Rheumatism News and Research

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Rheumatism is a group of disorders marked by inflammation or pain in the connective tissue structures of the body. These structures include bone, cartilage, and fat.

BioCryst second quarter total revenues decrease to $3.7 million

BioCryst Pharmaceuticals, Inc. announced financial results for the second quarter and six months ended June 30, 2011.

4 Aug 2011

New study shows high prevalence of gout in the U.S.

A new study shows the prevalence of gout in the U.S. has risen over the last twenty years and now affects 8.3 million (4%) Americans.

28 Jul 2011

Three factors contribute to systemic scleroderma-related work disability

Systemic scleroderma has slowed Tracy Zinn but it has not stopped her from working. Thanks in part to determination and an accommodating employer, Zinn is now in her 13th year as an account executive for a firm that produces educational software. But, many with the incapacitating disease are not as fortunate.

13 Jul 2011

High BMI and vigorous physical activity increase risk of arthroplasty in men

Surprising results from a new study revealed that men who smoke had less risk of undergoing total joint replacement surgery than those who never smoked.

8 Jul 2011

Incidence of osteoarthritis more prevalent among military populations

New research shows significantly higher osteoarthritis (OA) incidence rates in military populations than among comparable age groups in the general population.

30 Jun 2011

Study explores link between hospital procedure volume, surgical outcomes after joint replacements

Patients who undergo elective total hip or total knee arthroplasty at hospitals with lower surgical volume had a higher risk of venous thromboembolism and mortality following the procedure.

7 Jun 2011

Positive data from Augurex's RA biomarker blood test, novel drug target presented at EULAR conference

Augurex Life Sciences Corp. today reported that in London at the European League Against Rheumatism Conference, leading arthritis researchers presented important data on Augurex's rheumatoid arthritis biomarker blood test and novel drug target.

30 May 2011

New positive Cimzia phase IIIb study data on rheumatoid arthritis presented at EULAR meeting

UCB today announced data which showed that the addition of Cimzia to current therapy was associated with a rapid and consistent clinical response in a diverse group of rheumatoid arthritis (RA) patients.

30 May 2011

Study: Cardiovascular disease may be under treated in rheumatoid arthritis patients

Results of a study, involving 98,454 patients demonstrated that at 30 days following their first heart attack, RA patients were approximately 20% less likely to be prescribed standard MI treatments, such as statins and betablockers, compared to healthy patients.

27 May 2011

Adalimumab plus methotrexate helps achieve higher levels of disease control in early RA

Data presented today at the EULAR 2011 Annual Congress demonstrated that initial treatment with adalimumab (Humira, ADA) plus methotrexate in early RA patients can provide high levels of disease control in many patients, and may also offer the opportunity to change future treatment options for some.

27 May 2011

Gout drug success for Novartis

Novartis AG's new gout therapy drug gives patients better pain relief and significantly cuts the risk of new attacks say two late stage studies. The studies show that more than 450 patients taking Ilaris, or ACZ885, had less pain and the risk of new attacks were reduced by up to 68 percent compared to those taking an injectable steroid to treat gouty arthritis attacks, which can last for a week or more.

26 May 2011

Specific influenza immunization strategies for RA patients may be required for future flu pandemics

A Brazilian hospital-based study assessed responses to flu vaccines in 340 RA patients in regular follow-up compared to 234 healthy patients.

26 May 2011

HPV vaccination does not affect rate of disease flares in patients with SLE, study finds

Results of a Chinese study showed that the HPV vaccine did not have significant effects on the number of disease flares or antibody measures in patients with inactive SLE receiving stable doses of medications after administration, and therefore was determined safe to use to prevent HPV in this group of patients.

26 May 2011

Patients with Sj-gren's syndrome have emotional problems, worse mental wellbeing

The results of a Dutch study of 300 patients demonstrated that 22% of patients with Sj-gren's syndrome were classified as clinically 'alexithymic' compared to 12% of healthy controls. Subsequent results of the study showed that higher levels of alexithymia were moderately correlated with worse mental wellbeing in both groups (Pearson's correlation (r) ≥ 0.32, p< 0.001), showing that there is a proven link between the two.

26 May 2011

BioCryst presents positive data from two BCX4208 Phase 2 studies in gout at EULAR 2011

BioCryst Pharmaceuticals, Inc. presented positive data from its two completed, randomized, double-blind, placebo-controlled Phase 2 studies of BCX4208 in patients with gout at the Annual European Congress of Rheumatology hosted by the European League Against Rheumatism in London, U.K.

26 May 2011

Yoga improves quality of life in patients with fibromyalgia, rheumatoid arthritis

Individuals with rheumatoid arthritis who practice yoga showed statistically significant improvements in disease activity, according to a small study presented at the EULAR 2011 Annual Congress.

26 May 2011

Patients with celiac disease 4.5 times more likely to develop osteoporosis

Patients with celiac disease are more than 4.5 times more likely to develop osteoporosis compared to healthy people in an age and gender matched cohort with no identifiable risk factors for osteoporosis, according to a study presented today at the EULAR 2011 Annual Congress.

26 May 2011

Patients with rheumatoid arthritis two times more likely to have concurrent COPD

Patients with rheumatoid arthritis are two times more likely to have concurrent chronic obstructive pulmonary disease than healthy controls -- an association which was sustained even when variables such as age, gender, smoking and obesity were controlled for, according to a study presented today at the EULAR 2011 Annual Congress.

26 May 2011

Tofacitinib safe and effective for patients with rheumatoid arthritis

Results of a Phase III study presented today at the EULAR 2011 Annual Congress show that at 6 months, 58.3 percent of patients who had previously not responded to treatment with DMARDs, achieved ACR20 response when treated with the novel oral Janus kinase inhibitor tofacitinib at 10mg BID compared to 31.2 percent in the placebo group. Significant improvements were also observed in the 5 mg BID dose.

26 May 2011

Impact of gaming devices on finger and wrist pain in children presented at EULAR 2011

For the first time, results on the impact of gaming devices on finger and wrist pain in children were presented today at the EULAR 2011 Annual Congress. Data comparing two schools in the USA demonstrate that young children experience high levels of pain following long term use of gaming devices and mobile phones indicating that excessive gaming may negatively impact on joint health.

26 May 2011

Rheumatism News and Research

Further Reading

BioCryst second quarter total revenues decrease to $3.7 million

New study shows high prevalence of gout in the U.S.

Three factors contribute to systemic scleroderma-related work disability

High BMI and vigorous physical activity increase risk of arthroplasty in men

Incidence of osteoarthritis more prevalent among military populations

Study explores link between hospital procedure volume, surgical outcomes after joint replacements

Positive data from Augurex's RA biomarker blood test, novel drug target presented at EULAR conference

New positive Cimzia phase IIIb study data on rheumatoid arthritis presented at EULAR meeting

Study: Cardiovascular disease may be under treated in rheumatoid arthritis patients

Adalimumab plus methotrexate helps achieve higher levels of disease control in early RA

Gout drug success for Novartis

Specific influenza immunization strategies for RA patients may be required for future flu pandemics

HPV vaccination does not affect rate of disease flares in patients with SLE, study finds

Patients with Sj-gren's syndrome have emotional problems, worse mental wellbeing

BioCryst presents positive data from two BCX4208 Phase 2 studies in gout at EULAR 2011

Yoga improves quality of life in patients with fibromyalgia, rheumatoid arthritis

Patients with celiac disease 4.5 times more likely to develop osteoporosis

Patients with rheumatoid arthritis two times more likely to have concurrent COPD

Tofacitinib safe and effective for patients with rheumatoid arthritis

Impact of gaming devices on finger and wrist pain in children presented at EULAR 2011

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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