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Pomalidomide safe, effective and extends overall survival for patients with multiple myeloma

Researchers at Moffitt Cancer Center and colleagues have investigated the safety, efficacy and the maximum tolerated dose of pomalidomide for patients with multiple myeloma who have disease relapsed after treatments with other drugs, such as bortezomib and lenalidomide.

24 Jan 2013

Institute of Bioengineering and Nanotechnology, IBM reveal new antimicrobial hydrogel

Researchers from IBM and the Institute of Bioengineering and Nanotechnology revealed today an antimicrobial hydrogel that can break through diseased biofilms and completely eradicate drug-resistant bacteria upon contact.

24 Jan 2013

Study may help predict which multiple myeloma patients will respond better to certain treatments

A study led by Robert G. Hawley, Ph.D., professor and chair of the department of anatomy and regenerative biology at the George Washington University (GW) School of Medicine and Health Sciences (SMHS), may help predict which patients with multiple myeloma will respond better to certain treatments.

24 Jan 2013

World Cancer Day to focus on awareness and prevention, importance of research

Cancer takes the lives of some 7.6 million people worldwide each year, according to the World Health Organization. And while the upcoming World Cancer Day will focus on a global message of cancer awareness and prevention, the importance of cancer research also will resonate.

23 Jan 2013

KLF6-SV1 gene variant drives the spread of breast cancer

A team of researchers led by Goutham Narla, MD, PhD, at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, and collaborators at the Mount Sinai School of Medicine and Erasmus Medical Center, have discovered a gene variant that drives the spread of breast cancer.

23 Jan 2013

Study identifies how astrocytes regulate a neurotransmitter involved in sleep

Neuroscience researchers from Tufts University have found that our star-shaped brain cells, called astrocytes, may be responsible for the rapid improvement in mood in depressed patients after acute sleep deprivation. This in vivo study, published in the current issue of Translational Psychiatry, identified how astrocytes regulate a neurotransmitter involved in sleep.

23 Jan 2013

Salk Institute to establish Helmsley Center for Genomic Medicine

The Salk Institute for Biological Studies has received a $42 million gift-the largest in the Institute's history-to establish the Helmsley Center for Genomic Medicine (HCGM), a research center dedicated to decoding the common genetic factors underlying many complex chronic human diseases.

23 Jan 2013

Novartis receives FDA approval for Exjade to treat chronic iron overload in NTDT patients

The U.S. Food and Drug Administration today expanded the approved use of Exjade (deferasirox) to treat patients ages 10 years and older who have chronic iron overload resulting from a genetic blood disorder called non-transfusion-dependent thalassemia (NTDT).

23 Jan 2013

Taking antiepileptic drug valproate during pregnancy affects the IQ of children

Research published in The Lancet Neurology shows that taking the antiepileptic drug valproate during pregnancy affects the IQ of children up to the age of six.

23 Jan 2013

Amgen drug gets boost in fiscal cliff legislation

Just two weeks after pleading guilty in a major federal fraud case, Amgen, the world's largest biotechnology firm, scored a largely unnoticed coup on Capitol Hill: Lawmakers inserted a paragraph into the "fiscal cliff" bill that did not mention the company by name but strongly favored one of its drugs.

23 Jan 2013

SMO and AKT1 mutations appear to drive about 15% of meningiomas

Large-scale genomic sequencing has revealed two DNA mutations that appear to drive about 15 percent of brain tumors known as meningiomas, a finding that could lead to the first effective drug treatments for the tumors, report scientists from Dana-Farber Cancer Institute and the Broad Institute.

23 Jan 2013

Health law's new spending offers tempting target for lawmakers in search of savings

The overhaul includes $1.7 trillion in new spending over the next decade -- which is being eyed by members of Congress for various reasons. Meanwhile, the Los Angeles Times reports on a mental health coverage gap in the health law's effort to expand access to health care, and The Washington Post reports on how employer challenges to the law are taking shape.

23 Jan 2013

Study details exactly how Her2 gene promotes progression and spread of breast cancer cells

Research led by Dr. Suresh Alahari, the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans and its Stanley S. Scott Cancer Center, details exactly how the Her2 cancer gene promotes the progression and spread of breast cancer cells.

23 Jan 2013

Novel way to engineer specialized immune cells targeted by the AIDS virus

Researchers at the Stanford University School of Medicine have found a novel way to engineer key cells of the immune system so they remain resistant to infection with HIV, the virus that causes AIDS.

23 Jan 2013

Studies identify cellular pathways involved in governing day-night pattern of circadian rhythms

UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms - also known as the body clock - modify energy metabolism and also have identified novel compounds that control this action. The findings point to potential treatments for disorders triggered by circadian rhythm dysfunction, ranging from insomnia and obesity to diabetes and cancer.

23 Jan 2013

UB scientists propose first genomic explanation for schizophrenia

New University at Buffalo research demonstrates how defects in an important neurological pathway in early development may be responsible for the onset of schizophrenia later in life.

23 Jan 2013

SLU team discovers molecular pathway that contributes to triple-negative breast cancer

In research published in the Jan. 17 issue of The Journal of Cell Biology, a team led by Susana Gonzalo, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, has discovered a molecular pathway that contributes to triple-negative breast cancer, an often deadly and treatment resistant form of cancer that tends to strike younger women.

23 Jan 2013

Amyloid clue to Parkinson’s dementia

Study findings link amyloid β burden to future cognitive decline in patients with Parkinson’s disease.

22 Jan 2013

Dutasteride decreases risk of biopsy detectable prostate cancer by 22.8%

The four-year REDUCE (REduction by DUtasteride of prostate Cancer Events) clinical study evaluated prostate cancer risk reduction in men taking dutasteride, a 5-alpha-reductase inhibitor (5ARI) typically used to treat enlarged prostate.

22 Jan 2013

FDA approves Ampio’s IND for Optina for treatment of diabetic macular edema

Ampio Pharmaceuticals, Inc. announced today that the FDA has accepted the Company's IND for Optina™ for the treatment of diabetic macular edema (DME). Ampio plans to commence enrollment in a clinical trial in the first quarter of 2013. The FDA granted Optina™ 505(b)(2) status in July, 2012. Drugs designated under this pathway can be approved on a single trial.

22 Jan 2013

Drugs News and Research

Pomalidomide safe, effective and extends overall survival for patients with multiple myeloma

Institute of Bioengineering and Nanotechnology, IBM reveal new antimicrobial hydrogel

Study may help predict which multiple myeloma patients will respond better to certain treatments

World Cancer Day to focus on awareness and prevention, importance of research

KLF6-SV1 gene variant drives the spread of breast cancer

Study identifies how astrocytes regulate a neurotransmitter involved in sleep

Salk Institute to establish Helmsley Center for Genomic Medicine

Novartis receives FDA approval for Exjade to treat chronic iron overload in NTDT patients

Taking antiepileptic drug valproate during pregnancy affects the IQ of children

Amgen drug gets boost in fiscal cliff legislation

SMO and AKT1 mutations appear to drive about 15% of meningiomas

Health law's new spending offers tempting target for lawmakers in search of savings

Study details exactly how Her2 gene promotes progression and spread of breast cancer cells

Novel way to engineer specialized immune cells targeted by the AIDS virus

Studies identify cellular pathways involved in governing day-night pattern of circadian rhythms

UB scientists propose first genomic explanation for schizophrenia

SLU team discovers molecular pathway that contributes to triple-negative breast cancer

Amyloid clue to Parkinson’s dementia

Dutasteride decreases risk of biopsy detectable prostate cancer by 22.8%

FDA approves Ampio’s IND for Optina for treatment of diabetic macular edema

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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