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Researchers explore how glial cells develop in the brain from neural precursor cells

Two types of cells are active in the brain: nerve cells and glial cells. The latter have long been regarded primarily as supportive cells, but it is increasingly recognized that they play an active role in the communication between neurons in the brain.

10 Dec 2018

New way of controlling HIV latency to completely eradicate the virus

A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent HIV are "invisible" to the natural defenses of the immune system.

7 Dec 2018

New therapeutic strategy is emerging for type 2 diabetes

Diabetes is a disease in which blood sugar levels are high over a prolonged period (hyperglycemia). In the case of type 2 diabetes, this phenomenon which is caused by a disruption of the glucose metabolism develops progressively and insidiously.

6 Dec 2018

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

In a piece of research conducted in collaboration, the NanoBioCel group of the UPV/EHU's Faculty of Pharmacy, and the University of Elche have designed some niosomes, which are lipid vesicles for use in gene therapies designed to treat diseases of the central nervous system.

4 Dec 2018

Researchers develop new technique to accurately isolate phloem cells across plants

Crops worldwide are increasingly vulnerable to pandemics, as diseases hitch rides on global flows of people and goods, hopping from continent to continent. Phloem diseases such as citrus greening are one particularly devastating group of plant diseases that have been wreaking economic havoc globally.

4 Dec 2018

Using nanocarrier-delivered microRNA to target sepsis

One in three patients who die in the U.S. dies of sepsis, according to the Centers for Disease Control and Prevention. It is one of the leading causes of death in intensive care units and, with an estimated price tag of $20 billion in 2011, the most expensive condition that hospitals treat.

3 Dec 2018

Scientists develop nanoscale tweezers that can move freely within cells

Researchers have developed nanoscale “tweezers” that can extract cellular components such as DNA, proteins, and organelles, without causing damage or bursting the cell.

3 Dec 2018

Study uncovers how HIV DNA is blocked from entering the cell nucleus

Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a study published November 29 in the open-access journal PLOS Pathogens by Michael Malim of King’s College London, and colleagues.

3 Dec 2018

Study shows for the first time how a specific cell gene affects transformation of others

An international team of seven institutions from Spain and the US including the University of Valencia has discovered for the first time that the biological activity of the c-MYC gene is necessary so that cell reprogramming occurs, that is, the process by which a specialised cell -for example, a neuron- is transformed into a different cell type.

30 Nov 2018

Researchers elucidate central mechanisms of salt-induced hypertension through sympathetic activation

Hypertension is a major risk factor for cardiovascular disease worldwide, and approximately 40% (1 billion) of adults aged 25 and above have been diagnosed with hypertension. A positive correlation between salt intake and blood pressure has long been postulated.

30 Nov 2018

Light-activated tools allow scientists to accurately probe intracellular phase separation

Creating new tools that harness light to probe the mysteries of cellular behavior, Princeton researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells.

30 Nov 2018

Scientists identify clues to brain changes in depression

In new pre-clinical research, scientists at the University of Maryland School of Medicine, led by Scott Thompson, PhD, Professor of Physiology, have identified changes in brain activity linked to the pleasure and reward system.

28 Nov 2018

Discovery could be used to prevent viral infection and autoimmunity

Researchers have discovered that chemical changes to mRNA regulate the production of interferon beta, and hope to exploit this in new treatments.

27 Nov 2018

Scientist uncovers hidden region of the human brain

A world-renowned expert has announced the discovery of a hidden brain region in humans that may be what differentiates humans from monkeys and other animals.

23 Nov 2018

Lower levels of protein make squamous carcinoma cells more invasive

Loss of a protein called TRIM29 promotes cancer cell invasion in a common type of skin cancer, suggesting a novel diagnostic marker and a possible therapeutic target.

21 Nov 2018

First probabilistic atlas of thalamus nuclei to better understand the brain

A multidisciplinary study led by BCBL, a Basque research center, opens the door to the investigation of the structure and functions of human thalamic nuclei and their involvement in Alzheimer's, dyslexia, epilepsy, Huntington's and schizophrenia.

20 Nov 2018

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Pushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular machines, as it locks onto DNA and loads the machinery for reading the genetic code.

20 Nov 2018

Researchers produce 3D chemical maps of small biological samples

Scientists at the National Synchrotron Light Source II --a U.S. Department of Energy (DOE) Office of Science User Facility at DOE's Brookhaven National Laboratory--have used ultrabright x-rays to image single bacteria with higher spatial resolution than ever before.

16 Nov 2018

Research team identifies Ashkenazi Jewish founder mutation for Leigh syndrome

Over 30 years ago, Marsha and Allen Barnett lost their sons to a puzzling childhood disease that relentlessly attacked their nervous systems and sapped their energy.

15 Nov 2018

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia

While it has long been recognized that mutated gene NPM1 plays an important role in acute myeloid leukemia, no one has determined how the normal and the mutated forms of the protein NPM1 function.

13 Nov 2018

Cell Nucleus News and Research

Researchers explore how glial cells develop in the brain from neural precursor cells

New way of controlling HIV latency to completely eradicate the virus

New therapeutic strategy is emerging for type 2 diabetes

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

Researchers develop new technique to accurately isolate phloem cells across plants

Using nanocarrier-delivered microRNA to target sepsis

Scientists develop nanoscale tweezers that can move freely within cells

Study uncovers how HIV DNA is blocked from entering the cell nucleus

Study shows for the first time how a specific cell gene affects transformation of others

Researchers elucidate central mechanisms of salt-induced hypertension through sympathetic activation

Light-activated tools allow scientists to accurately probe intracellular phase separation

Scientists identify clues to brain changes in depression

Discovery could be used to prevent viral infection and autoimmunity

Scientist uncovers hidden region of the human brain

Lower levels of protein make squamous carcinoma cells more invasive

First probabilistic atlas of thalamus nuclei to better understand the brain

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Researchers produce 3D chemical maps of small biological samples

Research team identifies Ashkenazi Jewish founder mutation for Leigh syndrome

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia

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From Discovery Biology to ELRIG Chair

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