Study explores link between hospital procedure volume, surgical outcomes after joint replacements

Greater risk of blood clots and mortality following hip or knee arthroplasty

Patients who undergo elective total hip or total knee arthroplasty at hospitals with lower surgical volume had a higher risk of venous thromboembolism and mortality following the procedure. The complications following joint replacement surgery at low-volume sites may be reduced by modifying systems and procedures used before and after surgery according to the findings published today in Arthritis & Rheumatism, a peer-reviewed journal of the American College of Rheumatology (ACR).

The ACR estimates that 27 million Americans over the age of 25 have doctor-diagnosed osteoarthritis and another 1.3 million US adults suffer with rheumatoid arthritis. For patients with end-stage hip and knee arthritis, total hip and knee arthroplasty are highly successful surgical interventions that offer patients significant improvement in pain, function and health-related quality of life. According to the Centers for Disease Control and Prevention (CDC) National Hospital Discharge Survey, roughly 230,000 total hip replacements and 543,000 total knee replacements were performed in the U.S. in 2007.

The current study explored the relationship between hospital procedure volume and surgical outcomes following primary total hip or total knee replacements. "With the large number of elective arthroplasty in the U.S, it is important to understand the impact of peri- and post-operative medical complications on the success of joint replacement surgery," said lead author Jasvinder Singh, MD, MPH of the University of Alabama. "Possible cardiac complications, blood clots, or infections increase patient morbidity and mortality risk, which can lead to higher health care utilization and costs."

Researchers used the Pennsylvania Health Care Cost Containment Council database to identify the number of patients who underwent total hip replacement.

The findings show that patients who had primary total hip arthroplasty at low-volume hospitals were more likely to develop a pulmonary embolism (within 30 days of surgery) than those who had surgery at a high-volume hospital. One-year mortality was also higher for patients having total hip replacements at low-volume hospitals.

Researchers found that for total knee arthroplasty, patients age 65 and older had significantly higher odds for one-year mortality when surgeries were performed at low-volume hospitals compared to higher volume hospitals.

The authors theorize that the causes of complications at low-volume hospitals could be connected to hospital procedures and peri- and post-operative care processes. One example cited is differences in the selection of the best medication and device used to prevent blood clots following elective joint replacement surgery. The authors also suggest that the outcome of surgery is impacted by time of initiation and cessation of the clot prevention therapy. Dr. Singh concluded, "Further studies are needed to investigate whether the underlying reasons for poor surgical outcomes at low-volume hospitals are modifiable and which interventions may reduce complications for patients at these facilities."