DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Study finds way to reverse gene silencing in inner ear cells

A deafened adult cannot recover the ability to hear, because the sensory hearing cells of the inner ear don't regenerate after damage.

14 Aug 2023

Scientists identify key proteins driving cancer across multiple tumor types

Scientists have completed a deep analysis of the proteins driving cancer across multiple tumor types, information that can't be assessed by genome sequencing alone.

14 Aug 2023

Exploring DNA methylation biomarkers of multiple sclerosis

Researchers identify cell-specific DNA methylation signatures associated with MS.

14 Aug 2023

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

10 Aug 2023

High-level BPA exposure may affect male fertility

Scientists discuss the effect of bisphenol A on human male fertility.

9 Aug 2023

Exploring human aging via elephant research

Indiana University researcher Daniella Chusyd is studying human aging in an unlikely way: through elephants.

4 Aug 2023

Transcription factors may drive development of different colorectal cancer subtypes

New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors — proteins that help turn specific genes on or off by binding to nearby DNA — may play a central role in the degree of DNA methylation across the genome, contributing to the development of different subtypes of these cancers.

27 Jul 2023

Henry Ford Health researcher wins grant to study circulating cell-free DNA methylation as a tool for glioma detection

Houtan Noushmehr, Ph.D., a researcher at Henry Ford Health, has been awarded a prestigious R01 grant of nearly $2.9M from the National Institutes of Health (NIH) to support a research project titled, "Circulating cell-free DNA methylation as an accurate tool for detection and clinical follow-up of glioma."

27 Jul 2023

Can epigenetic changes explain the strong link between age and cancer?

Researchers reported the link between aging, cancer, and epigenomic changes.

26 Jul 2023

Eternal youth? Chemical cocktails prove effective in cell age reversal

Researchers identified chemical drug combinations that could reverse cellular aging.

19 Jul 2023

The role of airway epithelium: insights into asthma and COPD pathogenesis

Study discussed how injury and abnormal repair of the airway epithelium drive chronic obstructive pulmonary disease (COPD) and asthma.

17 Jul 2023

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Researchers develop and characterize a highly specific EpiEditing system using catalytically inactivated catalytically inactivated Cas9.

17 Jul 2023

Exploring the relationship between epigenetic aging and gut microbiome composition in physically fit men and women

Researchers investigate the relationship between the gut microbiome, physical fitness, and epigenetic aging in physically fit individuals.

14 Jul 2023

New study links perfluoroalkyl substance exposure to childhood asthma phenotypes

Study evaluated the effects of exposure to perfluoroalkyl substances on asthma phenotypes.

13 Jul 2023

THC use during pregnancy could lead to life-long health impacts for offspring

Oregon Health & Science University researchers showed that consuming THC while pregnant could potentially affect development of the fetus and lead to life-long health impacts for offspring.

6 Jul 2023

Does a healthy diet protect against dementia and slow the pace of biological aging?

Study tested whether healthy diets slowed biological aging and, thus, dementia.

6 Jul 2023

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Study identified a genome-wide significant association (GWAS) for long coronavirus disease.

6 Jul 2023

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

In a significant development in the fight against fatal cancers, University of Otago researchers have pinpointed a key feature that leads to the aggressive spread of colon cancer.

26 Jun 2023

Research reveals devastating impact of Western diet on human health

Research examines the impact of the Western diet on various aspects of health, including metabolism, inflammation, gut microbiota, cardiovascular health, mental health, and cancer. It provides insights into the effects of this dietary pattern on individuals and healthcare systems.

18 Jun 2023

Study reveals surprising link between biological age and child development

Study explores the relationship between accelerated biological age in children, as indicated by telomere length and DNA methylation age, and various developmental outcomes. It aims to clarify the impact of accelerated biological age on growth, cognition, behavior, lung function, and puberty onset in European school-age children.

7 Jun 2023

DNA Methylation News and Research

Further Reading

Study finds way to reverse gene silencing in inner ear cells

Scientists identify key proteins driving cancer across multiple tumor types

Exploring DNA methylation biomarkers of multiple sclerosis

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

High-level BPA exposure may affect male fertility

Exploring human aging via elephant research

Transcription factors may drive development of different colorectal cancer subtypes

Henry Ford Health researcher wins grant to study circulating cell-free DNA methylation as a tool for glioma detection

Can epigenetic changes explain the strong link between age and cancer?

Eternal youth? Chemical cocktails prove effective in cell age reversal

The role of airway epithelium: insights into asthma and COPD pathogenesis

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Exploring the relationship between epigenetic aging and gut microbiome composition in physically fit men and women

New study links perfluoroalkyl substance exposure to childhood asthma phenotypes

THC use during pregnancy could lead to life-long health impacts for offspring

Does a healthy diet protect against dementia and slow the pace of biological aging?

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Researchers pinpoint a key feature that leads to aggressive spread of colon cancer

Research reveals devastating impact of Western diet on human health

Study reveals surprising link between biological age and child development

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