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Einstein Aging Study secures $32 million NIH grant to help address the rising tide of Alzheimer's disease

To help address the rising tide of Alzheimer's disease nationwide, researchers at Albert Einstein College of Medicine in collaboration with faculty at Pennsylvania State University and other institutions, have received a five-year, $32 million grant from the National Institutes of Health to support the ongoing Einstein Aging Study, which focuses on both normal aging and the special challenges of Alzheimer's disease, and other dementias. EAS was established at Einstein in 1980 and has been continuously funded by the NIH.

20 Apr 2022

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer’s

A little-studied enzyme has been found in high levels in healthy neurons, levels that scientists say decline with age and more dramatically with Alzheimer's, making adjusting the enzyme's level a potential treatment for both.

19 Apr 2022

Better understanding of hydrocephalus could lead to improved treatments

Hydrocephalus, or "water on the brain," occurs when the cerebral ventricles - four interconnected cavities of the brain that are filled with cerebrospinal fluid - become enlarged, but its cause is unknown in many cases.

18 Apr 2022

Researchers use computationally simple neuron model to simulate complex neuronal responses

The study shows the Izhikevich neuron model allows the simulation of both periodic and quasi-periodic responses in neurons at lower computational cost.

18 Apr 2022

The brain uses an alarm system to suppress unwanted memories

Forget what you saw: a brain region detects when you are about to think of an unwanted memory and alerts other regions to suppress it, according to research recently published in JNeurosci.

18 Apr 2022

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill Cornell Medicine investigators.

14 Apr 2022

Exercise maintains insulin and body mass index levels to help protect brain volume

Studies have shown that exercise helps protect brain cells. A new study looking at the mechanisms involved in this relationship suggests that the role exercise plays in maintaining insulin and body mass index levels may help protect brain volume and thus help stave off dementia.

14 Apr 2022

Social connections predict the brain structure of primates

What's the link between social life and brain structure? Researchers from the University of Pennsylvania, the Stem Cell and Brain Research Institute at Inserm, and elsewhere are now one step closer to understanding this connection for rhesus macaques.

13 Apr 2022

Prenatal exposure to maternal social disadvantage may affect infant brain volumes at birth

Poverty and crime can have devastating effects on a child's health. But a new study from researchers at Washington University School of Medicine in St. Louis suggests that some environmental factors influence the structure and function of young brains even before babies make their entrances into the world.

12 Apr 2022

Machine-learning approach predicts development of conduct disorder with high accuracy

Conduct disorder (CD) is a common yet complex psychiatric disorder featuring aggressive and destructive behavior.

12 Apr 2022

Bilingualism can slow down the course of age-related changes in the brain

Medical advances are causing a gradual increase in average life expectancy. However, this comes at a price, as the number of cases of dementia and other neurodegenerative diseases grows with age. Researchers from HSE University (Russia) and Northumbria University (UK) have found that bilingualism can slow down and mitigate the course of age-related changes in the human brain.

11 Apr 2022

New Russian-language protocol for fMRI enables preoperative mapping of language areas

Neurolinguists from HSE University, in collaboration with radiologists from the Pirogov National Medical and Surgical Centre, developed a Russian-language protocol for functional magnetic resonance imaging (fMRI) that makes it possible to map individual language areas before neurosurgical operations.

8 Apr 2022

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

New findings from the ongoing Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study suggest that certain rheumatoid arthritis drugs may lower incidence of Alzheimer's disease and related dementias in people with cardiovascular disease.

8 Apr 2022

Mutant mice with a human gene variant exhibits ADHD-like problems

Mutant mice are providing scientists with a new neurobiological framework to understand the brain changes observed in distractible humans who carry a common gene variant whose frequency has been associated with Attention Deficit Hyperactivity Disorder (ADHD).

7 Apr 2022

Axol Bioscience Raises £3.2 Million GBP (c. $4.2 million USD)

Axol Bioscience Ltd. today announced that it has raised £3.2 million GBP in the extension of its previous funding round, bringing the total raised to £7 million GBP.

From Axol Bioscience Ltd 7 Apr 2022

People with some types of epilepsy may have a lower quality of life, study suggests

A new study suggests that people with epilepsy associated with head injuries, especially the type not well controlled by medication, are more likely to have other health conditions like depression, post-traumatic stress disorder (PTSD), back pain and headache that may result in them reporting a lower quality of life.

6 Apr 2022

High-throughput screening assay could identify new prostate cancer drugs

A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer.

6 Apr 2022

Insights into the pathophysiology of NeuroCOVID

A new study describes the neurological features of COVID-19, both short- and long-term.

6 Apr 2022

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Critical Path Institute's Type 1 Diabetes Consortium (T1DC) today announced that the European Medicines Agency has issued a positive qualification opinion for pancreatic islet autoantibodies as enrichment biomarkers for type 1 diabetes (T1D) prevention trials.

5 Apr 2022

Difficult experiences in childhood influence vaccine resistance in adulthood

Curious about why some people have been so passionately, often angrily, opposed to vaccination against the COVID-19 virus, a team of researchers with access to rare and unusual insights into the childhood forces that shape our adult lives thought they'd try to find out.

5 Apr 2022

Neuroscience News and Research

Einstein Aging Study secures $32 million NIH grant to help address the rising tide of Alzheimer's disease

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer’s

Better understanding of hydrocephalus could lead to improved treatments

Researchers use computationally simple neuron model to simulate complex neuronal responses

The brain uses an alarm system to suppress unwanted memories

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Exercise maintains insulin and body mass index levels to help protect brain volume

Social connections predict the brain structure of primates

Prenatal exposure to maternal social disadvantage may affect infant brain volumes at birth

Machine-learning approach predicts development of conduct disorder with high accuracy

Bilingualism can slow down the course of age-related changes in the brain

New Russian-language protocol for fMRI enables preoperative mapping of language areas

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

Mutant mice with a human gene variant exhibits ADHD-like problems

Axol Bioscience Raises £3.2 Million GBP (c. $4.2 million USD)

People with some types of epilepsy may have a lower quality of life, study suggests

High-throughput screening assay could identify new prostate cancer drugs

Insights into the pathophysiology of NeuroCOVID

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Difficult experiences in childhood influence vaccine resistance in adulthood

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