and subsequently their marital stability, identity, and self-esteem.

7 Apr 2013

First Korean/U.S. workshop on drug regulation and marketing

Getting more and better drugs to market for patients was the ultimate goal of the University of Maryland School of Pharmacy's first Korean/U.S. workshop on drug regulation and marketing from March 18 to 22.

6 Apr 2013

Research shows diabetes trials worldwide failing to address key issues relating to condition

An analysis of diabetes trials worldwide has found they are not addressing key issues relating to the condition with almost two thirds focusing on drug therapy while only one in ten addresses prevention or behavioural therapies.

6 Apr 2013

India's Supreme Court ruling on drug patent will promote affordable medicines, 'preserve' innovation incentives

Noting that India's Supreme Court on Monday ruled that drug maker Novartis "should not be given a patent for a cancer drug because it was too similar to Novartis's earlier version," a New York Times editorial writes, "The decision, which is the culmination of a high-profile, seven-year legal battle, should help protect the availability of cheap generic drugs for poor patients."

6 Apr 2013

Researcher awarded NIH grant to study drug-related health disparities in African-Americans

Your body's ability to effectively respond to stress may be an indicator of your vulnerability to use and abuse drugs.

6 Apr 2013

Fruit fly study offers clues to wound healing

A person's skin and a fruit fly's exoskeleton, called a "cuticle" may not look alike, but both coverings protect against injury, infection, and dehydration.

6 Apr 2013

Drugs News and Research

Roche, Isis Pharmaceuticals to develop neurodegenerative therapeutics for Huntington's disease

Argentina's ANMAT approves AUBAGIO for patients with relapsing multiple sclerosis

Viewpoints: Drugging soldiers; GOP opposition to Medicaid expansion strays from party legacy; Health law distorts market

Johns Hopkins researchers find how gout-linked genetic mutation contributes to disease

Study offers new insights into how nervous system processes hot and cold temperatures

Obama's budget expected to call for Medicare cuts

New drug combination shows anti-cancer activity in patients with solid tumors and germline mutation

Study evaluates efficacy of drug combinations in treating colorectal cancer

Researchers identify four genes newly associated with severe childhood obesity

Blood test reveals more gene mutations in cancer than traditional tumor biopsy

Physician-researcher to lead pediatric Dream Team to create new treatments for childhood cancers

Dual-signaling CAR T cells show potent anti-cancer activity in animal model

Research identifies important role of zinc in kidney stone formation

Mannitol could lead to new approach for Parkinson's disease treatment, researchers suggest

Review: Impact of TBI on sexuality and importance of rehabilitation strategies

First Korean/U.S. workshop on drug regulation and marketing

Research shows diabetes trials worldwide failing to address key issues relating to condition

India's Supreme Court ruling on drug patent will promote affordable medicines, 'preserve' innovation incentives

Researcher awarded NIH grant to study drug-related health disparities in African-Americans

Fruit fly study offers clues to wound healing

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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