Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

What are the characteristics of misdiagnosed human mpox cases?

In a recent study, researchers characterized overlooked cases of monkeypox (MPX).

21 Dec 2022

First cell-type specific multiomic study of the HIV brain

Researchers identify cell-type-specific differences in HIV integration sites in the brain.

19 Dec 2022

Immune-evading Mycobacterium tuberculosis prevents inflammatory responses by hijacking the host’s ubiquitin

A new study discussed the findings of Chai et al., which revealed that triple specificity protein phosphatase (ptpB) secreted by Mycobacterium tuberculosis inhibits pyroptosis and the release of cytokines by macrophages, allowing M. tuberculosis to invade the immune system.

19 Dec 2022

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Researchers investigated whether coronavirus disease 2019 (COVID-19)-associated chemosensory alterations were predictive of serological responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among United States (US) residents.

16 Dec 2022

The mpox viral load kinetics over time in various parts of the body

Researchers characterized the time to mpox virus clearance of immunocompetent individuals with mild MPX in a real-world community-based setting utilizing longitudinal information.

16 Dec 2022

Medicaid expansion and increase in PrEP, antiretroviral treatment could result in decline of new HIV infections

Enacting Medicaid expansion in Texas and increasing the use of preventive and antiviral medications could result in a decline of new HIV infections among young Black gay, bisexual, and other men who have sex with men (MSM) in Houston, reports a study in the January issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.

13 Dec 2022

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Researchers assessed the impact of bebtelovimab (BEB) monoclonal antibody in the treatment of high-risk SARS-CoV-2 Omicron variant-infected patients.

13 Dec 2022

Knowledge and attitudes to mpox among GBMSM in Australia

Researchers presented the results of a cross-sectional survey done in Australia between August and September 2022.

12 Dec 2022

HIV-positive people are protected by Covid vaccines

People infected with HIV who receive antiretroviral therapy form antibodies against Sars-Cov-2 after being vaccinated against Covid with mRNA vaccines.

9 Dec 2022

Enveloped viruses show greater cross-species transmission, according to new research

New research found that enveloped viruses harbor greater cross-species transmissibility and are more likely to cause zoonotic infections than nonenveloped viruses.

9 Dec 2022

Exploring immunogenicity, boosting efficacy and safety of modified vaccinia Ankara-Bavarian Nordic vaccine

Researchers evaluated the immunogenicity, boosting efficacy, and safety of single-dose and two-dose MVA-BN (modified vaccinia Ankara-Bavarian Nordic) vaccinations in comparison to replicating smallpox vaccines.

7 Dec 2022

The effect of evolutionary changes in prolonged SARS-CoV-2 infection in an immunosuppressed individual due to advanced HIV

Researchers assessed the impact of SARS-CoV-2 infection on cell death and fusion in an immunocompromised host.

30 Nov 2022

Study on mpox epidemiology in New York during summer 2022

Researchers presented a summary of their experience of identifying, managing, and vaccinating monkeypox (MPX) virus (MPXV)-infected individuals in New York during the summer season of 2022.

30 Nov 2022

Monkeypox renamed "mpox" in an effort to combat stigma

WHO announces that the monkeypox virus will now be referred to as “mpox” in an effort to reduce the stigmatization of this condition.

29 Nov 2022

How do COVID-19 outcomes vary by race and gender?

Researchers investigated the variations in coronavirus disease 2019 (COVID-19) testing and severe outcomes according to race, ethnicity, and gender.

29 Nov 2022

Establishment of quantitative scale for long COVID stigma estimation among UK residents

Researchers developed and validated the long coronavirus disease (COVID) stigma scale (LCSS) to quantify the burden of long COVID stigma in the United Kingdom (UK).

28 Nov 2022

How national programs leveraged PEPFAR-supported laboratory resources for SARS-CoV-2 testing during the COVID-19 pandemic

Researchers described ways in which national-level programs leveraged PEPFAR [president’s emergency plan for acquired immunodeficiency syndrome (AIDS) relief]-aided laboratory-based resources for SARS-CoV-2 testing during COVID-19.

24 Nov 2022

Study shows no undetected monkeypox virus transmission before May 2022 in Rotterdam and Amsterdam

Researchers investigated whether undetected human monkeypox virus transmission occurred before Rotterdam and Amsterdam's first documented monkeypox cases.

23 Nov 2022

SARS-CoV-2 seroprevalence in domestic cats has increased over time

Researchers evaluated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission among domestic cats in the United Kingdom (UK).

22 Nov 2022

Epidemiological and clinical characteristics of monkeypox virus infection in cis and trans women and non-binary individuals

A recent study described the clinical and epidemiologic features of infection with monkeypox virus (MPXV) in cisgender (cis) and transgender (trans) females and non-binary individuals.