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Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

About 40 % of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

Research could lead to new treatments for people with autoimmune disorders

The immune system is programmed to rid the body of biological bad guys--like viruses and dangerous bacteria--but its precision isn't guaranteed. In the tens of millions of Americans suffering from autoimmune diseases, the system mistakes normal cells for malicious invaders, prompting the body to engage in self-destructive behavior.

29 May 2019

New laboratory test has potential to accurately predict spread of breast cancer

Researchers at The Johns Hopkins University and other institutions report that a new laboratory test that induces cancer cells to squeeze through narrow spaces has the potential to accurately predict which breast cancers and other solid tumors are likely to spread, or metastasize, to other sites.

From Johns Hopkins Medicine 29 May 2019

Epigenetic research provides new approaches to cancer combination therapies

Epigenetic processes enable cells to respond to changes in their environment by regulating the activity of their genes.

28 May 2019

Provocation of obsessive thoughts induces physiological brain changes in 64-year-old man with OCD

Thoughts that lead to compulsive behavior in obsessive-compulsive disorder (OCD) correspond with physiological changes in the brain, according to a new case study. The article is published ahead of print in the Journal of Neurophysiology.

28 May 2019

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells.

28 May 2019

Study clarifies how 3D organization of genome is regulated at onset of skeletal muscle formation

A new study from the University of Minnesota Medical School clarifies how the three-dimensional organization of the genome is regulated at the onset of skeletal muscle formation.

25 May 2019

Spatial configuration of the genome is not inherited, but set up during embryogenesis

The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.

23 May 2019

GW researchers lay groundwork for improving diagnostic utility of neonatal EEGs

Neonatal brain injury is a leading cause of lifelong disability. Researchers at the George Washington University are laying the groundwork for a future where health care providers can more accurately diagnose brain injury and dysfunction in newborns with the use of an inexpensive and non-invasive diagnostic tool -- electroencephalography.

15 May 2019

Researchers elucidate the mechanism underlying dead-zone generation in circadian clocks

Most organisms on Earth have circadian clocks. In mammals, the circadian pacemaker is located in the suprachiasmatic nucleus of the brain.

14 May 2019

Researchers identify important signaling molecule in the biology of Hodgkin's lymphoma

Although classical Hodgkin's lymphoma is generally easily treatable today, many aspects of the disease still remain a mystery.

13 May 2019

Could deep brain stimulation help resolve the opioid epidemic?

Researchers have developed an implant that has shown promise for reducing addiction rates. However, there are major ethical and financial concerns, which we have tried to cover in this news story.

9 May 2019

Light therapy may dramatically reduce neurodegeneration in Alzheimer’s disease

Researchers at MIT have found that light therapy can enhance synaptic function and protect against cell death in Alzheimer’s disease.

9 May 2019

Promising radioisotope couple for cancer diagnosis and therapy

Researchers at Kanazawa University report in ACS Omega a promising combination of radioisotope-carrying molecules for use in radiotheranostics — a diagnosis-and-treatment approach based on the combination of medical imaging and internal radiation therapy with radioactive elements.

9 May 2019

Study finding promises new perspectives for treatment of Type 2 endometrial cancer

Brazilian scientists identify the predominant presence of a truncated variant of the p53 protein in amyloid aggregates in endometrial cancer cells. Such structures are related to the progression of this tumor.

3 May 2019

Scientists describe how cells 'decide' between pluripotency and differentiation

Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells “decide” which of these two directions to take.

3 May 2019

Scientists discover first gene involved in lower urinary tract obstruction

Even before birth, an obstructed urethra can cause a variety of issues in the unborn child, ranging from mild urinary problems to kidney failure.

2 May 2019

Researchers uncover new brain mechanisms regulating body weight

Researchers at University of Gothenburg, Sweden, clarify the link between the molecule interleukine-6 (IL-6) in the brain and obesity. In experiments on rats and mice they show that the molecule does affect the risk of obesity, and also where this effect occurs in the brain.

2 May 2019

Researchers gain new insight into Alzheimer's using organoids that resemble mini brains

In the majority of cases, dementia can be traced back to Alzheimer's disease. Its causes are not really understood yet. What is known is that plaques form from misfolded proteins and that there is an increase in neuronal cell death levels in the brain. However, the plaques don't necessarily go hand in hand with any symptoms.

30 Apr 2019

Obesity linked to a reduction in gray matter

A new study suggests that obesity may be associated with changes in brain structure, including reduced brain volumes in certain areas.

24 Apr 2019

Cell Nucleus News and Research

Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

Research could lead to new treatments for people with autoimmune disorders

New laboratory test has potential to accurately predict spread of breast cancer

Epigenetic research provides new approaches to cancer combination therapies

Provocation of obsessive thoughts induces physiological brain changes in 64-year-old man with OCD

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Study clarifies how 3D organization of genome is regulated at onset of skeletal muscle formation

Spatial configuration of the genome is not inherited, but set up during embryogenesis

GW researchers lay groundwork for improving diagnostic utility of neonatal EEGs

Researchers elucidate the mechanism underlying dead-zone generation in circadian clocks

Researchers identify important signaling molecule in the biology of Hodgkin's lymphoma

Could deep brain stimulation help resolve the opioid epidemic?

Light therapy may dramatically reduce neurodegeneration in Alzheimer’s disease

Promising radioisotope couple for cancer diagnosis and therapy

Study finding promises new perspectives for treatment of Type 2 endometrial cancer

Scientists describe how cells 'decide' between pluripotency and differentiation

Scientists discover first gene involved in lower urinary tract obstruction

Researchers uncover new brain mechanisms regulating body weight

Researchers gain new insight into Alzheimer's using organoids that resemble mini brains

Obesity linked to a reduction in gray matter

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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