Age Related Macular Degeneration News and Research

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RXi Pharmaceuticals begins Phase 1/2 clinical trial in ophthalmology

RXi Pharmaceuticals Corporation a biotechnology company focused on discovering and developing innovative therapies primarily in the areas of dermatology and ophthalmology today announced the initiation of a Phase 1/2 clinical trial in ophthalmology. The clinical study RXI-109-1501 will evaluate the safety and clinical activity of RXI-109 to prevent the progression of retinal scarring, a harmful component of numerous retinal diseases.

5 Nov 2015

Good news for patients suffering from dry age-related macular degeneration

Scientists have good news for patients who suffer from currently untreatable dry age-related macular degeneration (dry AMD). In a new study, researchers identified a potential target for future therapies to slow the progression of the blinding condition. Published in Investigative Ophthalmology & Visual Science, the findings indicate that treatments currently used for other conditions could also work for dry AMD.

3 Nov 2015

Franziska Michor named recipient of NYSCF - Robertson Stem Cell Prize

The New York Stem Cell Foundation announced today that Franziska Michor, PhD, is the 2015 recipient of the NYSCF - Robertson Stem Cell Prize for her work pioneering new approaches to study the growth, spread, and treatment of cancer. Her laboratory fuses her passions in mathematics, molecular biology and patient care to investigate how cancers form and progress.

29 Oct 2015

NYSCF conference to focus on translational stem cell and neuroscience research

The New York Stem Cell Foundation 10th Annual Translational Stem Cell Research Conference convenes global leaders in translational stem cell and neuroscience research to present their latest work towards new treatments and cures for the most devastating diseases and injuries currently facing the world.

26 Oct 2015

NAM announces election of three new members from UC San Diego School of Medicine

The National Academy of Medicine announced today the election of three new members from University of California, San Diego School of Medicine: Napoleone Ferrara, MD; Christopher K. Glass, MD, PhD; and Roberto Malinow, MD, PhD. Election to NAM is considered among the highest honors in the fields of health and medicine.

20 Oct 2015

Allergan completes acquisition of AqueSys

Allergan plc, a leading global pharmaceutical company, today announced that it has successfully completed the acquisition of AqueSys, Inc. a clinical-stage medical device company focused on developing ocular implants that reduce intraocular pressure (IOP) associated with glaucoma.

19 Oct 2015

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

An international research team led by scientists at the University of New Mexico Cancer Center discovered and developed a novel ligand peptide-mimic that inhibits abnormal overgrowth of blood vessels in retinal diseases and tumors. The discovery could lead to new drugs that keep cancers from growing. The team published a paper in the journal Science Translational Medicine.

15 Oct 2015

Lonza, Benitec partner to develop scalable manufacturing process for AAV-based viral gene therapies

Lonza Houston, Inc., a global leader in biological, cell and viral gene therapy manufacturing, and Benitec Biopharma, a clinical stage biotechnology company commercializing a patented gene-silencing technology, DNA-directed RNA interference (ddRNAi), today announced that they have entered into a Manufacturing Services Agreement to develop a scalable manufacturing process for Benitec's ddRNAi-based, Adeno-Associated Virus (AAV)-delivered products intended for therapeutic use in humans.

7 Oct 2015

Envisia's ENV515 (travoprost XR) meets primary efficacy endpoint in phase 2a glaucoma trial

Envisia Therapeutics, a clinical-stage biotechnology company focused on the development of novel extended-release therapies in ophthalmology, today reported results from its first clinical trial of the Company's lead product candidate, ENV515 (travoprost XR).

6 Oct 2015

Oraya therapy is effective in maintaining vision with reduced injections for wet AMD patients

The results show that Oraya Therapy is effective in maintaining vision with reduced injections for patients at different stages of their disease—from chronic patients in discontinuous treatment to treatment-naive patients with new diagnosis—and following different treatment pathways.

1 Oct 2015

Adults with AMD are accurate, but slower in performing touch screen tasks

Older adults with central vision loss caused by age-related macular degeneration (AMD) have no problem with accuracy in performing touch screen tasks, according to a study in the October issue of Optometry and Vision Science, official journal of the American Academy of Optometry.

24 Sep 2015

Matricellular proteins may be key therapeutic targets for common ocular disorders

A special issue of Journal of Ocular Pharmacology and Therapeutics highlights the latest research on matricellular proteins, which play a critical role in inflammation and blood vessel formation in the eye and therefore making them key targets for new therapies to treat common ocular disorders such as glaucoma, dry eye disease, and age-related macular degeneration (AMD).

23 Sep 2015

Researchers receive NIH grants to find genomic regions containing variants that affect disease risk

Six new grants from the National Institutes of Health will support researchers to develop new computational approaches for searching among millions of genomic variants to find those that make a difference in disease susceptibility or in other traits.

23 Sep 2015

UK’s GPs, optometrists confirm link between smoking and loss of vision

Smokey eyes are regarded as sexy, sultry and stunning. But nothing could be further from the truth, according to new research unveiled this National Eye Health Week.

18 Sep 2015

Benitec Biopharma initiates new site for ongoing Phase 1/2a TT-034 trial for hepatitis C

Benitec Biopharma Limited, a clinical-stage biotechnology company developing innovative therapeutics based on its gene-silencing technology, DNA-directed RNA interference (ddRNAi), is pleased to announce it has initiated a new site for its ongoing Phase 1/2a TT-034 trial at the Methodist Health System Clinical Research Institute in Dallas, Texas.

16 Sep 2015

AMD Alliance hosts webinar to promote awareness and knowledge about macular disease

14 – 20 September marks global AMD Awareness Week 2015. Age related macular degeneration (AMD) is a progressive eye disease which is the leading cause of blindness in over 50s globally.

16 Sep 2015

Healthy diet and exercise can protect against AMD

People with a genetic predisposition for age-related macular degeneration (AMD) significantly increased their odds of developing the blinding eye disorder if they had a history of heavy smoking and consistently did not exercise or eat enough fruits and vegetables, according to an observational study of women funded by the National Eye Institute, part of the National Institutes of Health.

16 Sep 2015

New molecule shows efficacy in inhibiting inflammation, preventing premature delivery in murine models

Premature births are intimately linked with inflammation of the uterine tissue, a biological response which induces contractions and preterm labor. In their search for a mean to prevent this phenomenon and complications related to deliveries occurring before 37 weeks of gestation, researchers at CHU Sainte-Justine and University of Montreal discovered an agent that shows efficacy in inhibiting inflammation and preventing or delaying uterine contractions and premature delivery in murine models - without adversely affecting the fetus or the mother.

9 Sep 2015

Central visual field loss may delay driver's ability to detect pedestrians in timely manner

Vision researchers in Boston have published the second paper of a study designed to determine if a driver who suffers from loss of central vision is able to detect pedestrians in a timely manner when driving.

3 Sep 2015

Researchers discover that vitamin D may play significant role in preventing AMD among women

Vitamin D has been studied extensively in relation to bone health as well as cancer. Now, a team led by a researcher at the University at Buffalo has discovered that vitamin D may play a significant role in eye health, specifically in the possible prevention of age-related macular degeneration, or AMD, among women who are more genetically prone to developing the sight-damaging disease.

1 Sep 2015

Age Related Macular Degeneration News and Research

RXi Pharmaceuticals begins Phase 1/2 clinical trial in ophthalmology

Good news for patients suffering from dry age-related macular degeneration

Franziska Michor named recipient of NYSCF - Robertson Stem Cell Prize

NYSCF conference to focus on translational stem cell and neuroscience research

NAM announces election of three new members from UC San Diego School of Medicine

Allergan completes acquisition of AqueSys

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

Lonza, Benitec partner to develop scalable manufacturing process for AAV-based viral gene therapies

Envisia's ENV515 (travoprost XR) meets primary efficacy endpoint in phase 2a glaucoma trial

Oraya therapy is effective in maintaining vision with reduced injections for wet AMD patients

Adults with AMD are accurate, but slower in performing touch screen tasks

Matricellular proteins may be key therapeutic targets for common ocular disorders

Researchers receive NIH grants to find genomic regions containing variants that affect disease risk

UK’s GPs, optometrists confirm link between smoking and loss of vision

Benitec Biopharma initiates new site for ongoing Phase 1/2a TT-034 trial for hepatitis C

AMD Alliance hosts webinar to promote awareness and knowledge about macular disease

Healthy diet and exercise can protect against AMD

New molecule shows efficacy in inhibiting inflammation, preventing premature delivery in murine models

Central visual field loss may delay driver's ability to detect pedestrians in timely manner

Researchers discover that vitamin D may play significant role in preventing AMD among women

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