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Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

Concert Pharmaceuticals, Inc. today announced that it has entered into a Cooperative Research and Development Agreement with the Walter Reed Army Institute of Research. The CRADA will allow the WRAIR to conduct preclinical testing on a novel compound derived from Concert's DCE Platform™ (deuterated chemical entity platform) for seizure protection associated with traumatic brain injury, a major public health concern.

3 Feb 2011

FDA disallows obesity drug Contrave pending further large-scale testing

In its latest blow to obesity medication development efforts, the US Food and Drug Administration (FDA) yesterday notified Orexigen Therapeutics that it would need to conduct an extremely large-scale study of the long-term cardiovascular effects of its drug, Contrave, before approval could be considered.

3 Feb 2011

Four-gene/protein signature more accurately predicts metastatic prostate cancer

Prostate tumors that carry a "signature" of four molecular markers have the potential to become dangerously metastatic if not treated aggressively, researchers at Dana-Farber Cancer Institute report in a study published online today by the journal Nature. The discovery lays the groundwork for the first gene-based test for determining whether a man's prostate cancer is likely to remain dormant within the prostate gland, or spread lethally to other parts of the body.

3 Feb 2011

Researchers discover potential vaccine capable of reducing H. pylori colonization

A new study led by researchers at Rhode Island Hospital in collaboration with the University of Rhode Island and EpiVax. Inc, a privately owned vaccine development company in Providence, RI, has identified a potential vaccine capable of reducing colonization of Helicobacter pylori -- a known cause of gastritis, ulcer disease and cancer.

2 Feb 2011

Bill Gates' annual letter calls for focus on eradicating polio, governments to sustain foreign aid

Bill Gates, co-chair of the Bill & Melinda Gates Foundation, "urged developed nations to help him wipe out polio 'once and for all' at an event to release his third annual letter [.pdf] Monday," Agence France-Presse reports.

2 Feb 2011

New research: Antioxidants in pecans may prevent development of various diseases

A new research study from Loma Linda University demonstrates that naturally occurring antioxidants in pecans may help contribute to heart health and disease prevention; the results are published in the January 2011 issue of The Journal of Nutrition.

2 Feb 2011

Economists suggest new approach to monitor nutrition, child mortality in developing countries

In a paper published in the January issue of the journal Economics and Human Biology, a team of applied economists including William A. Masters, a professor at the Friedman School of Nutrition Science and Policy at Tufts University, suggests a new approach to monitoring the relationship between nutrition and child mortality in developing countries.

2 Feb 2011

Roundup: Medicaid worries in Texas, Ill., Pa.; California insurance exchanges; Kansas controversy on health law

The current state House and Senate budget proposals include a 10 percent cut in the rate that the state will pay Medicaid providers. Some health care lobbying groups say that when you add in the loss of the enhanced federal Medicaid match paid for by stimulus dollars that have now dried up, you get a 33 percent reduction overall.

2 Feb 2011

New Spanish version of ASPIRE for Hispanic teens

The University of Texas MD Anderson Cancer Center's popular web-based teen prevention and smoking-cessation program, ASPIRE, now speaks Spanish.

2 Feb 2011

Surge of mosquito borne disease in South Australia following wet weather

Rising water in the Murray River has caused a surge in mosquito-borne infections in South Australia. The water is rising in the Murray in SA as floodwaters move downstream from the eastern states.

2 Feb 2011

Scientists test new dry powder measles vaccine that can be inhaled

Sustained high vaccination coverage is key to preventing deaths from measles. Despite the availability of a vaccine, measles remains an important killer of children worldwide, particularly in less-developed regions where vaccination coverage is limited. A team of researchers, led by scientists at the Johns Hopkins Bloomberg School of Public Health and the University of Colorado, developed and successfully tested a dry powder, live-attenuated measles vaccine that can be inhaled.

2 Feb 2011

Scientists successfully crystallise key norovirus enzyme

With the number of norovirus infection cases rising across the country, scientists from the University of Southampton have successfully crystallised a key norovirus enzyme, which could help in the development of a norovirus treatment.

1 Feb 2011

Elsevier announces publication of two position statements from EMAS in Maturitas journal

Elsevier announced today the publication of two further important position statements from the European Menopause and Andropause Society in the journal Maturitas on common management problems in the post-reproductive health of women.

1 Feb 2011

Prime Healthcare Services alleges extortion campaign by SEIU

Prime Healthcare Services (PHS), the largest for-profit hospital system in California and the only for-profit system among Thomson Reuters' Top 10 Health Systems in 2009, announced today that it has been the victim of an extortion campaign by the Service Employees International Union – United Healthcare Workers West (SEIU) over the past year.

1 Feb 2011

IFT announces support for the 2010 Dietary Guidelines for Americans

The Institute of Food Technologists (IFT) today announced its support for the 2010 Dietary Guidelines for Americans (DGAs) as a landmark opportunity to ensure that Americans focus on healthier food choices and increased physical activity.

1 Feb 2011

Older Americans treated in Michigan ICUs see vast decrease in likelihood of dying: New study

Older Americans who were treated in Michigan intensive care units saw larger decreases in their likelihood of dying while hospitalized than similar ICU patients in other Midwestern hospitals, according to a new study evaluating an innovative quality improvement initiative funded by HHS' Agency for Healthcare Research and Quality.

1 Feb 2011

HighRes Biosolutions to build High-Throughput Laboratory Network for LANL-UCLA

A compact, self-contained, automated system for surveillance and screening of potential pandemic strains of influenza and other deadly infectious diseases is a step closer to reality, thanks to an agreement between Los Alamos National Laboratory, the University of California Los Angeles School of Public Health, and HighRes Biosolutions of Boston, Massachussets.

1 Feb 2011

IASLC publishes new international multidisciplinary classification for lung adenocarcinoma

Three of the world's top lung associations have published a new international multidisciplinary classification of lung adenocarcinoma, the first revision to the classification in six years.

1 Feb 2011

Current prevention efforts delay but do not prevent HCV among injection drug users

A recent 20-year study of injection drug users (IDUs) in Baltimore found a significant decline in new cases of HIV infection but only a slight decline in new cases of hepatitis C virus (HCV) infection. The findings suggest that efforts to curb blood-borne transmission of these viral infections have had success but must be expanded against the highly transmissible HCV.

1 Feb 2011

Brain scans can predict smokers' behavior change: New study

Brain scans showing neural reactions to pro-health messages can predict if you'll keep that resolution to quit smoking more accurately than you yourself can. That's according to a new study forthcoming in Health Psychology, a peer-reviewed journal.

1 Feb 2011

Public Health News and Research

Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

FDA disallows obesity drug Contrave pending further large-scale testing

Four-gene/protein signature more accurately predicts metastatic prostate cancer

Researchers discover potential vaccine capable of reducing H. pylori colonization

Bill Gates' annual letter calls for focus on eradicating polio, governments to sustain foreign aid

New research: Antioxidants in pecans may prevent development of various diseases

Economists suggest new approach to monitor nutrition, child mortality in developing countries

Roundup: Medicaid worries in Texas, Ill., Pa.; California insurance exchanges; Kansas controversy on health law

New Spanish version of ASPIRE for Hispanic teens

Surge of mosquito borne disease in South Australia following wet weather

Scientists test new dry powder measles vaccine that can be inhaled

Scientists successfully crystallise key norovirus enzyme

Elsevier announces publication of two position statements from EMAS in Maturitas journal

Prime Healthcare Services alleges extortion campaign by SEIU

IFT announces support for the 2010 Dietary Guidelines for Americans

Older Americans treated in Michigan ICUs see vast decrease in likelihood of dying: New study

HighRes Biosolutions to build High-Throughput Laboratory Network for LANL-UCLA

IASLC publishes new international multidisciplinary classification for lung adenocarcinoma

Current prevention efforts delay but do not prevent HCV among injection drug users

Brain scans can predict smokers' behavior change: New study

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