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Researchers discover unique process of brain cell death in MS

Researchers at the University of Alberta have discovered a unique process of brain cell death that affects the cells that are most vulnerable in multiple sclerosis.

13 Jun 2018

Study uncovers new molecular mechanisms of Parkinson's disease

Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson's disease.

12 Jun 2018

Researchers discover genomic characteristics that define testicular germ cell cancer

Testicular germ cell cancer, a disease that is rare but growing in incidence in men in the United States, is considered to be among the most curable of solid tumors. Now researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and a consortium of institutions have discovered the genetic and genomic characteristics that define the disease.

12 Jun 2018

UNC study provides insight into mechanism of CHD4-related heart defects

Heart defects are the most common type of birth defect, and can be caused by mutations in the gene CHD4. Researchers at the UNC School of Medicine have now revealed key molecular details of how CHD4 mutations lead to heart defects.

12 Jun 2018

Study shows how amyloid aggregates alter brain cells in Alzheimer’s disease

A new study has revealed the mechanism through which amyloid peptide aggregates alter brain cells to cause the harmful effects seen in Alzheimer’s disease.

12 Jun 2018

AbCellera and Denali collaborate to discover new antibodies to fight neurodegenerative diseases

AbCellera Biologics Inc. today announced the successful completion of the first phase of its collaboration with Denali Therapeutics Inc.

12 Jun 2018

Scientists discover first genetic marker for bone tumor

The first genetic marker for the bone tumor, osteoblastoma, has been discovered by scientists at the Wellcome Sanger Institute and their collaborators.

12 Jun 2018

Researchers develop spider silk microcapsules that can deliver vaccine directly to immune cells

To fight cancer, researchers increasingly use vaccines that stimulate the immune system to identify and destroy tumor cells.

12 Jun 2018

Researchers discover new method to predict chance of cancer treatment success

Doctors are increasingly fighting cancer by stimulating patients' immune systems. SNSF-supported researchers have now discovered a method for predicting the likelihood of treatment success.

12 Jun 2018

Cureworks collaborative aims to accelerate development of immunotherapies for pediatric cancer

Seattle Children's, with participating members Children's National Health System, BC Children's Hospital and Children's Hospital Los Angeles, has launched CureWorks, an international collaborative of leading academic children's hospitals determined to accelerate the development of immunotherapy treatments for childhood cancer.

12 Jun 2018

IU researchers observe bacteria's 'DNA uptake' process

Indiana University scientists have made the first direct observation of a key step in the process that bacteria use to rapidly evolve new traits, including antibiotic resistance.

12 Jun 2018

Teens and young adults with type 1 diabetes often experience stigma

Michael Wright was your average high school student, juggling the responsibilities of school and friends while taking the first steps towards finding his first real job.

12 Jun 2018

Customising T-cells for cancer immunotherapy

T-cell immunotherapy is revolutionizing cancer treatments. CD8+ T cells are modified to recognize tumor-specific antigens and induce an immune response.

12 Jun 2018

Hydrogel releases nerve-protecting agent to restore breathing in animal models

One of the most severe outcomes of spinal cord injury from car accidents, sports impacts, or other neck trauma, is losing the ability to control breathing, with patients often requiring artificial ventilation for the rest of their lives.

12 Jun 2018

Scientists find novel tactic with potential for fighting medulloblastoma

Scientists have a new tactic with potential for fighting medulloblastoma, the most common and most aggressive form of brain tumor in children. The results are scheduled for publication in Cancer Cell.

12 Jun 2018

Penn research team identifies novel therapeutic target for heart disease

Changes in cellular struts called microtubules (MT) can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure, found researchers from the Perelman School of Medicine at the University of Pennsylvania.

12 Jun 2018

Scientists pinpoint potential treatment target for pediatric liver cancer

A protein in the cell nucleus already targeted therapeutically for several types of cancer has now been linked to an aggressive form of pediatric liver cancer called hepatoblastoma (HBL), according to a study published in the Nature journal Communications Biology.

11 Jun 2018

Synthetic gene reveals potential therapeutic target for rare, inherited disease

DNA Repair is essential for a healthy organism. In every day of our lives, tens of thousands of damages occur in the genetic material of our cells. Hence, it is not surprising that a broad variety of repair mechanisms developed in the course of evolution that enables cells to quickly react and patch up the affected DNA strands.

11 Jun 2018

CRISPR-Cas9 technique may raise cancer risk

Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published in Nature Medicine.

11 Jun 2018

Study shows positive vascular effects of mango intake in postmenopausal women

A new study conducted at the University of California, Davis found that two cups of mangos a day had beneficial effects on systolic blood pressure among healthy postmenopausal women.

11 Jun 2018