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BMI's influence on disease pathogenesis uncovered in new research

The study highlights BMI's role in mediating genetic risk for diseases, suggesting a complex relationship with conditions like heart failure and osteoarthritis.

14 Nov 2024

New study highlights the importance of BMI in disease pathogenesis

New study from deCODE genetics/Amgen highlights the importance of BMI in pathogenesis of disease, suggesting that reducing BMI alone could lower the risk of several diseases.

12 Nov 2024

Does more education reshape your brain?

Researchers found no long-term brain structure changes from an extra year of compulsory education, challenging theories about education's impact on neural development.

10 Nov 2024

Researchers find 41 new genetic regions linked to disc herniations

Lumbar disc herniation is one of the most common structural changes in the lower back and the most common cause of radiating pain, or sciatica, in the leg.

7 Nov 2024

Healthy lifestyle choices can offset genetic risk for brain diseases

Christopher D. Anderson, MD, MSc, chief of the Division of Stroke and Cerebrovascular Diseases at Brigham and Women's Hospital and associate neurologist in the Department of Neurology and Center for Genomic Medicine at Massachusetts General Hospital, is the corresponding author and Jonathan Rosand, MD, MSc, co-founder of the McCance Center for Brain Health and neurologist in the Department of Neurology and Center for Genomic Medicine at Massachusetts General Hospital, is an author of a paper published on November 6, 2024, in Neurology, the medical journal of the American Academy of Neurology, "Health-related behaviors and risk of common age-related brain diseases across severities of genetic risk."

6 Nov 2024

New research explores how omega-3 and omega-6 fatty acids may impact cancer rates

This study highlights the relationship between polyunsaturated fatty acids and cancer risk, suggesting blood biomarkers may be key for accurate assessment.

6 Nov 2024

AI-powered ECG model predicts heart disease risk with precision

A new AI-enhanced ECG model, AIRE, accurately predicts mortality and heart disease risk, providing clinicians with actionable, patient-specific insights.

5 Nov 2024

Low-sugar diet in early life reduces risk of chronic diseases in adulthood

A low-sugar diet in utero and in the first two years of life can meaningfully reduce the risk of chronic diseases in adulthood, a new study has found, providing compelling new evidence of the lifelong health effects of early-life sugar consumption.

1 Nov 2024

1950’s sugar rationing policies reduced risks of hypertension and diabetes

The study links early-life sugar exposure to chronic disease risk, suggesting that sugar restriction could enhance health and reduce diabetes and hypertension.

31 Oct 2024

Study questions causal link between cannabis and brain changes

Lifetime cannabis use is associated with several changes in brain structure and function in later life, suggests an observational study, but these associations may not be causal, finds a genetic analysis of the same data, published in the open access journal BMJ Mental Health.

30 Oct 2024

Machine learning reveals secrets of aging in flies and humans

Discoveries that impact lifespan and healthspan in fruit flies are usually tested in mice before being considered potentially relevant in humans, a process that is expensive and time intensive. A pioneering approach taken at the Buck Institute leapfrogs over that standard methodology.

30 Oct 2024

Study reveals impact of daylight saving time on sleep patterns

With the clocks going back this weekend, a new study has found that moving the clocks one hour forward in Spring and one hour back in Autumn has a substantial, but short-lived effect on sleep duration.

25 Oct 2024

FUSE: Revolutionizing the analysis of gene mutations

Our study introduces a new tool called FUSE (Functional Substitution Estimation) that helps scientists better understand how changes in genes affect proteins.

25 Oct 2024

Long-term air pollution exposure linked to increased risk of acute kidney injury and mortality

Prolonged exposure to air pollutants like PM2.5 and nitrogen oxides significantly raises acute kidney injury risk and related mortality, urging policy action.

24 Oct 2024

Study connects brain volume variations with genetic risk factors for Parkinson’s disease and ADHD

Unprecedented genome analysis reveals genetic links between brain structure and disorders like Parkinson's and ADHD, paving the way for innovative treatments.

23 Oct 2024

Researchers identify genetic links to brain volume and disorders

In one of the largest-ever studies of DNA and brain volume, researchers have identified 254 genetic variants that shape key structures in the "deep brain," including those that control memory, motor skills, addictive behaviors and more.

21 Oct 2024

Genetic analysis shows smoking and high BMI increase dementia risk, but education and exercise protect

Mendelian randomization of 400,000 participants reveals smoking, high BMI, and high cholesterol as major genetic risk factors for dementia, while longer education and physical activity reduce risks.

17 Oct 2024

Bright night light exposure increases mortality risk, while daylight reduces it

Study reveals that brighter night light exposure and circadian rhythm disruption significantly increase the risk of mortality, particularly from cardiometabolic diseases, while brighter daytime light lowers these risks.

16 Oct 2024

Study reveals genetic factors affecting birth sex ratios

Each year, roughly the same numbers of boys and girls are born.

16 Oct 2024

Standing more may not improve cardiovascular health

Standing has gained popularity among people looking to offset the harms of a sedentary lifestyle often caused by spending long days sitting in front of the computer, television or driving wheel.

16 Oct 2024