Angiotensin Converting Enzyme 2 News and Research

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Researchers identify a conserved site on SARS-CoV-2 spike that a broadly neutralizing macrocyclic peptide can target

Researchers explored the efficiency of a macrocyclic peptide in inhibiting the SARS-CoV-2 spike protein.

17 Nov 2022

SARS-CoV-2 ‘Deltacron’ variant exhibits immune-escape properties similar to Omicron BA.1

The SARS-CoV-2 Deltacron does not exhibit higher transmissibility or immune evasion than the Omicron BA.1 variant.

16 Nov 2022

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

In a recent study published in the journal npj Vaccines, researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer.

15 Nov 2022

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Researchers discuss the beneficial role of polyphenolic plant compounds in the Mediterranean diet in the prevention and treatment of COVID-19.

15 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

The viral fitness and antigenic relationship among Omicron sublineages

Researchers used mouse models and human airway cell cultures to investigate the relative viral replication rates and cross-neutralization against SARS-CoV-2 Omicron sublineages.

14 Nov 2022

Can monkeypox infection lead to myocarditis?

A recent study presents the first known case of myocarditis as a complication of monkeypox virus infection.

13 Nov 2022

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Millions have died due to COVID-19 infection, and millions more continue experiencing the chronic condition, Long COVID, which makes discovering practical, accessible, and powerful SARS-CoV-2 preventatives and COVID-19 treatments essential.

11 Nov 2022

Melatonin could be a potential therapy for long-COVID symptoms

A recent review published in the journal Biomolecules discussed the potential uses of melatonin in treating brain fog, and chronic fatigue syndrome or myalgic encephalomyelitis symptoms associated with long coronavirus disease (COVID)

9 Nov 2022

The direct and indirect effects of COVID-19 on people with type 1 and type 2 diabetes

A recent study published in The Lancet Diabetes & Endocrinology discussed the impact of COVID-19 on individuals with diabetes.

9 Nov 2022

Study indicates widespread SARS-CoV-2 exposure in wildlife

In a recent study posed to the bioRxiv* preprint server, researchers at Virginia Tech University investigated wildlife exposure to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).

8 Nov 2022

Does vitamin D reduce COVID-19 severity?

A new study examined published studies for a consistent association between vitamin D levels and coronavirus disease 2019 (COVID-19) severity.

8 Nov 2022

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

Researchers recently measured the neutralizing antibody titers against the wild-type strain of SARS-CoV-2 and the SARS-CoV-2 Omicron subvariants in healthcare workers fully vaccinated with three doses of the Comirnaty vaccine who experienced breakthrough Omicron infections.

8 Nov 2022

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

In a recent study published in the journal Annals of Diagnostic Pathology, researchers in the United States evaluated the impact of coronavirus disease 2019 (COVID-19) on central nervous system (CNS) damage in Alzheimer's disease (AD).

7 Nov 2022

SARS-CoV-2 activates NLRP3 inflammasome

Researchers assessed the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation.

7 Nov 2022

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Researchers generated and characterized two monoclonal antibodies (NA8 and NE12) that target the receptor binding domain of the SARS-CoV-2 spike protein, and exhibit neutralizing activity against major SARS-CoV-2 variants of concern.

3 Nov 2022

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

In a recent study posted to the medRxiv* preprint server, researchers in the United States investigated the source of an enigmatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)-like spike (S) protein strain detected in wastewater but not in clinical samples.

2 Nov 2022

Angiotensin Converting Enzyme 2 News and Research

Researchers identify a conserved site on SARS-CoV-2 spike that a broadly neutralizing macrocyclic peptide can target

SARS-CoV-2 ‘Deltacron’ variant exhibits immune-escape properties similar to Omicron BA.1

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

The viral fitness and antigenic relationship among Omicron sublineages

Can monkeypox infection lead to myocarditis?

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Melatonin could be a potential therapy for long-COVID symptoms

The direct and indirect effects of COVID-19 on people with type 1 and type 2 diabetes

Study indicates widespread SARS-CoV-2 exposure in wildlife

Does vitamin D reduce COVID-19 severity?

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

SARS-CoV-2 activates NLRP3 inflammasome

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

Vimentin is an important co-receptor for SARS-CoV-2 infection

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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