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Mitsubishi Tanabe Pharma in-licenses CETP inhibitor to Dezima Pharma

Dezima Pharma ('Dezima'), the biotechnology company developing innovative drugs in the field of dyslipidemia, announced today the in-licensing of a cholesteryl ester transfer protein (CETP) inhibitor DEZ-001 (formerly TA-8995) from Mitsubishi Tanabe Pharma Corporation (MTPC). Terms of the deal were not disclosed.

22 Jan 2013

Study reveals ugly cholesterol is the direct cause of ischaemic heart disease

The risk of ischaemic heart disease - a disease affecting some 150,000 Danes - is three times higher in persons with high levels of the so-called 'ugly' cholesterol. This is the finding of a new study of 73,000 Danes, which is shedding light on a long debate on this topic. The results have just been published in the Journal of the American College of Cardiology.

22 Jan 2013

Studies suggest a new approach to treating HIV

A team of researchers based at Johns Hopkins has decoded a system that makes certain types of immune cells impervious to HIV infection.

22 Jan 2013

New DNA chip could improve diagnosis and therapeutics of ADHD

Attention Deficit Hyperactivity Disorder (ADHD) is the most common childhood neuropsychiatric disorder. Yet there is currently no tool that will confirm the diagnosis of ADHD. In her thesis entitled "Development of a genotyping system to be applied in Attention Deficit Hyperactivity Disorder and its Pharmacogenetics".

22 Jan 2013

Biophysical Society Annual Meeting to highlight innovations in medicine, physics, and more

Honeybee silk-inspired materials; a deconstruction of the Ebola virus; how microbes evolve resistance to antibiotics; and a possible connection between Alzheimer's disease and type II diabetes are just some of the intriguing topics that will be presented at the 57th Annual Meeting of the Biophysical Society (BPS).

22 Jan 2013

BRCA1-deficient cancer cells take advantage of DNA repair mechanism

Cancer cells are resourceful survivors with plenty of tricks for staying alive. Researchers have uncovered one of these stratagems, showing how cells lacking the tumor suppressor BRCA1 can resume one form of DNA repair, sparing themselves from stagnation or death. The study appears in the January 21st issue of The Journal of Cell Biology.

22 Jan 2013

Golden nanoparticle starves cancer cell to death

How do you annihilate lymphoma without using any drugs? Starve it to death by depriving it of what appears to be a favorite food: HDL cholesterol.

21 Jan 2013

Itch-specific nerve cells: an interview with Associate Professor Xinzhong Dong

Itch was actually defined by a German physician more than 350 years ago. His name was Samuel Hafenreffer. He defined itch as an unpleasant sensation that makes people want to scratch. You probably think this is a very simple definition but itch is really a very complex sensory modality.

21 Jan 2013

Scientists identify new mechanism that turns CD4 helper T lymphocytes into killer cells

A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against viruses, cancerous tumors and other damaged or infected cells.

21 Jan 2013

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.

21 Jan 2013

New method may help predict response to chemotherapy for bowel cancer

Scientists at the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital have developed a new method of predicting which patients with bowel (colorectal) cancer will respond effectively to chemotherapy. The results of this study are published in the current issue of the prestigious Cancer Research journal.

19 Jan 2013

UC Davis professor receives supplemental funds from Parent Project Muscular Dystrophy

Parent Project Muscular Dystrophy (PPMD) has awarded Dr. Craig McDonald of the University of California, Davis (UC Davis) $175,000 in supplemental funds to expand his ongoing study through the 20 CINRG (Cooperative International Neuromuscular Research Group) centers to better understand the progression of Duchenne muscular dystrophy (Duchenne) and determine the impact of the Duchenne standards of care established by the Centers for Disease Control (CDC).

19 Jan 2013

Calcium receptor – potential drug target for sleeping sickness

While its common name may make it sound almost whimsical, sleeping sickness, or African trypanosomiasis, is in reality a potentially fatal parasitic infection that has ravaged populations in sub-Saharan Africa for decades, and it continues to infect thousands of people every year.

19 Jan 2013

Review underscores safety of federal childhood immunization schedule

A review of the available evidence underscores the safety of the federal childhood immunization schedule, according to a report released today by the Institute of Medicine. University of Michigan population ecologist Pejman Rohani served on the 13-person committee that wrote the report.

19 Jan 2013

Survey finds shortage of TB medicines in U.S.; Consequences similar to lack of access in developing countries, advocate says

"More than 80 percent of health departments in the United States that treat tuberculosis [TB] resistant to standard treatment have trouble obtaining the drugs they need to cure the disease, according to a national survey released on Thursday," Reuters reports.

18 Jan 2013

Research provides unique insight into the often misunderstood world of addiction

People who take cocaine over many years without becoming addicted have a brain structure which is significantly different from those individuals who developed cocaine-dependence, researchers have discovered.

18 Jan 2013

Reports examine global NTD response one year after London declaration

Two reports released Wednesday provide an update on the global response against neglected tropical diseases (NTDs) a year after leaders of some of the world's largest pharmaceutical companies met in London and agreed to fight the diseases, Guardian health editor Sarah Boseley reports in her "Global Health Blog."

18 Jan 2013

Macular pigment screening: an interview with Jaquie Finn, Product Line Manager at Elektron Technology

AMD is the leading cause of vision loss in anyone over 50 and globally in 2010 it was estimated to cost $340 billion to treat AMD. The costs are set to spiral over the next 20 years and really over burden the healthcare system unless people start to take preventative action.

18 Jan 2013

Medications often prescribed for PAH could affect heart health of treated patients

A research team with the Faculty of Medicine & Dentistry at the University of Alberta reported findings that significantly improve understanding of how widely used drugs in Pulmonary Arterial Hypertension (PAH) affect the heart health of treated patients.

18 Jan 2013

Blog features two posts on new NTD publications

The Global Network for Neglected Tropical Diseases' (NTDs) "End the Neglect" blog features two posts discussing the first anniversary of the London Declaration and two recently released reports on progress against NTDs.

18 Jan 2013

Drugs News and Research

Mitsubishi Tanabe Pharma in-licenses CETP inhibitor to Dezima Pharma

Study reveals ugly cholesterol is the direct cause of ischaemic heart disease

Studies suggest a new approach to treating HIV

New DNA chip could improve diagnosis and therapeutics of ADHD

Biophysical Society Annual Meeting to highlight innovations in medicine, physics, and more

BRCA1-deficient cancer cells take advantage of DNA repair mechanism

Golden nanoparticle starves cancer cell to death

Itch-specific nerve cells: an interview with Associate Professor Xinzhong Dong

Scientists identify new mechanism that turns CD4 helper T lymphocytes into killer cells

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

New method may help predict response to chemotherapy for bowel cancer

UC Davis professor receives supplemental funds from Parent Project Muscular Dystrophy

Calcium receptor – potential drug target for sleeping sickness

Review underscores safety of federal childhood immunization schedule

Survey finds shortage of TB medicines in U.S.; Consequences similar to lack of access in developing countries, advocate says

Research provides unique insight into the often misunderstood world of addiction

Reports examine global NTD response one year after London declaration

Macular pigment screening: an interview with Jaquie Finn, Product Line Manager at Elektron Technology

Medications often prescribed for PAH could affect heart health of treated patients

Blog features two posts on new NTD publications

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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