Viral hemorrhagic fevers (VHFs) refer to a group of illnesses that are caused by several distinct families of viruses. In general, the term "viral hemorrhagic fever" is used to describe a severe multisystem syndrome (multisystem in that multiple organ systems in the body are affected). Characteristically, the overall vascular system is damaged, and the body's ability to regulate itself is impaired. These symptoms are often accompanied by hemorrhage (bleeding); however, the bleeding is itself rarely life-threatening. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause severe, life-threatening disease.
Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) are the most important vector-borne viral diseases in the World. Around 50-100 million cases appear each year putting 2.5 billion people at risk of suffering this debilitating and sometimes fatal disease.
Scientists at Columbia University's Mailman School of Public Health, the South African National Institute for Communicable Diseases of National Health Laboratory Service (NICD-NHLS), the U.S. Centers for Disease Control and Prevention, and Roche's 454 Life Sciences Corporation have discovered the new virus responsible for a highly fatal hemorrhagic fever outbreak in Zambia and South Africa in late 2008.
Researchers at Brandeis, in collaboration with several other institutions worldwide, have pinpointed for the first time the multi-country economic costs of dengue fever, the endemic and epidemic mosquito-borne illness that is a rapidly growing public health problem in tropical and sub-tropical countries.
An epidemic of the viral disease nephropathia epidemica (NE) has been linked to increases in the vole population caused by hotter summers, milder winters and increased seedcrop production by broadleaf trees.
Research led by Iowa State University scientists has them a step closer to finding a way to counter the Ebola virus.
Peregrine Pharmaceuticals, Inc. has announced that the U.S. Patent and Trademark Office has issued U.S. Patent Number No. 7,455,833, which includes broad claims covering anti-viral applications of antibodies that directly bind to aminophospholipids.
Bavituximab, an anti-viral drug developed by UT Southwestern Medical Center researchers, shows promise as a new strategy to fight viral diseases, including potential bioterrorism agents.
Scientists report the discovery of a new species of Ebola virus, provisionally named Bundibugyo ebolavirus, November 21 in the open-access journal PLoS Pathogens.
In a new study reported in PLoS Medicine, Mammen P. Mammen Jr. of the Armed Forces Research Institute of Medical Sciences (AFRIMS) in Bangkok and colleagues investigated the spread of dengue virus infection in rural Thai villages.
Scientists at the Scripps Research Institute have uncovered the structure of a critical protein from the Ebola Virus that allows viral entry in human cells.
Described in the July 10, 2008 issue of the journal Nature, the research reveals the shape of the Ebola virus spike protein, which is necessary for viral entry into human cells, bound to an immune system antibody acting to neutralize the virus. The structure provides a major step forward in understanding how the deadly virus works, and may be useful in the development of potential Ebola virus vaccines, or treatments for those infected.
A team of Bolivian health authorities, U.S. Navy health experts based in Lima, Peru, and the U.S. Centers for Disease Control and Prevention has characterized "Chapare arenavirus," a previously unrecognized arenavirus, discovered in serum samples from a patient in rural Bolivia who eventually died of the infection.
Mosquitoes responsible for spreading disease are increasingly becoming resistant to synthetic insecticides.
Australian Health officials have issued public health warnings about mosquito bourne diseases in three areas.
Yellow fever is a zoonosis of the tropical regions of South America and Africa, which occurs in two distinct epidemiologic cycles: jungle and urban.
Scientists in the United States say that they have found a way to make the lethal Ebola virus harmless in the laboratory.
The deadly Ebola virus, an emerging public health concern in Africa and a potential biological weapon, ranks among the most feared of exotic pathogens.
In connection with last year's epidemic, a research team at Umea University in Sweden has managed for the first time to show that hantavirus exists in human saliva; this raises the question of whether this contagion can spread among humans
Health officials in the U.S. say the tropical infection Dengue fever is in danger of spreading across the country.
A disease most Americans have never heard of could soon become more prevalent if dengue, a flu-like illness that can turn deadly, continues to expand into temperate climates and increase in severity, according to a new commentary by Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and David M. Morens, M.D., Fauci's senior scientific advisor.
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