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Understanding molecular mechanisms underlying human aging

Researchers have found differences between normal and pathologic peptidomic changes that may lead to an improved understanding of molecular mechanisms underlying aging. Proteome analysis in combination with therapy may influence pathologic aging.

22 Oct 2015

Research provides leads for new strategies to develop HIV vaccine

Recent research has yielded new information about immune responses associated with--and potentially responsible for--protection from HIV infection, providing leads for new strategies to develop an HIV vaccine.

22 Oct 2015

Researchers use cutting edge genomic methods to explain protective effects of malaria vaccine candidate

An international team led by researchers from the Broad Institute of MIT and Harvard, the Harvard T.H. Chan School of Public Health, and Fred Hutchinson Cancer Research Center have used cutting edge genomic methods to uncover key biological insights that help explain the protective effects of the world's most advanced malaria vaccine candidate, RTS,S/AS01 (RTS,S).

22 Oct 2015

Scientists map out the brain circuitry critical for filtering out distractions

In a study of mice, scientists discovered that a brain region called the thalamus may be critical for filtering out distractions. The study, published in Nature and partially funded by the National Institutes of Health, paves the way to understanding how defects in the thalamus might underlie symptoms seen in patients with autism, attention deficit hyperactivity disorder (ADHD), and schizophrenia.

22 Oct 2015

Lifestyle choices, occupational factors may contribute to crashes among truck drivers

Truck drivers who are frequently fatigued after work, use cell phones while driving, or have an elevated pulse pressure - a potential predictor of cardiovascular disease - may be at increased risk for getting into truck accidents, according to a study by the Rocky Mountain Center for Occupational and Environmental Health at the University of Utah School of Medicine and published in the Journal of Occupational and Environmental Medicine.

22 Oct 2015

New test may help predict spread of breast cancer to the brain

Women with particularly aggressive forms of breast cancer could be identified by a test that predicts whether the disease is likely to spread to the brain.

22 Oct 2015

New study from TSRI and Salk points to cause of debilitating nerve disease

Scientists at The Scripps Research Institute (TSRI) and the Salk Institute for Biological Studies have discovered how a mutant protein triggers nerve damage in a subtype of Charcot-Marie-Tooth (CMT) diseases, a group of currently untreatable conditions that cause loss of function in a person’s hands and feet.

22 Oct 2015

Two-stage CDS system reduces risk of adverse outcomes for sepsis patients

Sepsis is an inflammatory response to infection that's known to develop in hospital settings and can turn deadly when it's not discovered early on. In a new study, a hospital surveillance program focusing on reducing the risks of sepsis, known as the two-stage Clinical Decision Support (CDS) system, was found to reduce the risk of adverse outcomes, such as death and hospice discharge for sepsis patients, by 30% over the course of one year.

22 Oct 2015

Scientists reveal link between depression and paraventricular thalamus

Scientists from the RIKEN Brain Science Institute have shown that a mouse strain with a mutation that leads to dysfunction of mitochondria--the "powerhouses" that provide energy to cells--spontaneously undergo periodic episodes of depression-like behavior that resemble those in human. Through this research, published in Molecular Psychiatry, the scientists uncovered a link between depression and the paraventricular thalamus, a region of the brain not previously tied to depression.

20 Oct 2015

Research: Heavy drinkers, illegal drug users downplay their consumption levels compared to others

Heavy drinkers and users of illegal drugs downplay their relative levels of consumption, when comparing themselves to others, reveals research by the London School of Economics and Political Science and South London and Maudsley NHS Foundation Trust.

20 Oct 2015

Study shows how synapses organization is controlled

Our ability to learn, move, and sense our world comes from the neurons in our brain. This information moves through our brain between neurons that are linked together by tens of trillions of tiny structures called synapses.

20 Oct 2015

Biomedical scientists discover mechanism by which secreted proteins age

Physiological processes in the body are in large part determined by the composition of secreted proteins found in the circulatory systems, including the blood. Each of the hundreds of proteins in the blood has a specific life span that determines its unique range of abundance. In fact, measurements of their quantities and activities contribute to many clinical diagnoses.

20 Oct 2015

Low levels of stem cell factor associated with increased risk of cardiovascular disease

New research indicates that low levels of a growth factor called stem cell factor (SCF)--which is thought to be important for blood vessel repair--are linked with an increased risk of cardiovascular disease.

20 Oct 2015

Use of hearing aids may help safeguard memory and thinking skills in older adults

Hearing loss is linked with accelerated cognitive decline in older adults, but the use of hearing aids may help safeguard seniors' memory and thinking skills.

20 Oct 2015

Psychological interventions may improve sexual health of men with sleep apnea

Burdens related to poor sleep may put men with sleep apnea at increased risk of erectile dysfunction. In a study of 713 male patients who visited Seoul National University Hospital for snoring and/or daytime sleepiness from 2006 to 2014, depressive symptoms and a low quality of life due to sleep problems were clearly linked to erectile dysfunction.

20 Oct 2015

New genetic discovery could lead to better treatment for X-linked diseases

Think back to middle school biology class, when you learned that boys have an X and a Y chromosome inside each cell, and girls have two X's.

20 Oct 2015

Sequenom enters into clinical collaboration with CU School of Medicine

Sequenom, Inc., a life sciences company committed to enabling healthier lives through the development of innovative products and services, today announced that it has entered into a clinical collaboration with the University of Colorado Denver, School of Medicine.

19 Oct 2015

Study could lead to better understanding of metabolic processes behind type 2 diabetes

Scientists in Sweden have discovered that human intestinal flora regulates the levels of the body's main antioxidant, glutathione, which fights a host of diseases. The findings could lead to new probiotic-delivering foods, and a better understanding of the metabolic processes behind diseases such as type 2 diabetes.

19 Oct 2015

Premature babies face increased risk of mental illness due to weakened connections in brain networks

Babies born prematurely face an increased risk of neurological and psychiatric problems that may be due to weakened connections in brain networks linked to attention, communication and the processing of emotions, new research shows.

19 Oct 2015

Discovery may provide noninvasive approach to assessing toxic effects of anesthetic agents in children

Could looking at the eyes provide a new way of studying how anesthesia affects the developing brain? The retinas of immature mice exposed to one widely used general anesthetic show evidence of "programmed cell death," or apoptosis, reports a study in Anesthesia & Analgesia.

19 Oct 2015

X linked News and Research

Understanding molecular mechanisms underlying human aging

Research provides leads for new strategies to develop HIV vaccine

Researchers use cutting edge genomic methods to explain protective effects of malaria vaccine candidate

Scientists map out the brain circuitry critical for filtering out distractions

Lifestyle choices, occupational factors may contribute to crashes among truck drivers

New test may help predict spread of breast cancer to the brain

New study from TSRI and Salk points to cause of debilitating nerve disease

Two-stage CDS system reduces risk of adverse outcomes for sepsis patients

Scientists reveal link between depression and paraventricular thalamus

Research: Heavy drinkers, illegal drug users downplay their consumption levels compared to others

Study shows how synapses organization is controlled

Biomedical scientists discover mechanism by which secreted proteins age

Low levels of stem cell factor associated with increased risk of cardiovascular disease

Use of hearing aids may help safeguard memory and thinking skills in older adults

Psychological interventions may improve sexual health of men with sleep apnea

New genetic discovery could lead to better treatment for X-linked diseases

Sequenom enters into clinical collaboration with CU School of Medicine

Study could lead to better understanding of metabolic processes behind type 2 diabetes

Premature babies face increased risk of mental illness due to weakened connections in brain networks

Discovery may provide noninvasive approach to assessing toxic effects of anesthetic agents in children

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