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Researchers identify key transcription factor linked with treatment-resistant prostate cancer

Prostate cancer is one of the most common forms of cancer in men and the leading cause of cancer deaths in white, African-American and Hispanic men, according to the Centers for Disease Control. Current treatment of prostate cancer targets androgens, hormones which promote the growth and spread of cancer cells.

20 Aug 2013

Endocrine Society, global partners to host international meeting for promoting endocrinology in India

Chevy Chase, MD-A new major collaborative partnership among international hormone health organizations will help promote endocrinology on the Indian sub-continent. The Endocrine Society has joined the Endocrine Society of India (ESI), the Society for Endocrinology in the United Kingdom and International Society of Endocrinology (ISE) to host the inaugural International Clinical Update program in Endocrinology (ICUE), February 1-2 in Hyderabad, India.

19 Aug 2013

High cholesterol level is more detrimental for middle aged men than women

High cholesterol levels are much more risky for middle-aged men than middle-aged women when it comes to having a first heart attack, a new study of more than 40,000 Norwegian men and women has shown.

17 Aug 2013

Researchers provide support for potential importance of vitamin D in pregnancy

Researchers at the MRC Lifecourse Epidemiology Unit, University of Southampton, have demonstrated that the degree to which a gene related to vitamin D action is switched on or off, when measured at birth, predicts bone density of the child at four years of age.

16 Aug 2013

Researchers identify key mechanism behind aggressive prostate cancer

A team of researchers from UC Davis, UC San Diego and other institutions has identified a key mechanism behind aggressive prostate cancer. Published on August 14 in Nature, the study shows that two long non-coding RNAs (PRNCR1 and PCGEM1) activate androgen receptors, circumventing androgen-deprivation therapy.

16 Aug 2013

Managing insulin levels through meal timing boosts ovulation in women with PCOS

Polycystic Ovarian Syndrome (PCOS), a common disorder that impairs fertility by impacting menstruation, ovulation, hormones, and more, is closely related to insulin levels. Women with the disorder are typically "insulin resistant" - their bodies produce an overabundance of insulin to deliver glucose from the blood into the muscles.

14 Aug 2013

Exo70 protein responsible for plasma membrane reshaping and cell movement

Both basic scientists and clinicians have an interest in how the cells of our body move. Cells must be mobile in order for organisms to grow, to heal, to transmit information internally, to mount immune responses and to conduct a host of other activities necessary for survival.

14 Aug 2013

Spikes in Tsimane testosterone responsible for performing physically demanding task

The everyday physical activities of an isolated group of forager-farmers in central Bolivia are providing valuable information about how industrialization and its associated modern amenities may impact health and wellness.

14 Aug 2013

Pregnant women with thyroid hormone deficiency are 4 times likelier to produce autistic children

Pregnant women who don't make nearly enough thyroid hormone are nearly 4 times likelier to produce autistic children than healthy women, report scientists from the Houston Methodist Neurological Institute and Erasmus Medical Centre in an upcoming Annals of Neurology (online today).

14 Aug 2013

Doctor offers tips on how to talk with your tween about puberty

Some parents may shy away from talking to their daughters about puberty, but Loyola University Health System obstetrician and gynecologist Akua Afriyie-Gray, MD, stresses the importance of sitting down with your tween when the time comes.

13 Aug 2013

Wayne State professor publishes new book that covers advances in nano cell biology

A Wayne State University School of Medicine professor has published a book that covers new advances in nano cell biology, nano medicine and imaging modalities.

12 Aug 2013

Specialized endocytocis play a crucial role in shaping cells themselves

The process cells use to 'swallow' up nutrients, hormones and other signals from their environment - called endocytosis - can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found.

12 Aug 2013

Tubingen researchers resolve how a plant steroid hormone makes plants grow

If one wants to better understand how plants grow, one must analyse the chemistry of life in its molecular detail. Michael Hothorn from the Friedrich-Miescher-Laboratory of the Max Planck Society in T-bingen and his team are doing just that. Their latest work now reveals that a plant membrane receptor requires a helper protein to sense a growth-promoting steroid hormone and to transduce this signal across the cell membrane.

9 Aug 2013

Autism affects men and women differently

Autism affects different parts of the brain in females with autism than males with autism, a new study reveals. The research is published today in the journal Brain as an open-access article.

9 Aug 2013

Mother's perceived social status predicts child's brain development, stress indicators

A mother's perceived social status predicts her child's brain development and stress indicators, finds a study at Boston Children's Hospital. While previous studies going back to the 1950s have linked objective socioeconomic factors—such as parental income or education—to child health, achievement and brain function, the new study is the first to link brain function to maternal self-perception.

9 Aug 2013

Immune function restored in spinal injured mice

In a new study, researchers at The Center for Brain and Spinal Cord Repair at The Ohio State University Wexner Medical Center show that is possible to restore immune function in spinal injured mice.

7 Aug 2013

Sleeping patterns of baby birds are similar to that of baby humans, find researchers

Researchers at the Max Planck Institute for Ornithology and the University of Lausanne have discovered that the sleeping patterns of baby birds are similar to that of baby mammals. What is more, the sleep of baby birds appears to change in the same way as it does in humans.

5 Aug 2013

Researchers show that JQ1 drug can block molecular pathway responsible for heart failure

Researchers from Case Western Reserve University School of Medicine and the Dana-Farber Cancer Institute have made a fundamental discovery relevant to the understanding and treatment of heart failure - a leading cause of death worldwide. The team discovered a new molecular pathway responsible for causing heart failure and showed that a first-in-class prototype drug, JQ1, blocks this pathway to protect the heart from damage.

2 Aug 2013

Male and female rats show different patterns of kidney gene expression throughout their lives

Male and female rats show different patterns of kidney gene expression throughout their lives, a study in the open access journal Biology of Sex Differences reveals. The finding could help explain some of the gender differences observed in human renal disease, and lead to improved biomarkers of kidney function.

31 Jul 2013

Takeda unbinds Phase 3 study of orteronel in patients with mCRPC that progressed post-chemotherapy

Takeda Pharmaceutical Company Limited ("Takeda") announced today that it has unblinded the ELM-PC 5 Phase 3 study (C21005) of orteronel plus prednisone compared to placebo plus prednisone in patients with metastatic, castration- resistant prostate cancer (mCRPC) that had progressed during or following chemotherapy based on the recommendation of the Independent Data Monitoring Committee (IDMC).

26 Jul 2013

Hormones News and Research

Researchers identify key transcription factor linked with treatment-resistant prostate cancer

Endocrine Society, global partners to host international meeting for promoting endocrinology in India

High cholesterol level is more detrimental for middle aged men than women

Researchers provide support for potential importance of vitamin D in pregnancy

Researchers identify key mechanism behind aggressive prostate cancer

Managing insulin levels through meal timing boosts ovulation in women with PCOS

Exo70 protein responsible for plasma membrane reshaping and cell movement

Spikes in Tsimane testosterone responsible for performing physically demanding task

Pregnant women with thyroid hormone deficiency are 4 times likelier to produce autistic children

Doctor offers tips on how to talk with your tween about puberty

Wayne State professor publishes new book that covers advances in nano cell biology

Specialized endocytocis play a crucial role in shaping cells themselves

Tubingen researchers resolve how a plant steroid hormone makes plants grow

Autism affects men and women differently

Mother's perceived social status predicts child's brain development, stress indicators

Immune function restored in spinal injured mice

Sleeping patterns of baby birds are similar to that of baby humans, find researchers

Researchers show that JQ1 drug can block molecular pathway responsible for heart failure

Male and female rats show different patterns of kidney gene expression throughout their lives

Takeda unbinds Phase 3 study of orteronel in patients with mCRPC that progressed post-chemotherapy

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